Experiment: Rifampicin 0.004 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_2205 and Pf1N1B4_2206 overlap by 20 nucleotides Pf1N1B4_2206 and Pf1N1B4_2207 are separated by 198 nucleotides Pf1N1B4_2207 and Pf1N1B4_2208 are separated by 18 nucleotides
Pf1N1B4_2205 - Sterol desaturase, at 2,517,391 to 2,518,638
_2205
Pf1N1B4_2206 - FIG139438: lipoprotein B, at 2,518,619 to 2,519,251
_2206
Pf1N1B4_2207 - Porphobilinogen synthase (EC 4.2.1.24), at 2,519,450 to 2,520,463
_2207
Pf1N1B4_2208 - Polyphosphate kinase (EC 2.7.4.1), at 2,520,482 to 2,522,704
_2208
Position (kb)
2519
2520
2521 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 2518.466 kb on + strand, within Pf1N1B4_2205 at 2518.466 kb on + strand, within Pf1N1B4_2205 at 2518.466 kb on + strand, within Pf1N1B4_2205 at 2518.467 kb on - strand, within Pf1N1B4_2205 at 2518.535 kb on + strand at 2518.535 kb on + strand at 2518.535 kb on + strand at 2518.535 kb on + strand at 2518.535 kb on + strand at 2518.535 kb on + strand at 2518.535 kb on + strand at 2518.536 kb on - strand at 2518.536 kb on - strand at 2518.536 kb on - strand at 2518.536 kb on - strand at 2518.573 kb on + strand at 2518.574 kb on - strand at 2518.600 kb on + strand at 2518.600 kb on + strand at 2518.601 kb on - strand at 2518.608 kb on + strand at 2518.609 kb on - strand at 2518.636 kb on + strand at 2518.636 kb on + strand at 2518.637 kb on - strand at 2518.637 kb on - strand at 2518.637 kb on - strand at 2518.686 kb on + strand, within Pf1N1B4_2206 at 2518.686 kb on + strand, within Pf1N1B4_2206 at 2518.686 kb on + strand, within Pf1N1B4_2206 at 2518.686 kb on + strand, within Pf1N1B4_2206 at 2518.687 kb on - strand, within Pf1N1B4_2206 at 2518.687 kb on - strand, within Pf1N1B4_2206 at 2518.687 kb on - strand, within Pf1N1B4_2206 at 2518.749 kb on - strand, within Pf1N1B4_2206 at 2518.779 kb on + strand, within Pf1N1B4_2206 at 2518.779 kb on + strand, within Pf1N1B4_2206 at 2518.779 kb on + strand, within Pf1N1B4_2206 at 2518.779 kb on + strand, within Pf1N1B4_2206 at 2518.780 kb on - strand, within Pf1N1B4_2206 at 2518.780 kb on - strand, within Pf1N1B4_2206 at 2518.780 kb on - strand, within Pf1N1B4_2206 at 2518.828 kb on - strand, within Pf1N1B4_2206 at 2518.888 kb on - strand, within Pf1N1B4_2206 at 2518.888 kb on - strand, within Pf1N1B4_2206 at 2518.993 kb on + strand, within Pf1N1B4_2206 at 2518.994 kb on - strand at 2518.994 kb on - strand, within Pf1N1B4_2206 at 2519.076 kb on + strand, within Pf1N1B4_2206 at 2519.076 kb on + strand, within Pf1N1B4_2206 at 2519.077 kb on - strand, within Pf1N1B4_2206 at 2519.097 kb on + strand, within Pf1N1B4_2206 at 2519.097 kb on + strand at 2519.097 kb on + strand, within Pf1N1B4_2206 at 2519.097 kb on + strand, within Pf1N1B4_2206 at 2519.097 kb on + strand at 2519.098 kb on - strand, within Pf1N1B4_2206 at 2519.098 kb on - strand, within Pf1N1B4_2206 at 2519.098 kb on - strand, within Pf1N1B4_2206 at 2519.098 kb on - strand at 2519.126 kb on + strand, within Pf1N1B4_2206 at 2519.126 kb on + strand, within Pf1N1B4_2206 at 2519.127 kb on - strand at 2519.127 kb on - strand, within Pf1N1B4_2206 at 2519.142 kb on + strand, within Pf1N1B4_2206 at 2519.142 kb on + strand, within Pf1N1B4_2206 at 2519.142 kb on + strand, within Pf1N1B4_2206 at 2519.143 kb on - strand, within Pf1N1B4_2206 at 2519.143 kb on - strand, within Pf1N1B4_2206 at 2519.143 kb on - strand, within Pf1N1B4_2206 at 2519.285 kb on - strand at 2519.341 kb on + strand at 2519.342 kb on - strand at 2519.342 kb on - strand at 2519.394 kb on + strand at 2519.395 kb on - strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.405 kb on + strand at 2519.406 kb on - strand at 2519.406 kb on - strand at 2519.406 kb on - strand at 2519.406 kb on - strand at 2519.406 kb on - strand at 2519.406 kb on - strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.407 kb on + strand at 2519.408 kb on - strand at 2519.408 kb on - strand at 2519.408 kb on - strand at 2519.408 kb on - strand at 2519.544 kb on + strand at 2519.544 kb on + strand at 2519.544 kb on + strand at 2519.544 kb on + strand at 2519.545 kb on - strand at 2519.822 kb on - strand, within Pf1N1B4_2207 at 2519.848 kb on + strand, within Pf1N1B4_2207 at 2519.888 kb on + strand, within Pf1N1B4_2207 at 2519.888 kb on + strand, within Pf1N1B4_2207 at 2519.888 kb on + strand, within Pf1N1B4_2207 at 2519.888 kb on + strand, within Pf1N1B4_2207 at 2519.906 kb on - strand, within Pf1N1B4_2207 at 2519.924 kb on - strand, within Pf1N1B4_2207 at 2520.053 kb on + strand, within Pf1N1B4_2207 at 2520.054 kb on - strand, within Pf1N1B4_2207 at 2520.054 kb on - strand, within Pf1N1B4_2207 at 2520.065 kb on + strand, within Pf1N1B4_2207 at 2520.065 kb on + strand, within Pf1N1B4_2207 at 2520.065 kb on + strand, within Pf1N1B4_2207 at 2520.077 kb on + strand, within Pf1N1B4_2207 at 2520.077 kb on + strand, within Pf1N1B4_2207 at 2520.077 kb on + strand, within Pf1N1B4_2207 at 2520.078 kb on - strand, within Pf1N1B4_2207 at 2520.080 kb on + strand, within Pf1N1B4_2207 at 2520.143 kb on + strand, within Pf1N1B4_2207 at 2520.143 kb on + strand, within Pf1N1B4_2207 at 2520.143 kb on + strand, within Pf1N1B4_2207 at 2520.144 kb on - strand, within Pf1N1B4_2207 at 2520.242 kb on + strand, within Pf1N1B4_2207 at 2520.242 kb on + strand, within Pf1N1B4_2207 at 2520.277 kb on + strand, within Pf1N1B4_2207 at 2520.277 kb on + strand, within Pf1N1B4_2207 at 2520.277 kb on + strand, within Pf1N1B4_2207 at 2520.278 kb on - strand, within Pf1N1B4_2207 at 2520.296 kb on + strand, within Pf1N1B4_2207 at 2520.296 kb on + strand, within Pf1N1B4_2207 at 2520.296 kb on + strand, within Pf1N1B4_2207 at 2520.296 kb on + strand, within Pf1N1B4_2207 at 2520.296 kb on + strand, within Pf1N1B4_2207 at 2520.296 kb on + strand, within Pf1N1B4_2207 at 2520.296 kb on + strand, within Pf1N1B4_2207 at 2520.314 kb on + strand, within Pf1N1B4_2207 at 2520.314 kb on + strand, within Pf1N1B4_2207 at 2520.314 kb on + strand, within Pf1N1B4_2207 at 2520.314 kb on + strand, within Pf1N1B4_2207 at 2520.314 kb on + strand, within Pf1N1B4_2207 at 2520.388 kb on + strand at 2520.419 kb on + strand at 2520.419 kb on + strand at 2520.419 kb on + strand at 2520.419 kb on + strand at 2520.419 kb on + strand at 2520.419 kb on + strand at 2520.419 kb on + strand at 2520.419 kb on + strand at 2520.420 kb on - strand at 2520.420 kb on - strand at 2520.420 kb on - strand at 2520.461 kb on + strand at 2520.461 kb on + strand at 2520.650 kb on + strand at 2520.650 kb on + strand at 2520.651 kb on - strand at 2520.651 kb on - strand at 2520.651 kb on - strand at 2520.651 kb on - strand at 2521.232 kb on + strand, within Pf1N1B4_2208 at 2521.232 kb on + strand, within Pf1N1B4_2208 at 2521.232 kb on + strand, within Pf1N1B4_2208 at 2521.232 kb on + strand, within Pf1N1B4_2208 at 2521.232 kb on + strand, within Pf1N1B4_2208 at 2521.233 kb on - strand, within Pf1N1B4_2208 at 2521.233 kb on - strand, within Pf1N1B4_2208 at 2521.460 kb on + strand, within Pf1N1B4_2208
Per-strain Table
Position Strand Gene LocusTag Fraction Rifampicin 0.004 mg/ml remove 2,518,466 + Pf1N1B4_2205 0.86 -1.0 2,518,466 + Pf1N1B4_2205 0.86 +0.7 2,518,466 + Pf1N1B4_2205 0.86 +1.4 2,518,467 - Pf1N1B4_2205 0.86 +0.1 2,518,535 + +1.6 2,518,535 + -0.9 2,518,535 + +0.1 2,518,535 + +0.2 2,518,535 + +0.8 2,518,535 + -0.7 2,518,535 + -0.3 2,518,536 - -0.3 2,518,536 - -0.7 2,518,536 - +1.0 2,518,536 - -0.7 2,518,573 + +1.3 2,518,574 - +0.3 2,518,600 + +0.1 2,518,600 + +1.3 2,518,601 - -0.5 2,518,608 + -0.3 2,518,609 - -0.4 2,518,636 + -1.5 2,518,636 + +0.6 2,518,637 - -0.1 2,518,637 - +0.4 2,518,637 - +0.5 2,518,686 + Pf1N1B4_2206 0.11 -2.5 2,518,686 + Pf1N1B4_2206 0.11 +0.8 2,518,686 + Pf1N1B4_2206 0.11 -0.1 2,518,686 + Pf1N1B4_2206 0.11 +1.8 2,518,687 - Pf1N1B4_2206 0.11 +0.9 2,518,687 - Pf1N1B4_2206 0.11 -1.1 2,518,687 - Pf1N1B4_2206 0.11 -0.3 2,518,749 - Pf1N1B4_2206 0.21 -2.2 2,518,779 + Pf1N1B4_2206 0.25 +1.1 2,518,779 + Pf1N1B4_2206 0.25 -0.3 2,518,779 + Pf1N1B4_2206 0.25 +2.2 2,518,779 + Pf1N1B4_2206 0.25 -1.0 2,518,780 - Pf1N1B4_2206 0.25 +0.3 2,518,780 - Pf1N1B4_2206 0.25 +1.1 2,518,780 - Pf1N1B4_2206 0.25 +1.3 2,518,828 - Pf1N1B4_2206 0.33 -1.1 2,518,888 - Pf1N1B4_2206 0.42 +1.4 2,518,888 - Pf1N1B4_2206 0.42 -1.9 2,518,993 + Pf1N1B4_2206 0.59 +0.3 2,518,994 - +1.3 2,518,994 - Pf1N1B4_2206 0.59 +1.0 2,519,076 + Pf1N1B4_2206 0.72 -1.3 2,519,076 + Pf1N1B4_2206 0.72 +0.8 2,519,077 - Pf1N1B4_2206 0.72 -0.9 2,519,097 + Pf1N1B4_2206 0.76 -0.1 2,519,097 + -1.1 2,519,097 + Pf1N1B4_2206 0.76 +0.0 2,519,097 + Pf1N1B4_2206 0.76 -1.3 2,519,097 + +0.3 2,519,098 - Pf1N1B4_2206 0.76 +0.8 2,519,098 - Pf1N1B4_2206 0.76 -1.2 2,519,098 - Pf1N1B4_2206 0.76 +1.4 2,519,098 - -0.7 2,519,126 + Pf1N1B4_2206 0.80 +1.7 2,519,126 + Pf1N1B4_2206 0.80 +0.7 2,519,127 - +0.5 2,519,127 - Pf1N1B4_2206 0.80 +0.4 2,519,142 + Pf1N1B4_2206 0.83 +1.9 2,519,142 + Pf1N1B4_2206 0.83 +0.9 2,519,142 + Pf1N1B4_2206 0.83 -0.9 2,519,143 - Pf1N1B4_2206 0.83 -0.3 2,519,143 - Pf1N1B4_2206 0.83 +1.3 2,519,143 - Pf1N1B4_2206 0.83 -0.3 2,519,285 - +0.6 2,519,341 + +0.0 2,519,342 - -0.5 2,519,342 - +2.6 2,519,394 + +1.5 2,519,395 - +1.8 2,519,405 + +0.5 2,519,405 + +1.3 2,519,405 + -0.1 2,519,405 + +1.3 2,519,405 + -0.5 2,519,405 + +0.3 2,519,405 + -1.4 2,519,405 + +0.5 2,519,405 + +3.7 2,519,405 + +0.0 2,519,405 + +0.1 2,519,405 + +0.9 2,519,405 + +2.3 2,519,406 - -0.1 2,519,406 - -0.7 2,519,406 - +1.9 2,519,406 - +0.6 2,519,406 - +2.9 2,519,406 - +0.5 2,519,407 + +1.0 2,519,407 + +1.1 2,519,407 + +0.3 2,519,407 + +2.9 2,519,407 + -2.3 2,519,407 + +0.5 2,519,407 + -0.7 2,519,407 + +0.3 2,519,407 + +2.1 2,519,407 + +1.9 2,519,407 + +2.5 2,519,407 + -0.3 2,519,407 + +1.0 2,519,407 + -0.1 2,519,407 + -0.1 2,519,408 - +0.5 2,519,408 - +1.6 2,519,408 - +0.8 2,519,408 - +1.1 2,519,544 + +1.4 2,519,544 + +2.8 2,519,544 + -0.3 2,519,544 + -0.1 2,519,545 - -0.5 2,519,822 - Pf1N1B4_2207 0.37 -0.2 2,519,848 + Pf1N1B4_2207 0.39 +0.5 2,519,888 + Pf1N1B4_2207 0.43 -0.3 2,519,888 + Pf1N1B4_2207 0.43 -0.9 2,519,888 + Pf1N1B4_2207 0.43 +0.9 2,519,888 + Pf1N1B4_2207 0.43 -0.7 2,519,906 - Pf1N1B4_2207 0.45 +0.7 2,519,924 - Pf1N1B4_2207 0.47 -0.9 2,520,053 + Pf1N1B4_2207 0.59 -1.3 2,520,054 - Pf1N1B4_2207 0.60 +0.7 2,520,054 - Pf1N1B4_2207 0.60 +0.1 2,520,065 + Pf1N1B4_2207 0.61 +0.7 2,520,065 + Pf1N1B4_2207 0.61 -1.1 2,520,065 + Pf1N1B4_2207 0.61 -0.1 2,520,077 + Pf1N1B4_2207 0.62 +1.9 2,520,077 + Pf1N1B4_2207 0.62 +0.1 2,520,077 + Pf1N1B4_2207 0.62 +2.3 2,520,078 - Pf1N1B4_2207 0.62 +1.1 2,520,080 + Pf1N1B4_2207 0.62 +0.6 2,520,143 + Pf1N1B4_2207 0.68 -0.3 2,520,143 + Pf1N1B4_2207 0.68 -0.7 2,520,143 + Pf1N1B4_2207 0.68 -0.3 2,520,144 - Pf1N1B4_2207 0.68 -0.7 2,520,242 + Pf1N1B4_2207 0.78 -1.1 2,520,242 + Pf1N1B4_2207 0.78 +0.1 2,520,277 + Pf1N1B4_2207 0.82 +1.3 2,520,277 + Pf1N1B4_2207 0.82 +0.8 2,520,277 + Pf1N1B4_2207 0.82 +0.7 2,520,278 - Pf1N1B4_2207 0.82 -1.9 2,520,296 + Pf1N1B4_2207 0.83 -1.2 2,520,296 + Pf1N1B4_2207 0.83 -0.7 2,520,296 + Pf1N1B4_2207 0.83 -0.7 2,520,296 + Pf1N1B4_2207 0.83 +0.1 2,520,296 + Pf1N1B4_2207 0.83 +1.3 2,520,296 + Pf1N1B4_2207 0.83 +0.4 2,520,296 + Pf1N1B4_2207 0.83 +1.0 2,520,314 + Pf1N1B4_2207 0.85 +1.3 2,520,314 + Pf1N1B4_2207 0.85 -0.2 2,520,314 + Pf1N1B4_2207 0.85 -0.7 2,520,314 + Pf1N1B4_2207 0.85 +0.7 2,520,314 + Pf1N1B4_2207 0.85 -1.3 2,520,388 + +0.1 2,520,419 + +0.1 2,520,419 + -0.1 2,520,419 + -0.5 2,520,419 + -0.1 2,520,419 + +1.0 2,520,419 + -1.9 2,520,419 + -1.1 2,520,419 + +0.4 2,520,420 - -1.1 2,520,420 - -1.1 2,520,420 - +0.3 2,520,461 + -1.2 2,520,461 + +0.7 2,520,650 + -0.3 2,520,650 + -2.2 2,520,651 - -1.5 2,520,651 - -0.5 2,520,651 - -2.1 2,520,651 - -1.5 2,521,232 + Pf1N1B4_2208 0.34 +0.7 2,521,232 + Pf1N1B4_2208 0.34 -0.3 2,521,232 + Pf1N1B4_2208 0.34 -1.4 2,521,232 + Pf1N1B4_2208 0.34 -1.1 2,521,232 + Pf1N1B4_2208 0.34 -0.3 2,521,233 - Pf1N1B4_2208 0.34 +2.1 2,521,233 - Pf1N1B4_2208 0.34 -1.6 2,521,460 + Pf1N1B4_2208 0.44 -1.5
Or see this region's nucleotide sequence