Experiment: Doxycycline hyclate 0.0001 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_5656 and Pf1N1B4_5657 overlap by 4 nucleotides Pf1N1B4_5657 and Pf1N1B4_5658 are separated by 82 nucleotides Pf1N1B4_5658 and Pf1N1B4_5659 are separated by 183 nucleotides Pf1N1B4_5659 and Pf1N1B4_5660 are separated by 213 nucleotides
Pf1N1B4_5656 - Predicted cobalt transporter CbtA, at 87,675 to 88,382
_5656
Pf1N1B4_5657 - Cobalt-precorrin-3b C17-methyltransferase, at 88,379 to 88,792
_5657
Pf1N1B4_5658 - Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133), at 88,875 to 89,621
_5658
Pf1N1B4_5659 - NfuA Fe-S protein maturation, at 89,805 to 90,389
_5659
Pf1N1B4_5660 - cis/trans isomerase, at 90,603 to 92,888
_5660
Position (kb)
88
89
90 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 87.986 kb on + strand at 87.986 kb on + strand, within Pf1N1B4_5656 at 88.372 kb on - strand at 88.884 kb on + strand at 88.885 kb on - strand at 88.968 kb on + strand, within Pf1N1B4_5658 at 88.968 kb on + strand, within Pf1N1B4_5658 at 88.968 kb on + strand, within Pf1N1B4_5658 at 88.968 kb on + strand, within Pf1N1B4_5658 at 88.968 kb on + strand, within Pf1N1B4_5658 at 88.969 kb on - strand at 88.969 kb on - strand, within Pf1N1B4_5658 at 88.969 kb on - strand, within Pf1N1B4_5658 at 88.969 kb on - strand, within Pf1N1B4_5658 at 88.969 kb on - strand, within Pf1N1B4_5658 at 88.997 kb on - strand, within Pf1N1B4_5658 at 89.131 kb on - strand, within Pf1N1B4_5658 at 89.586 kb on + strand at 89.807 kb on - strand at 89.809 kb on + strand at 89.809 kb on + strand at 89.809 kb on + strand at 89.809 kb on + strand at 89.809 kb on + strand at 89.809 kb on + strand at 89.810 kb on - strand at 89.810 kb on - strand at 89.810 kb on - strand at 89.810 kb on - strand at 89.810 kb on - strand at 89.812 kb on + strand at 89.813 kb on - strand at 89.871 kb on - strand, within Pf1N1B4_5659 at 89.871 kb on - strand, within Pf1N1B4_5659 at 89.871 kb on - strand, within Pf1N1B4_5659 at 89.871 kb on - strand, within Pf1N1B4_5659 at 89.871 kb on - strand, within Pf1N1B4_5659 at 89.871 kb on - strand, within Pf1N1B4_5659 at 89.871 kb on - strand, within Pf1N1B4_5659 at 90.040 kb on + strand, within Pf1N1B4_5659 at 90.040 kb on + strand, within Pf1N1B4_5659 at 90.040 kb on + strand, within Pf1N1B4_5659 at 90.040 kb on + strand, within Pf1N1B4_5659 at 90.040 kb on + strand, within Pf1N1B4_5659 at 90.041 kb on - strand, within Pf1N1B4_5659 at 90.041 kb on - strand, within Pf1N1B4_5659 at 90.041 kb on - strand, within Pf1N1B4_5659 at 90.041 kb on - strand, within Pf1N1B4_5659 at 90.041 kb on - strand, within Pf1N1B4_5659 at 90.041 kb on - strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.043 kb on + strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.044 kb on - strand, within Pf1N1B4_5659 at 90.087 kb on + strand, within Pf1N1B4_5659 at 90.087 kb on + strand, within Pf1N1B4_5659 at 90.088 kb on - strand, within Pf1N1B4_5659 at 90.088 kb on - strand, within Pf1N1B4_5659 at 90.088 kb on - strand, within Pf1N1B4_5659 at 90.088 kb on - strand, within Pf1N1B4_5659 at 90.088 kb on - strand, within Pf1N1B4_5659 at 90.142 kb on + strand, within Pf1N1B4_5659 at 90.190 kb on + strand, within Pf1N1B4_5659 at 90.190 kb on + strand, within Pf1N1B4_5659 at 90.190 kb on + strand, within Pf1N1B4_5659 at 90.190 kb on + strand, within Pf1N1B4_5659 at 90.191 kb on - strand, within Pf1N1B4_5659 at 90.191 kb on - strand, within Pf1N1B4_5659 at 90.191 kb on - strand, within Pf1N1B4_5659 at 90.191 kb on - strand at 90.191 kb on - strand, within Pf1N1B4_5659 at 90.191 kb on - strand, within Pf1N1B4_5659 at 90.253 kb on + strand, within Pf1N1B4_5659 at 90.254 kb on - strand, within Pf1N1B4_5659 at 90.274 kb on + strand, within Pf1N1B4_5659 at 90.296 kb on + strand, within Pf1N1B4_5659 at 90.296 kb on + strand, within Pf1N1B4_5659 at 90.296 kb on + strand, within Pf1N1B4_5659 at 90.296 kb on + strand, within Pf1N1B4_5659 at 90.297 kb on - strand, within Pf1N1B4_5659 at 90.352 kb on + strand at 90.353 kb on - strand at 90.353 kb on - strand at 90.353 kb on - strand at 90.377 kb on + strand at 90.377 kb on + strand at 90.377 kb on + strand at 90.377 kb on + strand at 90.378 kb on - strand at 90.378 kb on - strand at 90.378 kb on - strand at 90.378 kb on - strand at 90.378 kb on - strand at 90.378 kb on - strand at 90.378 kb on - strand at 90.378 kb on - strand at 90.380 kb on + strand at 90.380 kb on + strand at 90.381 kb on - strand at 90.419 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction Doxycycline hyclate 0.0001 mg/ml remove 87,986 + -0.7 87,986 + Pf1N1B4_5656 0.44 -0.1 88,372 - -0.8 88,884 + -0.1 88,885 - +0.9 88,968 + Pf1N1B4_5658 0.12 -0.1 88,968 + Pf1N1B4_5658 0.12 +0.9 88,968 + Pf1N1B4_5658 0.12 -1.1 88,968 + Pf1N1B4_5658 0.12 -2.1 88,968 + Pf1N1B4_5658 0.12 +2.9 88,969 - -0.7 88,969 - Pf1N1B4_5658 0.13 +0.9 88,969 - Pf1N1B4_5658 0.13 -1.7 88,969 - Pf1N1B4_5658 0.13 +1.1 88,969 - Pf1N1B4_5658 0.13 +2.5 88,997 - Pf1N1B4_5658 0.16 -0.0 89,131 - Pf1N1B4_5658 0.34 -0.7 89,586 + -0.4 89,807 - +0.2 89,809 + +0.1 89,809 + -0.1 89,809 + -0.3 89,809 + -0.1 89,809 + +1.6 89,809 + +0.9 89,810 - +3.5 89,810 - +0.4 89,810 - -0.1 89,810 - +0.8 89,810 - +0.6 89,812 + -0.4 89,813 - +1.0 89,871 - Pf1N1B4_5659 0.11 +1.7 89,871 - Pf1N1B4_5659 0.11 +2.1 89,871 - Pf1N1B4_5659 0.11 +0.9 89,871 - Pf1N1B4_5659 0.11 +1.0 89,871 - Pf1N1B4_5659 0.11 +1.4 89,871 - Pf1N1B4_5659 0.11 +1.9 89,871 - Pf1N1B4_5659 0.11 +0.9 90,040 + Pf1N1B4_5659 0.40 +0.7 90,040 + Pf1N1B4_5659 0.40 +1.8 90,040 + Pf1N1B4_5659 0.40 +2.2 90,040 + Pf1N1B4_5659 0.40 +1.5 90,040 + Pf1N1B4_5659 0.40 -1.3 90,041 - Pf1N1B4_5659 0.40 +2.8 90,041 - Pf1N1B4_5659 0.40 +2.5 90,041 - Pf1N1B4_5659 0.40 +0.3 90,041 - Pf1N1B4_5659 0.40 +2.0 90,041 - Pf1N1B4_5659 0.40 +1.9 90,041 - Pf1N1B4_5659 0.40 +2.3 90,043 + Pf1N1B4_5659 0.41 +3.1 90,043 + Pf1N1B4_5659 0.41 +1.8 90,043 + Pf1N1B4_5659 0.41 +1.7 90,043 + Pf1N1B4_5659 0.41 +1.6 90,043 + Pf1N1B4_5659 0.41 +2.2 90,043 + Pf1N1B4_5659 0.41 +2.1 90,043 + Pf1N1B4_5659 0.41 +2.1 90,043 + Pf1N1B4_5659 0.41 -0.4 90,043 + Pf1N1B4_5659 0.41 +1.6 90,044 - Pf1N1B4_5659 0.41 +0.5 90,044 - Pf1N1B4_5659 0.41 +2.4 90,044 - Pf1N1B4_5659 0.41 +2.2 90,044 - Pf1N1B4_5659 0.41 +2.1 90,044 - Pf1N1B4_5659 0.41 +1.6 90,044 - Pf1N1B4_5659 0.41 +0.6 90,044 - Pf1N1B4_5659 0.41 +2.9 90,044 - Pf1N1B4_5659 0.41 +1.8 90,044 - Pf1N1B4_5659 0.41 +3.2 90,044 - Pf1N1B4_5659 0.41 +1.5 90,044 - Pf1N1B4_5659 0.41 +2.5 90,044 - Pf1N1B4_5659 0.41 +1.6 90,044 - Pf1N1B4_5659 0.41 +1.9 90,044 - Pf1N1B4_5659 0.41 +1.4 90,087 + Pf1N1B4_5659 0.48 +1.0 90,087 + Pf1N1B4_5659 0.48 +0.5 90,088 - Pf1N1B4_5659 0.48 +3.6 90,088 - Pf1N1B4_5659 0.48 +1.8 90,088 - Pf1N1B4_5659 0.48 +2.7 90,088 - Pf1N1B4_5659 0.48 +1.5 90,088 - Pf1N1B4_5659 0.48 +2.7 90,142 + Pf1N1B4_5659 0.58 +1.8 90,190 + Pf1N1B4_5659 0.66 +3.0 90,190 + Pf1N1B4_5659 0.66 +2.2 90,190 + Pf1N1B4_5659 0.66 +2.1 90,190 + Pf1N1B4_5659 0.66 +1.9 90,191 - Pf1N1B4_5659 0.66 +1.9 90,191 - Pf1N1B4_5659 0.66 +1.0 90,191 - Pf1N1B4_5659 0.66 +0.9 90,191 - +1.5 90,191 - Pf1N1B4_5659 0.66 +2.3 90,191 - Pf1N1B4_5659 0.66 +2.0 90,253 + Pf1N1B4_5659 0.77 -1.1 90,254 - Pf1N1B4_5659 0.77 +0.9 90,274 + Pf1N1B4_5659 0.80 +1.9 90,296 + Pf1N1B4_5659 0.84 +2.3 90,296 + Pf1N1B4_5659 0.84 +2.4 90,296 + Pf1N1B4_5659 0.84 -1.1 90,296 + Pf1N1B4_5659 0.84 +2.7 90,297 - Pf1N1B4_5659 0.84 +2.0 90,352 + +3.0 90,353 - +1.6 90,353 - +2.5 90,353 - +1.9 90,377 + +2.1 90,377 + +1.1 90,377 + -0.1 90,377 + +1.5 90,378 - +0.6 90,378 - +0.6 90,378 - +2.2 90,378 - +2.6 90,378 - +1.2 90,378 - +2.4 90,378 - +1.3 90,378 - +1.9 90,380 + -1.5 90,380 + +1.7 90,381 - +1.9 90,419 + +0.4
Or see this region's nucleotide sequence