Experiment: K. M5a1 KLEB23 MOI 10
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt BWI76_RS14770 and BWI76_RS14775 overlap by 8 nucleotides BWI76_RS14775 and BWI76_RS14780 are separated by 9 nucleotides BWI76_RS14780 and BWI76_RS14785 are separated by 435 nucleotides BWI76_RS14785 and BWI76_RS14790 are separated by 36 nucleotides
BWI76_RS14770: BWI76_RS14770 - PTS IIA 2 domain protein, at 3,098,331 to 3,098,774
_RS14770
BWI76_RS14775: BWI76_RS14775 - creatinine amidohydrolase, at 3,098,767 to 3,099,507
_RS14775
BWI76_RS14780: BWI76_RS14780 - phosphotriesterase, at 3,099,517 to 3,100,488
_RS14780
BWI76_RS14785: BWI76_RS14785 - hypothetical protein, at 3,100,924 to 3,101,172
_RS14785
BWI76_RS14790: BWI76_RS14790 - 2-dehydropantoate 2-reductase, at 3,101,209 to 3,102,102
_RS14790
Position (kb)
3099
3100
3101 Strain fitness (log2 ratio)
-2
-1
0
1
2
3
4 at 3098.731 kb on - strand at 3098.906 kb on + strand, within BWI76_RS14775 at 3099.126 kb on + strand at 3099.191 kb on + strand, within BWI76_RS14775 at 3099.743 kb on + strand, within BWI76_RS14780 at 3100.077 kb on + strand, within BWI76_RS14780 at 3100.176 kb on - strand, within BWI76_RS14780 at 3100.627 kb on + strand at 3101.321 kb on - strand at 3101.463 kb on + strand, within BWI76_RS14790
Per-strain Table
Position Strand Gene LocusTag Fraction K. M5a1 KLEB23 MOI 10 remove 3,098,731 - -2.6 3,098,906 + BWI76_RS14775 0.19 -2.0 3,099,126 + +3.9 3,099,191 + BWI76_RS14775 0.57 +0.2 3,099,743 + BWI76_RS14780 0.23 -1.3 3,100,077 + BWI76_RS14780 0.58 -0.2 3,100,176 - BWI76_RS14780 0.68 +0.0 3,100,627 + -0.1 3,101,321 - +0.5 3,101,463 + BWI76_RS14790 0.28 +2.5
Or see this region's nucleotide sequence