Strain Fitness in Klebsiella michiganensis M5al around BWI76_RS20110

Experiment: KLEB17 MOI 1

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntBWI76_RS20105 and BWI76_RS20110 are separated by 19 nucleotidesBWI76_RS20110 and BWI76_RS20115 are separated by 30 nucleotidesBWI76_RS20115 and BWI76_RS20120 are separated by 62 nucleotides BWI76_RS20105: BWI76_RS20105 - fimbrial protein, at 4,210,912 to 4,211,955 _RS20105 BWI76_RS20110: BWI76_RS20110 - fimbrial assembly protein, at 4,211,975 to 4,214,524 _RS20110 BWI76_RS20115: BWI76_RS20115 - hypothetical protein, at 4,214,555 to 4,215,217 _RS20115 BWI76_RS20120: BWI76_RS20120 - fimbrial protein, at 4,215,280 to 4,215,807 _RS20120 Position (kb) 4211 4212 4213 4214 4215Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2 3 4 5at 4211.001 kb on - strandat 4211.003 kb on - strandat 4211.005 kb on + strandat 4211.005 kb on + strandat 4211.019 kb on + strand, within BWI76_RS20105at 4211.022 kb on - strand, within BWI76_RS20105at 4211.029 kb on + strand, within BWI76_RS20105at 4211.039 kb on + strand, within BWI76_RS20105at 4211.039 kb on + strand, within BWI76_RS20105at 4211.039 kb on + strand, within BWI76_RS20105at 4211.047 kb on - strand, within BWI76_RS20105at 4211.047 kb on - strand, within BWI76_RS20105at 4211.047 kb on - strand, within BWI76_RS20105at 4211.057 kb on - strand, within BWI76_RS20105at 4211.059 kb on - strandat 4211.084 kb on - strand, within BWI76_RS20105at 4211.106 kb on + strand, within BWI76_RS20105at 4211.114 kb on + strand, within BWI76_RS20105at 4211.114 kb on + strand, within BWI76_RS20105at 4211.114 kb on + strand, within BWI76_RS20105at 4211.114 kb on + strand, within BWI76_RS20105at 4211.122 kb on - strand, within BWI76_RS20105at 4211.122 kb on - strand, within BWI76_RS20105at 4211.122 kb on - strand, within BWI76_RS20105at 4211.122 kb on - strand, within BWI76_RS20105at 4211.124 kb on + strand, within BWI76_RS20105at 4211.129 kb on + strand, within BWI76_RS20105at 4211.129 kb on + strand, within BWI76_RS20105at 4211.129 kb on + strand, within BWI76_RS20105at 4211.129 kb on + strand, within BWI76_RS20105at 4211.129 kb on + strand, within BWI76_RS20105at 4211.129 kb on + strand, within BWI76_RS20105at 4211.129 kb on - strand, within BWI76_RS20105at 4211.132 kb on - strand, within BWI76_RS20105at 4211.137 kb on - strandat 4211.137 kb on - strand, within BWI76_RS20105at 4211.137 kb on - strand, within BWI76_RS20105at 4211.139 kb on - strand, within BWI76_RS20105at 4211.139 kb on - strand, within BWI76_RS20105at 4211.139 kb on - strand, within BWI76_RS20105at 4211.139 kb on - strand, within BWI76_RS20105at 4211.141 kb on - strand, within BWI76_RS20105at 4211.142 kb on + strand, within BWI76_RS20105at 4211.157 kb on + strand, within BWI76_RS20105at 4211.160 kb on - strand, within BWI76_RS20105at 4211.162 kb on - strand, within BWI76_RS20105at 4211.162 kb on - strand, within BWI76_RS20105at 4211.179 kb on - strandat 4211.198 kb on - strand, within BWI76_RS20105at 4211.200 kb on + strand, within BWI76_RS20105at 4211.211 kb on + strand, within BWI76_RS20105at 4211.217 kb on + strand, within BWI76_RS20105at 4211.217 kb on - strand, within BWI76_RS20105at 4211.217 kb on - strand, within BWI76_RS20105at 4211.220 kb on + strand, within BWI76_RS20105at 4211.225 kb on + strand, within BWI76_RS20105at 4211.233 kb on - strand, within BWI76_RS20105at 4211.237 kb on + strand, within BWI76_RS20105at 4211.245 kb on - strand, within BWI76_RS20105at 4211.323 kb on + strand, within BWI76_RS20105at 4211.326 kb on + strand, within BWI76_RS20105at 4211.334 kb on - strand, within BWI76_RS20105at 4211.334 kb on - strand, within BWI76_RS20105at 4211.334 kb on - strand, within BWI76_RS20105at 4211.337 kb on + strand, within BWI76_RS20105at 4211.345 kb on - strand, within BWI76_RS20105at 4211.345 kb on - strand, within BWI76_RS20105at 4211.361 kb on + strand, within BWI76_RS20105at 4211.370 kb on + strand, within BWI76_RS20105at 4211.370 kb on + strand, within BWI76_RS20105at 4211.370 kb on + strand, within BWI76_RS20105at 4211.370 kb on + strand, within BWI76_RS20105at 4211.370 kb on + strand, within BWI76_RS20105at 4211.378 kb on - strand, within BWI76_RS20105at 4211.378 kb on - strand, within BWI76_RS20105at 4211.378 kb on - strand, within BWI76_RS20105at 4211.378 kb on - strand, within BWI76_RS20105at 4211.378 kb on - strand, within BWI76_RS20105at 4211.378 kb on - strand, within BWI76_RS20105at 4211.401 kb on + strand, within BWI76_RS20105at 4211.408 kb on + strand, within BWI76_RS20105at 4211.409 kb on + strand, within BWI76_RS20105at 4211.409 kb on - strand, within BWI76_RS20105at 4211.416 kb on - strand, within BWI76_RS20105at 4211.417 kb on - strandat 4211.417 kb on - strand, within BWI76_RS20105at 4211.427 kb on + strand, within BWI76_RS20105at 4211.431 kb on + strand, within BWI76_RS20105at 4211.437 kb on + strand, within BWI76_RS20105at 4211.473 kb on + strand, within BWI76_RS20105at 4211.481 kb on + strand, within BWI76_RS20105at 4211.481 kb on + strand, within BWI76_RS20105at 4211.489 kb on - strand, within BWI76_RS20105at 4211.489 kb on - strand, within BWI76_RS20105at 4211.489 kb on - strand, within BWI76_RS20105at 4211.527 kb on + strand, within BWI76_RS20105at 4211.527 kb on + strand, within BWI76_RS20105at 4211.535 kb on - strand, within BWI76_RS20105at 4211.562 kb on - strand, within BWI76_RS20105at 4211.580 kb on - strand, within BWI76_RS20105at 4211.602 kb on - strand, within BWI76_RS20105at 4211.602 kb on - strand, within BWI76_RS20105at 4211.651 kb on + strand, within BWI76_RS20105at 4211.659 kb on - strandat 4211.708 kb on + strand, within BWI76_RS20105at 4211.716 kb on - strand, within BWI76_RS20105at 4211.717 kb on - strand, within BWI76_RS20105at 4211.762 kb on + strand, within BWI76_RS20105at 4211.762 kb on + strand, within BWI76_RS20105at 4211.764 kb on + strand, within BWI76_RS20105at 4211.777 kb on - strand, within BWI76_RS20105at 4211.779 kb on + strand, within BWI76_RS20105at 4211.789 kb on + strand, within BWI76_RS20105at 4211.797 kb on - strand, within BWI76_RS20105at 4211.797 kb on - strand, within BWI76_RS20105at 4211.816 kb on - strandat 4211.857 kb on + strandat 4211.857 kb on + strandat 4211.871 kb on + strandat 4211.875 kb on + strandat 4211.877 kb on + strandat 4211.976 kb on - strandat 4211.981 kb on + strandat 4211.981 kb on + strandat 4211.986 kb on + strandat 4211.989 kb on - strandat 4212.026 kb on + strandat 4212.058 kb on - strandat 4212.063 kb on - strandat 4212.063 kb on - strandat 4212.162 kb on + strandat 4212.212 kb on - strandat 4212.346 kb on - strand, within BWI76_RS20110at 4212.346 kb on - strand, within BWI76_RS20110at 4212.383 kb on - strand, within BWI76_RS20110at 4212.455 kb on - strand, within BWI76_RS20110at 4212.515 kb on + strand, within BWI76_RS20110at 4212.522 kb on + strand, within BWI76_RS20110at 4212.523 kb on - strand, within BWI76_RS20110at 4212.661 kb on + strand, within BWI76_RS20110at 4212.762 kb on - strand, within BWI76_RS20110at 4212.798 kb on + strand, within BWI76_RS20110at 4212.810 kb on + strand, within BWI76_RS20110at 4213.014 kb on - strand, within BWI76_RS20110at 4213.165 kb on - strand, within BWI76_RS20110at 4213.216 kb on - strand, within BWI76_RS20110at 4213.227 kb on + strand, within BWI76_RS20110at 4213.232 kb on + strand, within BWI76_RS20110at 4213.285 kb on + strand, within BWI76_RS20110at 4213.311 kb on - strand, within BWI76_RS20110at 4213.420 kb on + strand, within BWI76_RS20110at 4213.669 kb on + strand, within BWI76_RS20110at 4213.828 kb on - strand, within BWI76_RS20110at 4214.046 kb on + strand, within BWI76_RS20110at 4214.046 kb on + strand, within BWI76_RS20110at 4214.046 kb on + strand, within BWI76_RS20110at 4214.157 kb on - strand, within BWI76_RS20110at 4214.334 kb on + strandat 4214.445 kb on + strandat 4214.453 kb on - strandat 4214.536 kb on - strandat 4214.545 kb on - strandat 4214.550 kb on - strandat 4214.573 kb on - strandat 4214.628 kb on - strand, within BWI76_RS20115at 4214.880 kb on + strand, within BWI76_RS20115at 4214.880 kb on + strand, within BWI76_RS20115at 4214.888 kb on - strandat 4215.066 kb on - strand, within BWI76_RS20115at 4215.070 kb on + strand, within BWI76_RS20115at 4215.402 kb on + strand, within BWI76_RS20120at 4215.414 kb on - strand, within BWI76_RS20120at 4215.479 kb on + strand, within BWI76_RS20120at 4215.487 kb on - strand, within BWI76_RS20120

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Per-strain Table

Position Strand Gene LocusTag Fraction KLEB17 MOI 1
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4,211,001 - -0.3
4,211,003 - -1.1
4,211,005 + -1.7
4,211,005 + -1.6
4,211,019 + BWI76_RS20105 0.10 -0.4
4,211,022 - BWI76_RS20105 0.11 -2.7
4,211,029 + BWI76_RS20105 0.11 +1.2
4,211,039 + BWI76_RS20105 0.12 +1.9
4,211,039 + BWI76_RS20105 0.12 +0.9
4,211,039 + BWI76_RS20105 0.12 +1.4
4,211,047 - BWI76_RS20105 0.13 -1.7
4,211,047 - BWI76_RS20105 0.13 +0.7
4,211,047 - BWI76_RS20105 0.13 +2.0
4,211,057 - BWI76_RS20105 0.14 -2.4
4,211,059 - +1.9
4,211,084 - BWI76_RS20105 0.16 +1.5
4,211,106 + BWI76_RS20105 0.19 -0.7
4,211,114 + BWI76_RS20105 0.19 -1.0
4,211,114 + BWI76_RS20105 0.19 +1.1
4,211,114 + BWI76_RS20105 0.19 -1.8
4,211,114 + BWI76_RS20105 0.19 -0.8
4,211,122 - BWI76_RS20105 0.20 +0.1
4,211,122 - BWI76_RS20105 0.20 -1.6
4,211,122 - BWI76_RS20105 0.20 +0.1
4,211,122 - BWI76_RS20105 0.20 -1.4
4,211,124 + BWI76_RS20105 0.20 -1.8
4,211,129 + BWI76_RS20105 0.21 -0.7
4,211,129 + BWI76_RS20105 0.21 -1.3
4,211,129 + BWI76_RS20105 0.21 -3.4
4,211,129 + BWI76_RS20105 0.21 -2.7
4,211,129 + BWI76_RS20105 0.21 +1.9
4,211,129 + BWI76_RS20105 0.21 +0.2
4,211,129 - BWI76_RS20105 0.21 +0.3
4,211,132 - BWI76_RS20105 0.21 +0.1
4,211,137 - +1.9
4,211,137 - BWI76_RS20105 0.22 +2.7
4,211,137 - BWI76_RS20105 0.22 -4.1
4,211,139 - BWI76_RS20105 0.22 -2.2
4,211,139 - BWI76_RS20105 0.22 -1.1
4,211,139 - BWI76_RS20105 0.22 +0.3
4,211,139 - BWI76_RS20105 0.22 +1.9
4,211,141 - BWI76_RS20105 0.22 -1.2
4,211,142 + BWI76_RS20105 0.22 -4.3
4,211,157 + BWI76_RS20105 0.23 +0.3
4,211,160 - BWI76_RS20105 0.24 -2.4
4,211,162 - BWI76_RS20105 0.24 -0.8
4,211,162 - BWI76_RS20105 0.24 -0.7
4,211,179 - +1.9
4,211,198 - BWI76_RS20105 0.27 -1.6
4,211,200 + BWI76_RS20105 0.28 -3.1
4,211,211 + BWI76_RS20105 0.29 +0.3
4,211,217 + BWI76_RS20105 0.29 +0.2
4,211,217 - BWI76_RS20105 0.29 +0.2
4,211,217 - BWI76_RS20105 0.29 +0.9
4,211,220 + BWI76_RS20105 0.30 +1.4
4,211,225 + BWI76_RS20105 0.30 -0.0
4,211,233 - BWI76_RS20105 0.31 -0.1
4,211,237 + BWI76_RS20105 0.31 -0.1
4,211,245 - BWI76_RS20105 0.32 -2.6
4,211,323 + BWI76_RS20105 0.39 +3.3
4,211,326 + BWI76_RS20105 0.40 -0.7
4,211,334 - BWI76_RS20105 0.40 -2.3
4,211,334 - BWI76_RS20105 0.40 -2.7
4,211,334 - BWI76_RS20105 0.40 +1.2
4,211,337 + BWI76_RS20105 0.41 -1.7
4,211,345 - BWI76_RS20105 0.41 +2.2
4,211,345 - BWI76_RS20105 0.41 -1.9
4,211,361 + BWI76_RS20105 0.43 -0.7
4,211,370 + BWI76_RS20105 0.44 +1.9
4,211,370 + BWI76_RS20105 0.44 -1.4
4,211,370 + BWI76_RS20105 0.44 +1.9
4,211,370 + BWI76_RS20105 0.44 +3.9
4,211,370 + BWI76_RS20105 0.44 -1.4
4,211,378 - BWI76_RS20105 0.45 -0.4
4,211,378 - BWI76_RS20105 0.45 -3.3
4,211,378 - BWI76_RS20105 0.45 +1.1
4,211,378 - BWI76_RS20105 0.45 -0.1
4,211,378 - BWI76_RS20105 0.45 +0.9
4,211,378 - BWI76_RS20105 0.45 -1.8
4,211,401 + BWI76_RS20105 0.47 -0.1
4,211,408 + BWI76_RS20105 0.48 +1.9
4,211,409 + BWI76_RS20105 0.48 +0.1
4,211,409 - BWI76_RS20105 0.48 +1.9
4,211,416 - BWI76_RS20105 0.48 -0.7
4,211,417 - +1.9
4,211,417 - BWI76_RS20105 0.48 +1.9
4,211,427 + BWI76_RS20105 0.49 +1.3
4,211,431 + BWI76_RS20105 0.50 +2.9
4,211,437 + BWI76_RS20105 0.50 -0.2
4,211,473 + BWI76_RS20105 0.54 +1.0
4,211,481 + BWI76_RS20105 0.55 +0.3
4,211,481 + BWI76_RS20105 0.55 +3.1
4,211,489 - BWI76_RS20105 0.55 -2.9
4,211,489 - BWI76_RS20105 0.55 -2.2
4,211,489 - BWI76_RS20105 0.55 -1.1
4,211,527 + BWI76_RS20105 0.59 -1.3
4,211,527 + BWI76_RS20105 0.59 -1.3
4,211,535 - BWI76_RS20105 0.60 +2.6
4,211,562 - BWI76_RS20105 0.62 +2.6
4,211,580 - BWI76_RS20105 0.64 +1.1
4,211,602 - BWI76_RS20105 0.66 -2.2
4,211,602 - BWI76_RS20105 0.66 +3.9
4,211,651 + BWI76_RS20105 0.71 +0.7
4,211,659 - +0.9
4,211,708 + BWI76_RS20105 0.76 -1.2
4,211,716 - BWI76_RS20105 0.77 +3.5
4,211,717 - BWI76_RS20105 0.77 -2.0
4,211,762 + BWI76_RS20105 0.81 +1.9
4,211,762 + BWI76_RS20105 0.81 +1.7
4,211,764 + BWI76_RS20105 0.82 +0.8
4,211,777 - BWI76_RS20105 0.83 +0.0
4,211,779 + BWI76_RS20105 0.83 -0.4
4,211,789 + BWI76_RS20105 0.84 -1.4
4,211,797 - BWI76_RS20105 0.85 +0.0
4,211,797 - BWI76_RS20105 0.85 -0.1
4,211,816 - -0.4
4,211,857 + +1.0
4,211,857 + -1.8
4,211,871 + -1.6
4,211,875 + -0.4
4,211,877 + +0.2
4,211,976 - +1.1
4,211,981 + -1.2
4,211,981 + -1.7
4,211,986 + +0.9
4,211,989 - +0.6
4,212,026 + -0.7
4,212,058 - +0.0
4,212,063 - -1.5
4,212,063 - +0.5
4,212,162 + -0.3
4,212,212 - -3.4
4,212,346 - BWI76_RS20110 0.15 -3.9
4,212,346 - BWI76_RS20110 0.15 -0.9
4,212,383 - BWI76_RS20110 0.16 -1.1
4,212,455 - BWI76_RS20110 0.19 -2.0
4,212,515 + BWI76_RS20110 0.21 -1.6
4,212,522 + BWI76_RS20110 0.21 -0.1
4,212,523 - BWI76_RS20110 0.21 -0.0
4,212,661 + BWI76_RS20110 0.27 +0.6
4,212,762 - BWI76_RS20110 0.31 -0.5
4,212,798 + BWI76_RS20110 0.32 -0.9
4,212,810 + BWI76_RS20110 0.33 -0.8
4,213,014 - BWI76_RS20110 0.41 -0.0
4,213,165 - BWI76_RS20110 0.47 -1.1
4,213,216 - BWI76_RS20110 0.49 -0.9
4,213,227 + BWI76_RS20110 0.49 +0.1
4,213,232 + BWI76_RS20110 0.49 -0.1
4,213,285 + BWI76_RS20110 0.51 -2.0
4,213,311 - BWI76_RS20110 0.52 +1.0
4,213,420 + BWI76_RS20110 0.57 -1.0
4,213,669 + BWI76_RS20110 0.66 -2.2
4,213,828 - BWI76_RS20110 0.73 -0.3
4,214,046 + BWI76_RS20110 0.81 +1.1
4,214,046 + BWI76_RS20110 0.81 +0.3
4,214,046 + BWI76_RS20110 0.81 +5.0
4,214,157 - BWI76_RS20110 0.86 -0.5
4,214,334 + -1.7
4,214,445 + -1.6
4,214,453 - +0.9
4,214,536 - -3.0
4,214,545 - +1.0
4,214,550 - +1.1
4,214,573 - +0.6
4,214,628 - BWI76_RS20115 0.11 -0.8
4,214,880 + BWI76_RS20115 0.49 +1.4
4,214,880 + BWI76_RS20115 0.49 +0.7
4,214,888 - +0.3
4,215,066 - BWI76_RS20115 0.77 -0.1
4,215,070 + BWI76_RS20115 0.78 +0.9
4,215,402 + BWI76_RS20120 0.23 +0.6
4,215,414 - BWI76_RS20120 0.25 +1.2
4,215,479 + BWI76_RS20120 0.38 -0.9
4,215,487 - BWI76_RS20120 0.39 -1.0

Or see this region's nucleotide sequence