Experiment: KLEB15 MOI 10
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt BWI76_RS12395 and BWI76_RS12400 are separated by 59 nucleotides BWI76_RS12400 and BWI76_RS12405 are separated by 509 nucleotides
BWI76_RS12395: BWI76_RS12395 - zinc-binding alcohol dehydrogenase, at 2,588,918 to 2,589,901
_RS12395
BWI76_RS12400: BWI76_RS12400 - TetR family transcriptional regulator, at 2,589,961 to 2,590,617
_RS12400
BWI76_RS12405: BWI76_RS12405 - diguanylate phosphodiesterase, at 2,591,127 to 2,592,299
_RS12405
Position (kb)
2589
2590
2591 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3
4
5 at 2588.994 kb on - strand at 2589.188 kb on - strand, within BWI76_RS12395 at 2589.353 kb on + strand, within BWI76_RS12395 at 2589.381 kb on - strand, within BWI76_RS12395 at 2589.495 kb on + strand, within BWI76_RS12395 at 2589.581 kb on + strand, within BWI76_RS12395 at 2589.605 kb on + strand, within BWI76_RS12395 at 2589.660 kb on + strand, within BWI76_RS12395 at 2589.660 kb on + strand, within BWI76_RS12395 at 2589.660 kb on + strand, within BWI76_RS12395 at 2589.661 kb on - strand, within BWI76_RS12395 at 2589.668 kb on - strand, within BWI76_RS12395 at 2589.678 kb on - strand, within BWI76_RS12395 at 2589.687 kb on + strand, within BWI76_RS12395 at 2589.702 kb on + strand, within BWI76_RS12395 at 2589.708 kb on + strand, within BWI76_RS12395 at 2589.718 kb on + strand, within BWI76_RS12395 at 2589.750 kb on + strand, within BWI76_RS12395 at 2589.781 kb on - strand, within BWI76_RS12395 at 2589.789 kb on + strand, within BWI76_RS12395 at 2589.790 kb on + strand, within BWI76_RS12395 at 2589.797 kb on - strand, within BWI76_RS12395 at 2589.805 kb on + strand at 2589.807 kb on - strand at 2589.810 kb on + strand at 2589.813 kb on + strand at 2589.813 kb on - strand at 2589.815 kb on + strand at 2589.815 kb on - strand at 2589.822 kb on - strand at 2589.834 kb on + strand at 2589.854 kb on + strand at 2589.910 kb on + strand at 2589.910 kb on + strand at 2589.922 kb on + strand at 2589.956 kb on + strand at 2589.956 kb on + strand at 2589.964 kb on + strand at 2589.966 kb on + strand at 2589.972 kb on - strand at 2589.972 kb on - strand at 2589.972 kb on - strand at 2589.974 kb on - strand at 2589.979 kb on - strand at 2589.989 kb on + strand at 2590.005 kb on - strand at 2590.039 kb on - strand, within BWI76_RS12400 at 2590.039 kb on - strand, within BWI76_RS12400 at 2590.044 kb on - strand, within BWI76_RS12400 at 2590.085 kb on - strand, within BWI76_RS12400 at 2590.086 kb on - strand, within BWI76_RS12400 at 2590.201 kb on - strand, within BWI76_RS12400 at 2590.238 kb on - strand, within BWI76_RS12400 at 2590.340 kb on - strand, within BWI76_RS12400 at 2590.353 kb on - strand, within BWI76_RS12400 at 2590.362 kb on - strand at 2590.407 kb on - strand, within BWI76_RS12400 at 2590.524 kb on + strand, within BWI76_RS12400 at 2590.532 kb on - strand, within BWI76_RS12400 at 2590.532 kb on - strand, within BWI76_RS12400 at 2590.532 kb on - strand, within BWI76_RS12400 at 2590.532 kb on - strand, within BWI76_RS12400 at 2590.532 kb on - strand, within BWI76_RS12400 at 2590.613 kb on + strand at 2590.621 kb on - strand at 2590.621 kb on - strand at 2590.679 kb on - strand at 2590.743 kb on + strand at 2590.751 kb on - strand at 2590.751 kb on - strand at 2590.751 kb on - strand at 2590.751 kb on - strand at 2590.757 kb on + strand at 2590.765 kb on - strand at 2590.775 kb on - strand at 2590.775 kb on - strand at 2590.775 kb on - strand at 2590.775 kb on - strand at 2590.779 kb on - strand at 2590.781 kb on - strand at 2590.791 kb on - strand at 2590.801 kb on + strand at 2590.814 kb on + strand at 2590.822 kb on - strand at 2590.822 kb on - strand at 2590.822 kb on - strand at 2590.822 kb on - strand at 2590.822 kb on - strand at 2590.824 kb on + strand at 2590.835 kb on + strand at 2590.859 kb on + strand at 2590.931 kb on + strand at 2590.939 kb on + strand at 2590.939 kb on + strand at 2590.940 kb on - strand at 2590.940 kb on - strand at 2590.948 kb on + strand at 2590.956 kb on - strand at 2590.961 kb on - strand at 2590.977 kb on + strand at 2591.012 kb on + strand at 2591.015 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.023 kb on + strand at 2591.031 kb on - strand at 2591.031 kb on - strand at 2591.031 kb on - strand at 2591.031 kb on - strand at 2591.031 kb on - strand at 2591.031 kb on - strand at 2591.031 kb on - strand at 2591.037 kb on + strand at 2591.037 kb on + strand at 2591.037 kb on + strand at 2591.044 kb on - strand at 2591.079 kb on + strand at 2591.159 kb on - strand at 2591.179 kb on - strand at 2591.216 kb on - strand at 2591.229 kb on - strand at 2591.235 kb on - strand at 2591.277 kb on + strand, within BWI76_RS12405 at 2591.285 kb on - strand, within BWI76_RS12405 at 2591.312 kb on - strand at 2591.400 kb on + strand, within BWI76_RS12405 at 2591.400 kb on + strand, within BWI76_RS12405 at 2591.400 kb on + strand, within BWI76_RS12405 at 2591.400 kb on + strand, within BWI76_RS12405
Per-strain Table
Position Strand Gene LocusTag Fraction KLEB15 MOI 10 remove 2,588,994 - -0.7 2,589,188 - BWI76_RS12395 0.27 +0.3 2,589,353 + BWI76_RS12395 0.44 -0.1 2,589,381 - BWI76_RS12395 0.47 -0.5 2,589,495 + BWI76_RS12395 0.59 -0.3 2,589,581 + BWI76_RS12395 0.67 +1.3 2,589,605 + BWI76_RS12395 0.70 -0.3 2,589,660 + BWI76_RS12395 0.75 -0.5 2,589,660 + BWI76_RS12395 0.75 +0.9 2,589,660 + BWI76_RS12395 0.75 +1.1 2,589,661 - BWI76_RS12395 0.76 +0.5 2,589,668 - BWI76_RS12395 0.76 -0.3 2,589,678 - BWI76_RS12395 0.77 -0.9 2,589,687 + BWI76_RS12395 0.78 +0.7 2,589,702 + BWI76_RS12395 0.80 -0.6 2,589,708 + BWI76_RS12395 0.80 -0.2 2,589,718 + BWI76_RS12395 0.81 -0.2 2,589,750 + BWI76_RS12395 0.85 -0.2 2,589,781 - BWI76_RS12395 0.88 +0.3 2,589,789 + BWI76_RS12395 0.89 -2.3 2,589,790 + BWI76_RS12395 0.89 -0.0 2,589,797 - BWI76_RS12395 0.89 -0.7 2,589,805 + +0.6 2,589,807 - -1.1 2,589,810 + -0.4 2,589,813 + -0.3 2,589,813 - +0.0 2,589,815 + -0.1 2,589,815 - -1.9 2,589,822 - +1.0 2,589,834 + -1.3 2,589,854 + +0.2 2,589,910 + -1.4 2,589,910 + +0.2 2,589,922 + +0.6 2,589,956 + -0.2 2,589,956 + -0.5 2,589,964 + +5.0 2,589,966 + +0.8 2,589,972 - +0.3 2,589,972 - -0.8 2,589,972 - +0.5 2,589,974 - +0.9 2,589,979 - +0.4 2,589,989 + -1.9 2,590,005 - +0.1 2,590,039 - BWI76_RS12400 0.12 -0.9 2,590,039 - BWI76_RS12400 0.12 +0.1 2,590,044 - BWI76_RS12400 0.13 -1.1 2,590,085 - BWI76_RS12400 0.19 -1.9 2,590,086 - BWI76_RS12400 0.19 -1.9 2,590,201 - BWI76_RS12400 0.37 -3.7 2,590,238 - BWI76_RS12400 0.42 +1.6 2,590,340 - BWI76_RS12400 0.58 +2.1 2,590,353 - BWI76_RS12400 0.60 -3.0 2,590,362 - +1.3 2,590,407 - BWI76_RS12400 0.68 -2.4 2,590,524 + BWI76_RS12400 0.86 +0.8 2,590,532 - BWI76_RS12400 0.87 +2.7 2,590,532 - BWI76_RS12400 0.87 -2.1 2,590,532 - BWI76_RS12400 0.87 -2.8 2,590,532 - BWI76_RS12400 0.87 -0.7 2,590,532 - BWI76_RS12400 0.87 +1.3 2,590,613 + -2.9 2,590,621 - +1.3 2,590,621 - +0.3 2,590,679 - +0.8 2,590,743 + +2.3 2,590,751 - -0.6 2,590,751 - -0.3 2,590,751 - -0.7 2,590,751 - -0.1 2,590,757 + -2.2 2,590,765 - -1.8 2,590,775 - -1.1 2,590,775 - +1.5 2,590,775 - +0.1 2,590,775 - -0.1 2,590,779 - +1.3 2,590,781 - +2.3 2,590,791 - -0.3 2,590,801 + -2.1 2,590,814 + +0.1 2,590,822 - +0.3 2,590,822 - +0.8 2,590,822 - +0.1 2,590,822 - +3.3 2,590,822 - -3.1 2,590,824 + -1.7 2,590,835 + -0.6 2,590,859 + +0.7 2,590,931 + +0.3 2,590,939 + -0.3 2,590,939 + -1.7 2,590,940 - -0.7 2,590,940 - +1.3 2,590,948 + +1.6 2,590,956 - +1.8 2,590,961 - +0.7 2,590,977 + +0.3 2,591,012 + +0.4 2,591,015 + -0.2 2,591,023 + -3.8 2,591,023 + -0.3 2,591,023 + -0.2 2,591,023 + +0.8 2,591,023 + +0.3 2,591,023 + +0.4 2,591,023 + +0.1 2,591,023 + +0.5 2,591,023 + +1.0 2,591,023 + +1.2 2,591,023 + -0.4 2,591,023 + +1.3 2,591,023 + +0.7 2,591,031 - +1.3 2,591,031 - -0.7 2,591,031 - +1.3 2,591,031 - -0.3 2,591,031 - +2.6 2,591,031 - -0.7 2,591,031 - +1.3 2,591,037 + -0.0 2,591,037 + +1.5 2,591,037 + -1.2 2,591,044 - -1.9 2,591,079 + +1.3 2,591,159 - -0.3 2,591,179 - +1.3 2,591,216 - -1.0 2,591,229 - +0.3 2,591,235 - +0.1 2,591,277 + BWI76_RS12405 0.13 +2.3 2,591,285 - BWI76_RS12405 0.13 +0.8 2,591,312 - +1.3 2,591,400 + BWI76_RS12405 0.23 +1.7 2,591,400 + BWI76_RS12405 0.23 +0.4 2,591,400 + BWI76_RS12405 0.23 -0.2 2,591,400 + BWI76_RS12405 0.23 +0.3
Or see this region's nucleotide sequence