Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3557c

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3556c and Rv3557c are separated by 64 nucleotidesRv3557c and Rv3558 are separated by 348 nucleotides Rv3556c: Rv3556c - Probable acetyl-CoA acetyltransferase FadA6 (acetoacetyl-CoA thiolase), at 3,995,804 to 3,996,964 Rv3556c Rv3557c: Rv3557c - Transcriptional regulatory protein (probably TetR-family), at 3,997,029 to 3,997,631 Rv3557c Rv3558: Rv3558 - PPE family protein PPE64, at 3,997,980 to 3,999,638 Rv3558 Position (kb) 3997 3998Strain fitness (log2 ratio) -2 -1 0 1 2at 3996.516 kb on + strand, within Rv3556cat 3996.517 kb on - strand, within Rv3556cat 3996.951 kb on + strandat 3996.951 kb on + strandat 3996.952 kb on - strandat 3997.073 kb on - strandat 3997.159 kb on + strand, within Rv3557cat 3997.192 kb on + strand, within Rv3557cat 3997.192 kb on + strand, within Rv3557cat 3997.310 kb on - strand, within Rv3557cat 3997.489 kb on + strand, within Rv3557cat 3997.489 kb on + strand, within Rv3557cat 3997.643 kb on - strandat 3997.737 kb on + strandat 3997.737 kb on + strandat 3997.738 kb on - strandat 3997.738 kb on - strandat 3997.738 kb on - strandat 3997.738 kb on - strandat 3997.813 kb on + strandat 3997.814 kb on - strandat 3997.908 kb on - strandat 3997.908 kb on - strandat 3997.912 kb on + strandat 3998.029 kb on - strandat 3998.197 kb on - strand, within Rv3558at 3998.400 kb on + strand, within Rv3558at 3998.409 kb on + strand, within Rv3558at 3998.410 kb on - strand, within Rv3558at 3998.442 kb on + strand, within Rv3558

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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3,996,516 + Rv3556c 0.61 -1.2
3,996,517 - Rv3556c 0.61 -0.4
3,996,951 + +0.8
3,996,951 + +0.2
3,996,952 - -0.2
3,997,073 - +0.7
3,997,159 + Rv3557c 0.22 -0.5
3,997,192 + Rv3557c 0.27 -1.5
3,997,192 + Rv3557c 0.27 -1.0
3,997,310 - Rv3557c 0.47 -0.3
3,997,489 + Rv3557c 0.76 -0.9
3,997,489 + Rv3557c 0.76 -0.7
3,997,643 - +0.2
3,997,737 + -2.0
3,997,737 + -0.4
3,997,738 - -1.2
3,997,738 - +0.5
3,997,738 - -0.1
3,997,738 - +0.2
3,997,813 + -1.2
3,997,814 - -1.4
3,997,908 - +0.2
3,997,908 - -0.6
3,997,912 + +1.9
3,998,029 - -0.3
3,998,197 - Rv3558 0.13 -0.2
3,998,400 + Rv3558 0.25 -0.1
3,998,409 + Rv3558 0.26 -0.8
3,998,410 - Rv3558 0.26 -0.4
3,998,442 + Rv3558 0.28 -0.2

Or see this region's nucleotide sequence