Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2970A

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2970c and Rv2970A are separated by 230 nucleotidesRv2970A and Rv2971 overlap by 4 nucleotidesRv2971 and Rv2972c are separated by 73 nucleotides Rv2970c: Rv2970c - Probable lipase/esterase LipN, at 3,324,573 to 3,325,703 Rv2970c Rv2970A: Rv2970A - Conserved hypothetical protein, at 3,325,934 to 3,326,104 Rv2970A Rv2971: Rv2971 - Probable oxidoreductase, at 3,326,101 to 3,326,949 Rv2971 Rv2972c: Rv2972c - Possible conserved membrane or exported protein, at 3,327,023 to 3,327,736 Rv2972c Position (kb) 3325 3326 3327Strain fitness (log2 ratio) -1 0 1at 3325.001 kb on - strand, within Rv2970cat 3325.125 kb on + strand, within Rv2970cat 3325.138 kb on + strand, within Rv2970cat 3325.139 kb on - strand, within Rv2970cat 3325.139 kb on - strand, within Rv2970cat 3325.139 kb on - strand, within Rv2970cat 3325.200 kb on + strand, within Rv2970cat 3325.200 kb on + strand, within Rv2970cat 3325.286 kb on - strand, within Rv2970cat 3325.328 kb on - strand, within Rv2970cat 3325.417 kb on - strand, within Rv2970cat 3325.809 kb on - strandat 3325.809 kb on - strandat 3325.845 kb on + strandat 3325.892 kb on + strandat 3325.951 kb on + strand, within Rv2970Aat 3326.950 kb on + strandat 3327.025 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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3,325,001 - Rv2970c 0.38 -0.4
3,325,125 + Rv2970c 0.49 -1.0
3,325,138 + Rv2970c 0.50 -1.0
3,325,139 - Rv2970c 0.50 -1.0
3,325,139 - Rv2970c 0.50 -1.7
3,325,139 - Rv2970c 0.50 +0.5
3,325,200 + Rv2970c 0.55 -0.0
3,325,200 + Rv2970c 0.55 -0.2
3,325,286 - Rv2970c 0.63 -0.5
3,325,328 - Rv2970c 0.67 -0.0
3,325,417 - Rv2970c 0.75 -0.3
3,325,809 - -0.2
3,325,809 - -0.5
3,325,845 + -0.2
3,325,892 + -0.6
3,325,951 + Rv2970A 0.10 -0.5
3,326,950 + +0.2
3,327,025 - +0.2

Or see this region's nucleotide sequence