Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1958c

Experiment: L-Valine 10 mM (N)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1955 and Rv1956 are separated by 41 nucleotidesRv1956 and Rv1957 overlap by 4 nucleotidesRv1957 and Rv1958c overlap by 112 nucleotidesRv1958c and Rv1959c are separated by 48 nucleotidesRv1959c and Rv1960c overlap by 4 nucleotidesRv1960c and Rv1961 overlap by 14 nucleotides Rv1955: Rv1955 - Possible toxin HigB, at 2,201,719 to 2,202,096 Rv1955 Rv1956: Rv1956 - Possible antitoxin HigA, at 2,202,138 to 2,202,587 Rv1956 Rv1957: Rv1957 - Hypothetical protein, at 2,202,584 to 2,203,129 Rv1957 Rv1958c: Rv1958c - Hypothetical protein, at 2,203,018 to 2,203,632 Rv1958c Rv1959c: Rv1959c - Possible toxin ParE1, at 2,203,681 to 2,203,977 Rv1959c Rv1960c: Rv1960c - Possible antitoxin ParD1, at 2,203,974 to 2,204,225 Rv1960c Rv1961: Rv1961 - Hypothetical protein, at 2,204,212 to 2,204,706 Rv1961 Position (kb) 2203 2204Strain fitness (log2 ratio) -2 -1 0 1 2 3at 2202.115 kb on + strandat 2202.115 kb on + strandat 2202.123 kb on + strandat 2202.314 kb on + strand, within Rv1956at 2202.377 kb on + strand, within Rv1956at 2202.377 kb on + strand, within Rv1956at 2202.377 kb on + strand, within Rv1956at 2202.390 kb on + strand, within Rv1956at 2202.390 kb on + strand, within Rv1956at 2202.455 kb on + strand, within Rv1956at 2202.455 kb on + strand, within Rv1956at 2202.456 kb on - strand, within Rv1956at 2202.729 kb on - strand, within Rv1957at 2202.729 kb on - strand, within Rv1957at 2202.773 kb on - strand, within Rv1957at 2203.065 kb on + strandat 2203.065 kb on + strandat 2203.065 kb on + strandat 2203.066 kb on - strandat 2203.178 kb on - strand, within Rv1958cat 2203.178 kb on - strand, within Rv1958cat 2203.438 kb on - strand, within Rv1958cat 2203.529 kb on - strand, within Rv1958cat 2203.546 kb on + strand, within Rv1958cat 2203.546 kb on + strand, within Rv1958cat 2203.546 kb on + strand, within Rv1958cat 2203.546 kb on + strand, within Rv1958cat 2203.547 kb on - strand, within Rv1958cat 2203.547 kb on - strand, within Rv1958cat 2203.547 kb on - strand, within Rv1958cat 2203.547 kb on - strand, within Rv1958cat 2203.877 kb on + strand, within Rv1959cat 2203.877 kb on + strand, within Rv1959cat 2203.877 kb on + strand, within Rv1959cat 2203.878 kb on - strand, within Rv1959cat 2203.910 kb on + strand, within Rv1959cat 2203.910 kb on + strand, within Rv1959cat 2203.911 kb on - strand, within Rv1959cat 2203.911 kb on - strand, within Rv1959cat 2203.964 kb on + strandat 2203.964 kb on + strandat 2204.003 kb on + strand, within Rv1960cat 2204.003 kb on + strand, within Rv1960cat 2204.188 kb on + strand, within Rv1960cat 2204.188 kb on + strand, within Rv1960cat 2204.219 kb on + strandat 2204.249 kb on + strandat 2204.259 kb on + strandat 2204.389 kb on + strand, within Rv1961at 2204.390 kb on - strand, within Rv1961at 2204.401 kb on + strand, within Rv1961at 2204.402 kb on - strand, within Rv1961at 2204.402 kb on - strand, within Rv1961at 2204.402 kb on - strand, within Rv1961

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
remove
2,202,115 + -1.9
2,202,115 + -0.4
2,202,123 + -0.9
2,202,314 + Rv1956 0.39 -0.3
2,202,377 + Rv1956 0.53 +0.1
2,202,377 + Rv1956 0.53 -0.4
2,202,377 + Rv1956 0.53 -0.7
2,202,390 + Rv1956 0.56 +0.4
2,202,390 + Rv1956 0.56 -0.2
2,202,455 + Rv1956 0.70 +1.3
2,202,455 + Rv1956 0.70 -1.1
2,202,456 - Rv1956 0.71 -0.6
2,202,729 - Rv1957 0.27 +1.0
2,202,729 - Rv1957 0.27 +1.1
2,202,773 - Rv1957 0.35 -0.3
2,203,065 + +1.3
2,203,065 + -0.8
2,203,065 + +0.2
2,203,066 - -0.3
2,203,178 - Rv1958c 0.26 -0.5
2,203,178 - Rv1958c 0.26 +0.6
2,203,438 - Rv1958c 0.68 +0.1
2,203,529 - Rv1958c 0.83 +0.4
2,203,546 + Rv1958c 0.86 -0.6
2,203,546 + Rv1958c 0.86 -1.1
2,203,546 + Rv1958c 0.86 -0.5
2,203,546 + Rv1958c 0.86 +0.1
2,203,547 - Rv1958c 0.86 -0.1
2,203,547 - Rv1958c 0.86 -0.0
2,203,547 - Rv1958c 0.86 +1.0
2,203,547 - Rv1958c 0.86 +1.1
2,203,877 + Rv1959c 0.66 +1.3
2,203,877 + Rv1959c 0.66 +0.2
2,203,877 + Rv1959c 0.66 +0.3
2,203,878 - Rv1959c 0.66 -0.5
2,203,910 + Rv1959c 0.77 +0.5
2,203,910 + Rv1959c 0.77 -0.4
2,203,911 - Rv1959c 0.77 -0.8
2,203,911 - Rv1959c 0.77 -0.2
2,203,964 + -0.7
2,203,964 + -0.3
2,204,003 + Rv1960c 0.12 +0.1
2,204,003 + Rv1960c 0.12 -0.4
2,204,188 + Rv1960c 0.85 -0.1
2,204,188 + Rv1960c 0.85 -0.1
2,204,219 + +0.5
2,204,249 + -0.6
2,204,259 + -0.5
2,204,389 + Rv1961 0.36 -0.1
2,204,390 - Rv1961 0.36 -0.3
2,204,401 + Rv1961 0.38 -0.2
2,204,402 - Rv1961 0.38 +3.3
2,204,402 - Rv1961 0.38 -0.1
2,204,402 - Rv1961 0.38 -0.4

Or see this region's nucleotide sequence