Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1172c

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1170 and Rv1171 are separated by 91 nucleotidesRv1171 and Rv1172c are separated by 7 nucleotidesRv1172c and Rv1173 are separated by 249 nucleotides Rv1170: Rv1170 - N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase), at 1,300,304 to 1,301,215 Rv1170 Rv1171: Rv1171 - Conserved hypothetical protein, at 1,301,307 to 1,301,747 Rv1171 Rv1172c: Rv1172c - PE family protein PE12, at 1,301,755 to 1,302,681 Rv1172c Rv1173: Rv1173 - Probable F420 biosynthesis protein FbiC, at 1,302,931 to 1,305,501 Rv1173 Position (kb) 1301 1302 1303Strain fitness (log2 ratio) -2 -1 0 1 2at 1301.120 kb on + strand, within Rv1170at 1301.121 kb on - strand, within Rv1170at 1301.121 kb on - strand, within Rv1170at 1301.213 kb on + strandat 1301.214 kb on - strandat 1301.457 kb on + strand, within Rv1171at 1301.458 kb on - strand, within Rv1171at 1301.458 kb on - strand, within Rv1171at 1301.458 kb on - strand, within Rv1171at 1301.458 kb on - strand, within Rv1171at 1301.459 kb on + strand, within Rv1171at 1301.585 kb on - strand, within Rv1171at 1301.659 kb on - strand, within Rv1171at 1301.874 kb on + strand, within Rv1172cat 1301.966 kb on + strand, within Rv1172cat 1301.967 kb on - strand, within Rv1172cat 1301.967 kb on - strand, within Rv1172cat 1301.992 kb on + strand, within Rv1172cat 1301.993 kb on - strand, within Rv1172cat 1302.002 kb on + strand, within Rv1172cat 1302.003 kb on - strand, within Rv1172cat 1302.072 kb on - strand, within Rv1172cat 1302.279 kb on - strand, within Rv1172cat 1302.334 kb on - strand, within Rv1172cat 1302.419 kb on + strand, within Rv1172cat 1302.419 kb on + strand, within Rv1172cat 1302.420 kb on - strand, within Rv1172cat 1302.497 kb on + strand, within Rv1172cat 1302.497 kb on + strand, within Rv1172cat 1302.686 kb on + strandat 1302.842 kb on + strandat 1302.854 kb on + strandat 1302.903 kb on + strandat 1302.922 kb on + strandat 1302.981 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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1,301,120 + Rv1170 0.89 +0.1
1,301,121 - Rv1170 0.90 +1.8
1,301,121 - Rv1170 0.90 -1.1
1,301,213 + +0.8
1,301,214 - -0.4
1,301,457 + Rv1171 0.34 +1.8
1,301,458 - Rv1171 0.34 +0.0
1,301,458 - Rv1171 0.34 -1.8
1,301,458 - Rv1171 0.34 -0.3
1,301,458 - Rv1171 0.34 +0.0
1,301,459 + Rv1171 0.34 -0.6
1,301,585 - Rv1171 0.63 +0.5
1,301,659 - Rv1171 0.80 -1.7
1,301,874 + Rv1172c 0.13 -0.2
1,301,966 + Rv1172c 0.23 -0.5
1,301,967 - Rv1172c 0.23 +0.1
1,301,967 - Rv1172c 0.23 +0.4
1,301,992 + Rv1172c 0.26 +0.8
1,301,993 - Rv1172c 0.26 -0.1
1,302,002 + Rv1172c 0.27 +0.8
1,302,003 - Rv1172c 0.27 -0.7
1,302,072 - Rv1172c 0.34 -0.0
1,302,279 - Rv1172c 0.57 +0.9
1,302,334 - Rv1172c 0.62 -0.3
1,302,419 + Rv1172c 0.72 -0.6
1,302,419 + Rv1172c 0.72 -0.3
1,302,420 - Rv1172c 0.72 -0.4
1,302,497 + Rv1172c 0.80 +0.6
1,302,497 + Rv1172c 0.80 +0.4
1,302,686 + -0.2
1,302,842 + -0.3
1,302,854 + +0.3
1,302,903 + +0.4
1,302,922 + +0.1
1,302,981 - +0.1

Or see this region's nucleotide sequence