Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3547

Experiment: L-Valine 10 mM (N)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3546 and Rv3547 are separated by 111 nucleotidesRv3547 and Rv3548c are separated by 82 nucleotides Rv3546: Rv3546 - Probable acetyl-CoA acetyltransferase FadA5 (acetoacetyl-CoA thiolase), at 3,985,557 to 3,986,732 Rv3546 Rv3547: Rv3547 - Deazaflavin-dependent nitroreductase Ddn, at 3,986,844 to 3,987,299 Rv3547 Rv3548c: Rv3548c - Probable short-chain type dehydrogenase/reductase, at 3,987,382 to 3,988,296 Rv3548c Position (kb) 3986 3987 3988Strain fitness (log2 ratio) -1 0 1 2at 3986.412 kb on + strand, within Rv3546at 3986.412 kb on + strand, within Rv3546at 3986.413 kb on - strand, within Rv3546at 3986.730 kb on + strandat 3986.735 kb on + strandat 3986.735 kb on + strandat 3986.736 kb on - strandat 3986.788 kb on + strandat 3986.792 kb on + strandat 3986.793 kb on - strandat 3986.832 kb on - strandat 3986.918 kb on + strand, within Rv3547at 3986.918 kb on + strand, within Rv3547at 3986.919 kb on - strand, within Rv3547at 3986.929 kb on - strand, within Rv3547at 3987.037 kb on - strand, within Rv3547at 3987.037 kb on - strand, within Rv3547at 3987.109 kb on - strand, within Rv3547at 3987.142 kb on + strand, within Rv3547at 3987.231 kb on + strand, within Rv3547at 3987.232 kb on - strand, within Rv3547at 3987.249 kb on + strand, within Rv3547at 3987.249 kb on + strand, within Rv3547at 3987.250 kb on - strand, within Rv3547at 3987.380 kb on - strandat 3987.383 kb on + strandat 3987.392 kb on + strandat 3987.393 kb on - strandat 3987.539 kb on - strand, within Rv3548cat 3987.580 kb on + strand, within Rv3548cat 3987.581 kb on - strand, within Rv3548cat 3987.776 kb on + strand, within Rv3548cat 3987.777 kb on - strand, within Rv3548cat 3987.802 kb on + strand, within Rv3548cat 3987.803 kb on - strand, within Rv3548cat 3987.803 kb on - strand, within Rv3548cat 3987.803 kb on - strand, within Rv3548cat 3987.803 kb on - strand, within Rv3548cat 3988.026 kb on - strand, within Rv3548cat 3988.026 kb on - strand, within Rv3548c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
remove
3,986,412 + Rv3546 0.73 -0.7
3,986,412 + Rv3546 0.73 -0.3
3,986,413 - Rv3546 0.73 -0.5
3,986,730 + -0.3
3,986,735 + -0.4
3,986,735 + +0.5
3,986,736 - -0.3
3,986,788 + +0.4
3,986,792 + -0.2
3,986,793 - -0.7
3,986,832 - -0.8
3,986,918 + Rv3547 0.16 -0.4
3,986,918 + Rv3547 0.16 -0.1
3,986,919 - Rv3547 0.16 +1.0
3,986,929 - Rv3547 0.19 -0.5
3,987,037 - Rv3547 0.42 +0.4
3,987,037 - Rv3547 0.42 +1.9
3,987,109 - Rv3547 0.58 +0.1
3,987,142 + Rv3547 0.65 -0.1
3,987,231 + Rv3547 0.85 +1.4
3,987,232 - Rv3547 0.85 -0.1
3,987,249 + Rv3547 0.89 -0.6
3,987,249 + Rv3547 0.89 +0.3
3,987,250 - Rv3547 0.89 +0.2
3,987,380 - +1.8
3,987,383 + +1.8
3,987,392 + -0.8
3,987,393 - -0.5
3,987,539 - Rv3548c 0.17 +0.0
3,987,580 + Rv3548c 0.22 -0.3
3,987,581 - Rv3548c 0.22 -0.3
3,987,776 + Rv3548c 0.43 -0.0
3,987,777 - Rv3548c 0.43 +0.7
3,987,802 + Rv3548c 0.46 +0.4
3,987,803 - Rv3548c 0.46 -0.1
3,987,803 - Rv3548c 0.46 -0.8
3,987,803 - Rv3548c 0.46 -0.3
3,987,803 - Rv3548c 0.46 -1.1
3,988,026 - Rv3548c 0.70 -0.5
3,988,026 - Rv3548c 0.70 -0.4

Or see this region's nucleotide sequence