Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3291c

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3290c and Rv3291c are separated by 50 nucleotidesRv3291c and Rv3292 are separated by 30 nucleotides Rv3290c: Rv3290c - Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase), at 3,670,445 to 3,671,794 Rv3290c Rv3291c: Rv3291c - Probable transcriptional regulatory protein LrpA (Lrp/AsnC-family), at 3,671,845 to 3,672,297 Rv3291c Rv3292: Rv3292 - Conserved hypothetical protein, at 3,672,328 to 3,673,575 Rv3292 Position (kb) 3671 3672 3673Strain fitness (log2 ratio) -1 0 1 2at 3670.883 kb on + strand, within Rv3290cat 3670.883 kb on + strand, within Rv3290cat 3670.939 kb on - strand, within Rv3290cat 3670.976 kb on + strand, within Rv3290cat 3670.977 kb on - strand, within Rv3290cat 3671.156 kb on + strand, within Rv3290cat 3671.196 kb on + strand, within Rv3290cat 3671.196 kb on + strand, within Rv3290cat 3671.197 kb on - strand, within Rv3290cat 3671.197 kb on - strand, within Rv3290cat 3671.276 kb on - strand, within Rv3290cat 3671.276 kb on - strand, within Rv3290cat 3671.276 kb on - strand, within Rv3290cat 3671.276 kb on - strand, within Rv3290cat 3671.499 kb on + strand, within Rv3290cat 3671.587 kb on + strand, within Rv3290cat 3671.587 kb on + strand, within Rv3290cat 3671.588 kb on - strand, within Rv3290cat 3671.588 kb on - strand, within Rv3290cat 3671.628 kb on + strand, within Rv3290cat 3671.643 kb on - strand, within Rv3290cat 3671.644 kb on + strand, within Rv3290cat 3671.645 kb on - strand, within Rv3290cat 3671.659 kb on - strand, within Rv3290cat 3671.659 kb on - strand, within Rv3290cat 3671.690 kb on + strandat 3671.690 kb on + strandat 3671.690 kb on + strandat 3671.690 kb on + strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.758 kb on + strandat 3671.981 kb on + strand, within Rv3291cat 3671.981 kb on + strand, within Rv3291cat 3671.982 kb on - strand, within Rv3291cat 3672.028 kb on - strand, within Rv3291cat 3672.137 kb on + strand, within Rv3291cat 3672.397 kb on + strandat 3672.398 kb on - strandat 3672.398 kb on - strandat 3672.438 kb on - strandat 3672.756 kb on - strand, within Rv3292at 3672.969 kb on + strand, within Rv3292at 3673.026 kb on - strand, within Rv3292at 3673.261 kb on + strand, within Rv3292at 3673.261 kb on + strand, within Rv3292

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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3,670,883 + Rv3290c 0.32 +0.3
3,670,883 + Rv3290c 0.32 +0.1
3,670,939 - Rv3290c 0.37 -0.1
3,670,976 + Rv3290c 0.39 +0.2
3,670,977 - Rv3290c 0.39 -1.3
3,671,156 + Rv3290c 0.53 -0.1
3,671,196 + Rv3290c 0.56 -0.6
3,671,196 + Rv3290c 0.56 -0.5
3,671,197 - Rv3290c 0.56 +1.2
3,671,197 - Rv3290c 0.56 +0.2
3,671,276 - Rv3290c 0.62 +0.3
3,671,276 - Rv3290c 0.62 -0.3
3,671,276 - Rv3290c 0.62 -0.4
3,671,276 - Rv3290c 0.62 +0.9
3,671,499 + Rv3290c 0.78 -0.4
3,671,587 + Rv3290c 0.85 +0.9
3,671,587 + Rv3290c 0.85 -0.2
3,671,588 - Rv3290c 0.85 -1.1
3,671,588 - Rv3290c 0.85 -0.4
3,671,628 + Rv3290c 0.88 -1.1
3,671,643 - Rv3290c 0.89 -0.3
3,671,644 + Rv3290c 0.89 -0.6
3,671,645 - Rv3290c 0.89 -0.1
3,671,659 - Rv3290c 0.90 -0.3
3,671,659 - Rv3290c 0.90 -0.3
3,671,690 + -0.1
3,671,690 + -0.4
3,671,690 + +0.3
3,671,690 + +0.9
3,671,691 - -0.4
3,671,691 - -0.7
3,671,691 - -0.4
3,671,691 - -0.8
3,671,691 - +0.3
3,671,691 - +0.8
3,671,758 + -1.2
3,671,981 + Rv3291c 0.30 +0.4
3,671,981 + Rv3291c 0.30 +0.3
3,671,982 - Rv3291c 0.30 +0.4
3,672,028 - Rv3291c 0.40 +0.9
3,672,137 + Rv3291c 0.64 -0.2
3,672,397 + +1.8
3,672,398 - +0.8
3,672,398 - -0.4
3,672,438 - +0.4
3,672,756 - Rv3292 0.34 -1.1
3,672,969 + Rv3292 0.51 +0.1
3,673,026 - Rv3292 0.56 -0.3
3,673,261 + Rv3292 0.75 -1.1
3,673,261 + Rv3292 0.75 -0.7

Or see this region's nucleotide sequence