Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2991

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2990c and Rv2991 are separated by 262 nucleotidesRv2991 and GFF3112 are separated by 73 nucleotidesGFF3112 and GFF3113 are separated by 39 nucleotidesGFF3113 and Rv2992c are separated by 74 nucleotides Rv2990c: Rv2990c - Hypothetical protein, at 3,346,859 to 3,347,719 Rv2990c Rv2991: Rv2991 - Conserved protein, at 3,347,982 to 3,348,473 Rv2991 GFF3112 - tRNA-Glu, at 3,348,547 to 3,348,619 GFF3112 GFF3113 - tRNA-Gln, at 3,348,659 to 3,348,730 GFF3113 Rv2992c: Rv2992c - Glutamyl-tRNA synthetase GltS (glutamate--tRNA ligase) (glutamyl-tRNA synthase) (GLURS), at 3,348,805 to 3,350,277 Rv2992c Position (kb) 3347 3348 3349Strain fitness (log2 ratio) -2 -1 0 1 2at 3347.232 kb on + strand, within Rv2990cat 3347.233 kb on - strand, within Rv2990cat 3347.233 kb on - strand, within Rv2990cat 3347.233 kb on - strand, within Rv2990cat 3347.233 kb on - strand, within Rv2990cat 3347.250 kb on - strand, within Rv2990cat 3347.253 kb on + strand, within Rv2990cat 3347.253 kb on + strand, within Rv2990cat 3347.253 kb on + strand, within Rv2990cat 3347.253 kb on + strand, within Rv2990cat 3347.314 kb on - strand, within Rv2990cat 3347.347 kb on - strand, within Rv2990cat 3347.396 kb on + strand, within Rv2990cat 3347.441 kb on - strand, within Rv2990cat 3347.631 kb on - strand, within Rv2990cat 3347.631 kb on - strand, within Rv2990cat 3347.631 kb on - strand, within Rv2990cat 3347.634 kb on + strandat 3347.634 kb on + strandat 3347.635 kb on - strandat 3347.635 kb on - strandat 3347.657 kb on + strandat 3347.658 kb on - strandat 3347.658 kb on - strandat 3347.658 kb on - strandat 3347.658 kb on - strandat 3347.818 kb on - strandat 3347.886 kb on - strandat 3347.898 kb on - strandat 3347.913 kb on - strandat 3348.111 kb on + strand, within Rv2991at 3348.222 kb on + strand, within Rv2991at 3348.222 kb on + strand, within Rv2991at 3348.222 kb on + strand, within Rv2991at 3348.223 kb on - strand, within Rv2991at 3348.223 kb on - strand, within Rv2991at 3348.331 kb on - strand, within Rv2991at 3348.471 kb on + strandat 3348.471 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.644 kb on - strandat 3348.741 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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3,347,232 + Rv2990c 0.43 +0.8
3,347,233 - Rv2990c 0.43 +0.1
3,347,233 - Rv2990c 0.43 +0.0
3,347,233 - Rv2990c 0.43 -0.4
3,347,233 - Rv2990c 0.43 -0.9
3,347,250 - Rv2990c 0.45 +0.8
3,347,253 + Rv2990c 0.46 -1.2
3,347,253 + Rv2990c 0.46 -0.3
3,347,253 + Rv2990c 0.46 +0.1
3,347,253 + Rv2990c 0.46 -0.5
3,347,314 - Rv2990c 0.53 -1.4
3,347,347 - Rv2990c 0.57 -0.6
3,347,396 + Rv2990c 0.62 -0.5
3,347,441 - Rv2990c 0.68 -0.3
3,347,631 - Rv2990c 0.90 +0.1
3,347,631 - Rv2990c 0.90 -0.4
3,347,631 - Rv2990c 0.90 -0.5
3,347,634 + -0.3
3,347,634 + -0.7
3,347,635 - +0.7
3,347,635 - -0.3
3,347,657 + +0.0
3,347,658 - -1.4
3,347,658 - -0.8
3,347,658 - -1.6
3,347,658 - -0.3
3,347,818 - -1.3
3,347,886 - -1.5
3,347,898 - +0.3
3,347,913 - +1.8
3,348,111 + Rv2991 0.26 -1.1
3,348,222 + Rv2991 0.49 -0.1
3,348,222 + Rv2991 0.49 -1.0
3,348,222 + Rv2991 0.49 +0.8
3,348,223 - Rv2991 0.49 -1.0
3,348,223 - Rv2991 0.49 -0.8
3,348,331 - Rv2991 0.71 -1.9
3,348,471 + +0.1
3,348,471 + +0.1
3,348,643 + +1.0
3,348,643 + -0.8
3,348,643 + +0.4
3,348,643 + -0.0
3,348,643 + -0.6
3,348,643 + -0.0
3,348,644 - +0.1
3,348,741 - -0.4

Or see this region's nucleotide sequence