Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2784c

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2783c and Rv2784c are separated by 353 nucleotidesRv2784c and Rv2785c are separated by 12 nucleotidesRv2785c and Rv2786c are separated by 156 nucleotides Rv2783c: Rv2783c - Bifunctional protein polyribonucleotide nucleotidyltransferase GpsI: guanosine pentaphosphate synthetase + polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) (pnpase), at 3,090,339 to 3,092,597 Rv2783c Rv2784c: Rv2784c - Probable lipoprotein LppU, at 3,092,951 to 3,093,466 Rv2784c Rv2785c: Rv2785c - 30S ribosomal protein S15 RpsO, at 3,093,479 to 3,093,748 Rv2785c Rv2786c: Rv2786c - Probable bifunctional FAD synthetase/riboflavin biosynthesis protein RibF: riboflavin kinase (flavokinase) + FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)(FAD diphosphorylase) (flavin adenine dinucleotide synthetase), at 3,093,905 to 3,094,900 Rv2786c Position (kb) 3092 3093 3094Strain fitness (log2 ratio) -1 0 1 2at 3092.897 kb on - strandat 3093.009 kb on + strand, within Rv2784cat 3093.009 kb on + strand, within Rv2784cat 3093.010 kb on - strand, within Rv2784cat 3093.010 kb on - strand, within Rv2784cat 3093.010 kb on - strand, within Rv2784cat 3093.010 kb on - strand, within Rv2784cat 3093.015 kb on + strand, within Rv2784cat 3093.015 kb on + strand, within Rv2784cat 3093.016 kb on - strand, within Rv2784cat 3093.146 kb on - strand, within Rv2784cat 3093.160 kb on + strand, within Rv2784cat 3093.160 kb on + strand, within Rv2784cat 3093.161 kb on - strand, within Rv2784cat 3093.235 kb on - strand, within Rv2784cat 3093.838 kb on - strandat 3093.838 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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3,092,897 - +1.8
3,093,009 + Rv2784c 0.11 -0.4
3,093,009 + Rv2784c 0.11 -0.2
3,093,010 - Rv2784c 0.11 -0.6
3,093,010 - Rv2784c 0.11 -0.2
3,093,010 - Rv2784c 0.11 -1.0
3,093,010 - Rv2784c 0.11 -1.2
3,093,015 + Rv2784c 0.12 +0.2
3,093,015 + Rv2784c 0.12 -1.0
3,093,016 - Rv2784c 0.13 -1.4
3,093,146 - Rv2784c 0.38 +0.5
3,093,160 + Rv2784c 0.41 -0.6
3,093,160 + Rv2784c 0.41 +0.2
3,093,161 - Rv2784c 0.41 +0.7
3,093,235 - Rv2784c 0.55 -0.7
3,093,838 - +0.1
3,093,838 - +1.8

Or see this region's nucleotide sequence