Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2605c

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2603c and Rv2604c are separated by 132 nucleotidesRv2604c and Rv2605c are separated by 7 nucleotidesRv2605c and Rv2606c are separated by 28 nucleotides Rv2603c: Rv2603c - Highly conserved protein, at 2,930,805 to 2,931,560 Rv2603c Rv2604c: Rv2604c - Probable glutamine amidotransferase SnoP, at 2,931,693 to 2,932,289 Rv2604c Rv2605c: Rv2605c - Probable acyl-CoA thioesterase II TesB2 (TEII), at 2,932,297 to 2,933,142 Rv2605c Rv2606c: Rv2606c - Possible pyridoxine biosynthesis protein SnzP, at 2,933,171 to 2,934,070 Rv2606c Position (kb) 2932 2933 2934Strain fitness (log2 ratio) -1 0 1 2at 2931.604 kb on + strandat 2931.604 kb on + strandat 2931.604 kb on + strandat 2931.604 kb on + strandat 2931.605 kb on - strandat 2931.605 kb on - strandat 2931.895 kb on - strand, within Rv2604cat 2932.440 kb on - strand, within Rv2605cat 2932.440 kb on - strand, within Rv2605cat 2932.789 kb on - strand, within Rv2605cat 2932.846 kb on + strand, within Rv2605cat 2932.985 kb on + strand, within Rv2605cat 2932.985 kb on + strand, within Rv2605cat 2933.032 kb on + strand, within Rv2605cat 2933.033 kb on - strand, within Rv2605cat 2933.460 kb on - strand, within Rv2606cat 2933.757 kb on + strand, within Rv2606cat 2933.758 kb on - strand, within Rv2606cat 2933.758 kb on - strand, within Rv2606cat 2933.758 kb on - strand, within Rv2606cat 2933.815 kb on + strand, within Rv2606cat 2933.816 kb on - strand, within Rv2606cat 2934.055 kb on + strandat 2934.092 kb on + strandat 2934.093 kb on - strandat 2934.093 kb on - strandat 2934.097 kb on + strandat 2934.097 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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2,931,604 + -1.5
2,931,604 + +0.9
2,931,604 + -0.6
2,931,604 + +0.6
2,931,605 - -0.6
2,931,605 - +0.1
2,931,895 - Rv2604c 0.34 +0.8
2,932,440 - Rv2605c 0.17 -0.6
2,932,440 - Rv2605c 0.17 -0.9
2,932,789 - Rv2605c 0.58 -0.0
2,932,846 + Rv2605c 0.65 -1.0
2,932,985 + Rv2605c 0.81 -0.1
2,932,985 + Rv2605c 0.81 -0.4
2,933,032 + Rv2605c 0.87 -1.2
2,933,033 - Rv2605c 0.87 +0.1
2,933,460 - Rv2606c 0.32 +1.8
2,933,757 + Rv2606c 0.65 -0.5
2,933,758 - Rv2606c 0.65 -0.1
2,933,758 - Rv2606c 0.65 -0.8
2,933,758 - Rv2606c 0.65 +0.3
2,933,815 + Rv2606c 0.72 -1.1
2,933,816 - Rv2606c 0.72 -0.4
2,934,055 + +0.2
2,934,092 + +1.3
2,934,093 - +0.3
2,934,093 - +0.2
2,934,097 + -0.0
2,934,097 + -0.1

Or see this region's nucleotide sequence