Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2436

Experiment: L-Valine 10 mM (N)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2435c and Rv2436 are separated by 480 nucleotidesRv2436 and Rv2437 are separated by 231 nucleotidesRv2437 and Rv2438c overlap by 4 nucleotides Rv2435c: Rv2435c - Probable cyclase (adenylyl-or guanylyl-)(adenylate-or guanylate-), at 2,730,557 to 2,732,749 Rv2435c Rv2436: Rv2436 - Ribokinase RbsK, at 2,733,230 to 2,734,144 Rv2436 Rv2437: Rv2437 - Conserved transmembrane protein, at 2,734,376 to 2,734,795 Rv2437 Rv2438c: Rv2438c - Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]), at 2,734,792 to 2,736,831 Rv2438c Position (kb) 2733 2734 2735Strain fitness (log2 ratio) -1 0 1at 2732.235 kb on + strand, within Rv2435cat 2732.236 kb on - strand, within Rv2435cat 2732.251 kb on - strand, within Rv2435cat 2732.343 kb on + strand, within Rv2435cat 2732.571 kb on + strandat 2732.605 kb on + strandat 2732.683 kb on + strandat 2732.811 kb on + strandat 2732.931 kb on + strandat 2732.974 kb on + strandat 2732.974 kb on + strandat 2732.975 kb on - strandat 2732.975 kb on - strandat 2733.251 kb on - strandat 2733.251 kb on - strandat 2733.957 kb on + strand, within Rv2436at 2734.201 kb on - strandat 2734.746 kb on - strand, within Rv2437at 2734.794 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
remove
2,732,235 + Rv2435c 0.77 -0.0
2,732,236 - Rv2435c 0.77 +0.2
2,732,251 - Rv2435c 0.77 -0.8
2,732,343 + Rv2435c 0.81 +1.7
2,732,571 + -0.3
2,732,605 + +0.1
2,732,683 + -0.1
2,732,811 + +1.4
2,732,931 + -0.5
2,732,974 + -0.2
2,732,974 + +0.7
2,732,975 - -1.0
2,732,975 - +0.2
2,733,251 - +0.4
2,733,251 - -0.3
2,733,957 + Rv2436 0.79 -0.8
2,734,201 - -0.2
2,734,746 - Rv2437 0.88 -0.4
2,734,794 - -0.3

Or see this region's nucleotide sequence