Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0959

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0958 and Rv0959 overlap by 8 nucleotidesRv0959 and Rv0959A are separated by 53 nucleotidesRv0959A and Rv0960 overlap by 4 nucleotidesRv0960 and Rv0961 are separated by 145 nucleotides Rv0958: Rv0958 - Possible magnesium chelatase, at 1,069,883 to 1,071,262 Rv0958 Rv0959: Rv0959 - Conserved hypothetical protein, at 1,071,255 to 1,073,273 Rv0959 Rv0959A: Rv0959A - Possible antitoxin VapB9, at 1,073,327 to 1,073,548 Rv0959A Rv0960: Rv0960 - Possible toxin VapC9, at 1,073,545 to 1,073,928 Rv0960 Rv0961: Rv0961 - Probable integral membrane protein, at 1,074,074 to 1,074,421 Rv0961 Position (kb) 1071 1072 1073 1074Strain fitness (log2 ratio) -2 -1 0 1 2at 1070.279 kb on + strand, within Rv0958at 1070.570 kb on + strand, within Rv0958at 1070.570 kb on + strand, within Rv0958at 1070.708 kb on + strand, within Rv0958at 1071.205 kb on - strandat 1071.206 kb on + strandat 1071.207 kb on - strandat 1071.260 kb on + strandat 1071.328 kb on + strandat 1071.328 kb on + strandat 1071.329 kb on - strandat 1071.333 kb on + strandat 1072.893 kb on + strand, within Rv0959at 1073.339 kb on + strandat 1073.339 kb on + strandat 1073.782 kb on - strand, within Rv0960at 1073.825 kb on - strand, within Rv0960at 1073.825 kb on - strand, within Rv0960at 1073.825 kb on - strand, within Rv0960at 1073.825 kb on - strand, within Rv0960at 1073.957 kb on + strandat 1073.971 kb on - strandat 1074.146 kb on + strand, within Rv0961at 1074.146 kb on + strand, within Rv0961at 1074.146 kb on + strand, within Rv0961at 1074.147 kb on - strand, within Rv0961at 1074.192 kb on + strand, within Rv0961at 1074.192 kb on + strand, within Rv0961at 1074.245 kb on + strand, within Rv0961

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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1,070,279 + Rv0958 0.29 +0.0
1,070,570 + Rv0958 0.50 +0.0
1,070,570 + Rv0958 0.50 -0.2
1,070,708 + Rv0958 0.60 -1.8
1,071,205 - +1.8
1,071,206 + +1.0
1,071,207 - -0.2
1,071,260 + +0.0
1,071,328 + -0.2
1,071,328 + -0.5
1,071,329 - -0.1
1,071,333 + -0.5
1,072,893 + Rv0959 0.81 -0.7
1,073,339 + +0.0
1,073,339 + -0.1
1,073,782 - Rv0960 0.62 +0.2
1,073,825 - Rv0960 0.73 -1.5
1,073,825 - Rv0960 0.73 -0.4
1,073,825 - Rv0960 0.73 -0.3
1,073,825 - Rv0960 0.73 -0.3
1,073,957 + -0.6
1,073,971 - +0.4
1,074,146 + Rv0961 0.21 +0.1
1,074,146 + Rv0961 0.21 -0.1
1,074,146 + Rv0961 0.21 -1.4
1,074,147 - Rv0961 0.21 -0.1
1,074,192 + Rv0961 0.34 -1.2
1,074,192 + Rv0961 0.34 +0.1
1,074,245 + Rv0961 0.49 -0.3

Or see this region's nucleotide sequence