Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0753c

Experiment: L-Valine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0752c and Rv0753c are separated by 6 nucleotidesRv0753c and Rv0754 are separated by 205 nucleotides Rv0752c: Rv0752c - Probable acyl-CoA dehydrogenase FadE9, at 843,242 to 844,414 Rv0752c Rv0753c: Rv0753c - Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH), at 844,421 to 845,953 Rv0753c Rv0754: Rv0754 - PE-PGRS family protein PE_PGRS11, at 846,159 to 847,913 Rv0754 Position (kb) 844 845 846Strain fitness (log2 ratio) -1 0 1 2at 843.912 kb on + strand, within Rv0752cat 843.912 kb on + strand, within Rv0752cat 843.913 kb on - strand, within Rv0752cat 844.257 kb on + strand, within Rv0752cat 844.779 kb on + strand, within Rv0753cat 844.780 kb on - strand, within Rv0753cat 844.944 kb on + strand, within Rv0753cat 845.030 kb on - strand, within Rv0753cat 845.250 kb on + strand, within Rv0753cat 845.257 kb on - strand, within Rv0753cat 845.257 kb on - strand, within Rv0753cat 845.550 kb on + strand, within Rv0753cat 845.551 kb on - strand, within Rv0753cat 845.583 kb on + strand, within Rv0753cat 846.054 kb on + strandat 846.131 kb on - strandat 846.133 kb on + strandat 846.133 kb on + strandat 846.133 kb on + strandat 846.153 kb on + strandat 846.298 kb on + strandat 846.417 kb on + strand, within Rv0754at 846.417 kb on + strand, within Rv0754at 846.417 kb on + strand, within Rv0754at 846.417 kb on + strand, within Rv0754at 846.417 kb on + strand, within Rv0754at 846.418 kb on - strand, within Rv0754at 846.418 kb on - strand, within Rv0754at 846.418 kb on - strand, within Rv0754at 846.511 kb on - strand, within Rv0754

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Valine 10 mM (N)
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843,912 + Rv0752c 0.57 -0.0
843,912 + Rv0752c 0.57 -0.4
843,913 - Rv0752c 0.57 +0.5
844,257 + Rv0752c 0.87 -0.4
844,779 + Rv0753c 0.23 -1.7
844,780 - Rv0753c 0.23 -1.4
844,944 + Rv0753c 0.34 -0.5
845,030 - Rv0753c 0.40 -0.6
845,250 + Rv0753c 0.54 -0.5
845,257 - Rv0753c 0.55 -1.3
845,257 - Rv0753c 0.55 +2.4
845,550 + Rv0753c 0.74 -0.5
845,551 - Rv0753c 0.74 -0.5
845,583 + Rv0753c 0.76 -0.7
846,054 + -0.8
846,131 - +0.7
846,133 + +0.3
846,133 + -0.4
846,133 + -0.5
846,153 + +0.4
846,298 + +0.2
846,417 + Rv0754 0.15 -0.3
846,417 + Rv0754 0.15 -0.2
846,417 + Rv0754 0.15 -0.3
846,417 + Rv0754 0.15 +0.7
846,417 + Rv0754 0.15 -0.8
846,418 - Rv0754 0.15 -0.9
846,418 - Rv0754 0.15 +2.1
846,418 - Rv0754 0.15 +0.2
846,511 - Rv0754 0.20 -0.0

Or see this region's nucleotide sequence