Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1140

Experiment: L-Serine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1138c and Rv1139c overlap by 4 nucleotidesRv1139c and Rv1140 are separated by 361 nucleotidesRv1140 and Rv1141c are separated by 7 nucleotidesRv1141c and Rv1142c are separated by 142 nucleotides Rv1138c: Rv1138c - Possible oxidoreductase, at 1,265,472 to 1,266,488 Rv1138c Rv1139c: Rv1139c - Conserved hypothetical membrane protein, at 1,266,485 to 1,266,985 Rv1139c Rv1140: Rv1140 - Probable integral membrane protein, at 1,267,347 to 1,268,195 Rv1140 Rv1141c: Rv1141c - Probable enoyl-CoA hydratase EchA11 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,268,203 to 1,269,009 Rv1141c Rv1142c: Rv1142c - Probable enoyl-CoA hydratase EchA10 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,269,152 to 1,269,958 Rv1142c Position (kb) 1267 1268 1269Strain fitness (log2 ratio) -2 -1 0 1at 1266.488 kb on + strandat 1266.624 kb on + strand, within Rv1139cat 1266.625 kb on - strand, within Rv1139cat 1266.788 kb on + strand, within Rv1139cat 1266.867 kb on + strand, within Rv1139cat 1266.867 kb on + strand, within Rv1139cat 1266.868 kb on - strand, within Rv1139cat 1266.978 kb on + strandat 1266.979 kb on - strandat 1266.979 kb on - strandat 1266.979 kb on - strandat 1266.982 kb on - strandat 1266.982 kb on - strandat 1266.982 kb on - strandat 1266.991 kb on + strandat 1266.991 kb on + strandat 1267.032 kb on + strandat 1267.085 kb on + strandat 1267.086 kb on - strandat 1267.086 kb on - strandat 1267.110 kb on - strandat 1267.319 kb on - strandat 1267.804 kb on + strand, within Rv1140at 1267.805 kb on - strand, within Rv1140at 1268.542 kb on + strand, within Rv1141cat 1268.576 kb on - strand, within Rv1141cat 1268.608 kb on - strand, within Rv1141cat 1268.620 kb on + strand, within Rv1141cat 1268.716 kb on + strand, within Rv1141cat 1268.784 kb on + strand, within Rv1141cat 1268.784 kb on + strand, within Rv1141cat 1268.785 kb on - strand, within Rv1141cat 1268.785 kb on - strand, within Rv1141cat 1268.984 kb on - strandat 1269.022 kb on - strandat 1269.022 kb on - strandat 1269.022 kb on - strandat 1269.050 kb on - strandat 1269.099 kb on + strandat 1269.100 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Serine 10 mM (N)
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1,266,488 + -0.6
1,266,624 + Rv1139c 0.28 -0.1
1,266,625 - Rv1139c 0.28 +0.6
1,266,788 + Rv1139c 0.60 -0.0
1,266,867 + Rv1139c 0.76 -1.1
1,266,867 + Rv1139c 0.76 -0.5
1,266,868 - Rv1139c 0.76 -1.1
1,266,978 + -2.3
1,266,979 - +0.4
1,266,979 - -0.7
1,266,979 - +1.5
1,266,982 - +0.0
1,266,982 - +0.0
1,266,982 - -0.5
1,266,991 + -0.3
1,266,991 + -0.4
1,267,032 + -0.4
1,267,085 + +0.2
1,267,086 - -0.3
1,267,086 - -0.6
1,267,110 - -0.5
1,267,319 - -0.4
1,267,804 + Rv1140 0.54 -0.0
1,267,805 - Rv1140 0.54 -0.0
1,268,542 + Rv1141c 0.42 -0.1
1,268,576 - Rv1141c 0.46 -1.1
1,268,608 - Rv1141c 0.50 -0.4
1,268,620 + Rv1141c 0.52 -0.2
1,268,716 + Rv1141c 0.64 -0.2
1,268,784 + Rv1141c 0.72 -1.5
1,268,784 + Rv1141c 0.72 -0.2
1,268,785 - Rv1141c 0.72 -1.4
1,268,785 - Rv1141c 0.72 +0.0
1,268,984 - -0.4
1,269,022 - +0.2
1,269,022 - -0.0
1,269,022 - -0.6
1,269,050 - -0.1
1,269,099 + +0.3
1,269,100 - +0.1

Or see this region's nucleotide sequence