Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3652

Experiment: L-Serine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3651 and Rv3652 are separated by 753 nucleotidesRv3652 and Rv3653 overlap by 7 nucleotidesRv3653 and Rv3654c are separated by 132 nucleotidesRv3654c and Rv3655c are separated by 8 nucleotides Rv3651: Rv3651 - Conserved hypothetical protein, at 4,091,841 to 4,092,878 Rv3651 Rv3652: Rv3652 - PE-PGRS family-related protein PE_PGRS60, at 4,093,632 to 4,093,946 Rv3652 Rv3653: Rv3653 - PE-PGRS family-related protein PE_PGRS61, at 4,093,940 to 4,094,527 Rv3653 Rv3654c: Rv3654c - Conserved hypothetical protein, at 4,094,660 to 4,094,914 Rv3654c Rv3655c: Rv3655c - Conserved hypothetical protein, at 4,094,923 to 4,095,300 Rv3655c Position (kb) 4093 4094Strain fitness (log2 ratio) -1 0 1at 4093.553 kb on + strandat 4093.638 kb on + strandat 4093.638 kb on + strandat 4093.638 kb on + strandat 4093.792 kb on - strand, within Rv3652at 4093.814 kb on + strand, within Rv3652at 4093.814 kb on + strand, within Rv3652at 4093.815 kb on - strand, within Rv3652at 4094.562 kb on - strandat 4094.585 kb on - strandat 4094.613 kb on - strandat 4094.613 kb on - strandat 4094.650 kb on + strandat 4094.924 kb on + strandat 4094.924 kb on + strandat 4094.929 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Serine 10 mM (N)
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4,093,553 + -0.4
4,093,638 + -0.7
4,093,638 + -0.4
4,093,638 + -0.3
4,093,792 - Rv3652 0.51 -0.0
4,093,814 + Rv3652 0.58 -1.5
4,093,814 + Rv3652 0.58 -0.4
4,093,815 - Rv3652 0.58 -0.8
4,094,562 - -0.3
4,094,585 - -0.2
4,094,613 - -0.7
4,094,613 - -0.2
4,094,650 + -0.6
4,094,924 + -0.3
4,094,924 + -1.0
4,094,929 - -0.3

Or see this region's nucleotide sequence