Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2659c

Experiment: L-Serine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2656c and Rv2657c overlap by 4 nucleotidesRv2657c and Rv2658c are separated by 16 nucleotidesRv2658c and Rv2659c are separated by 2 nucleotidesRv2659c and Rv2660c are separated by 144 nucleotidesRv2660c and Rv2661c overlap by 4 nucleotidesRv2661c and Rv2662 overlap by 95 nucleotides Rv2656c: Rv2656c - Possible PhiRv2 prophage protein, at 2,978,660 to 2,979,052 Rv2656c Rv2657c: Rv2657c - Probable PhiRv2 prophage protein, at 2,979,049 to 2,979,309 Rv2657c Rv2658c: Rv2658c - Possible prophage protein, at 2,979,326 to 2,979,688 Rv2658c Rv2659c: Rv2659c - Probable PhiRv2 prophage integrase, at 2,979,691 to 2,980,818 Rv2659c Rv2660c: Rv2660c - Hypothetical protein, at 2,980,963 to 2,981,190 Rv2660c Rv2661c: Rv2661c - Hypothetical protein, at 2,981,187 to 2,981,576 Rv2661c Rv2662: Rv2662 - Hypothetical protein, at 2,981,482 to 2,981,754 Rv2662 Position (kb) 2979 2980 2981Strain fitness (log2 ratio) -2 -1 0 1 2at 2978.741 kb on + strand, within Rv2656cat 2978.916 kb on + strand, within Rv2656cat 2978.916 kb on + strand, within Rv2656cat 2978.916 kb on + strand, within Rv2656cat 2979.188 kb on + strand, within Rv2657cat 2979.188 kb on + strand, within Rv2657cat 2979.335 kb on + strandat 2979.356 kb on + strandat 2979.356 kb on + strandat 2979.356 kb on + strandat 2979.356 kb on + strandat 2979.356 kb on + strandat 2979.374 kb on + strand, within Rv2658cat 2979.392 kb on + strand, within Rv2658cat 2979.393 kb on - strand, within Rv2658cat 2979.393 kb on - strand, within Rv2658cat 2979.498 kb on + strand, within Rv2658cat 2979.584 kb on + strand, within Rv2658cat 2979.584 kb on + strand, within Rv2658cat 2979.584 kb on + strand, within Rv2658cat 2979.585 kb on - strand, within Rv2658cat 2979.585 kb on - strand, within Rv2658cat 2979.585 kb on - strand, within Rv2658cat 2979.662 kb on - strandat 2979.662 kb on - strandat 2979.662 kb on - strandat 2979.665 kb on + strandat 2979.665 kb on + strandat 2979.665 kb on + strandat 2979.674 kb on - strandat 2979.799 kb on + strandat 2979.914 kb on + strand, within Rv2659cat 2979.914 kb on + strand, within Rv2659cat 2979.926 kb on + strand, within Rv2659cat 2979.943 kb on + strand, within Rv2659cat 2979.943 kb on + strand, within Rv2659cat 2979.943 kb on + strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2980.051 kb on - strand, within Rv2659cat 2980.055 kb on - strand, within Rv2659cat 2980.171 kb on + strand, within Rv2659cat 2980.394 kb on + strand, within Rv2659cat 2980.395 kb on - strand, within Rv2659cat 2980.440 kb on - strand, within Rv2659cat 2980.527 kb on - strand, within Rv2659cat 2980.580 kb on + strand, within Rv2659cat 2980.633 kb on + strand, within Rv2659cat 2980.633 kb on + strand, within Rv2659cat 2980.633 kb on + strand, within Rv2659cat 2980.633 kb on + strand, within Rv2659cat 2980.633 kb on + strand, within Rv2659cat 2980.633 kb on + strand, within Rv2659cat 2980.634 kb on - strand, within Rv2659cat 2980.634 kb on - strand, within Rv2659cat 2980.634 kb on - strand, within Rv2659cat 2980.634 kb on - strand, within Rv2659cat 2980.634 kb on - strand, within Rv2659cat 2980.634 kb on - strand, within Rv2659cat 2980.715 kb on + strandat 2980.715 kb on + strandat 2980.715 kb on + strandat 2980.715 kb on + strandat 2980.716 kb on - strandat 2980.740 kb on - strandat 2980.852 kb on + strandat 2981.043 kb on + strand, within Rv2660cat 2981.044 kb on - strand, within Rv2660cat 2981.044 kb on - strand, within Rv2660cat 2981.044 kb on - strand, within Rv2660cat 2981.416 kb on - strand, within Rv2661cat 2981.466 kb on - strand, within Rv2661cat 2981.584 kb on + strand, within Rv2662at 2981.585 kb on - strand, within Rv2662at 2981.627 kb on + strand, within Rv2662at 2981.808 kb on + strandat 2981.809 kb on - strandat 2981.809 kb on - strandat 2981.809 kb on - strandat 2981.809 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Serine 10 mM (N)
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2,978,741 + Rv2656c 0.21 -0.6
2,978,916 + Rv2656c 0.65 -0.2
2,978,916 + Rv2656c 0.65 -0.1
2,978,916 + Rv2656c 0.65 -2.4
2,979,188 + Rv2657c 0.53 -0.6
2,979,188 + Rv2657c 0.53 +0.7
2,979,335 + +0.6
2,979,356 + -1.0
2,979,356 + -0.3
2,979,356 + -0.8
2,979,356 + -0.6
2,979,356 + -0.7
2,979,374 + Rv2658c 0.13 -0.0
2,979,392 + Rv2658c 0.18 -0.3
2,979,393 - Rv2658c 0.18 +0.4
2,979,393 - Rv2658c 0.18 -0.2
2,979,498 + Rv2658c 0.47 -0.4
2,979,584 + Rv2658c 0.71 -0.1
2,979,584 + Rv2658c 0.71 -0.1
2,979,584 + Rv2658c 0.71 -0.8
2,979,585 - Rv2658c 0.71 -0.1
2,979,585 - Rv2658c 0.71 -0.1
2,979,585 - Rv2658c 0.71 -0.4
2,979,662 - +0.7
2,979,662 - -1.0
2,979,662 - +0.2
2,979,665 + -0.5
2,979,665 + +0.0
2,979,665 + -1.2
2,979,674 - +0.4
2,979,799 + +0.6
2,979,914 + Rv2659c 0.20 +0.0
2,979,914 + Rv2659c 0.20 +0.1
2,979,926 + Rv2659c 0.21 -0.2
2,979,943 + Rv2659c 0.22 +0.1
2,979,943 + Rv2659c 0.22 +0.2
2,979,943 + Rv2659c 0.22 +0.1
2,979,944 - Rv2659c 0.22 -1.1
2,979,944 - Rv2659c 0.22 +0.6
2,979,944 - Rv2659c 0.22 +1.9
2,979,944 - Rv2659c 0.22 -0.2
2,980,051 - Rv2659c 0.32 +0.3
2,980,055 - Rv2659c 0.32 +1.7
2,980,171 + Rv2659c 0.43 -0.4
2,980,394 + Rv2659c 0.62 -0.2
2,980,395 - Rv2659c 0.62 +0.2
2,980,440 - Rv2659c 0.66 -0.4
2,980,527 - Rv2659c 0.74 -0.4
2,980,580 + Rv2659c 0.79 -0.3
2,980,633 + Rv2659c 0.84 +0.4
2,980,633 + Rv2659c 0.84 -0.0
2,980,633 + Rv2659c 0.84 -0.5
2,980,633 + Rv2659c 0.84 +0.3
2,980,633 + Rv2659c 0.84 -0.5
2,980,633 + Rv2659c 0.84 +0.5
2,980,634 - Rv2659c 0.84 -0.1
2,980,634 - Rv2659c 0.84 +0.5
2,980,634 - Rv2659c 0.84 +0.4
2,980,634 - Rv2659c 0.84 -0.4
2,980,634 - Rv2659c 0.84 +0.1
2,980,634 - Rv2659c 0.84 +1.7
2,980,715 + -0.1
2,980,715 + +0.2
2,980,715 + +0.9
2,980,715 + -0.3
2,980,716 - +0.1
2,980,740 - -0.2
2,980,852 + -0.2
2,981,043 + Rv2660c 0.35 +0.8
2,981,044 - Rv2660c 0.36 -0.4
2,981,044 - Rv2660c 0.36 +1.0
2,981,044 - Rv2660c 0.36 -0.1
2,981,416 - Rv2661c 0.59 -0.2
2,981,466 - Rv2661c 0.72 +1.7
2,981,584 + Rv2662 0.37 -0.1
2,981,585 - Rv2662 0.38 -0.0
2,981,627 + Rv2662 0.53 -0.1
2,981,808 + -0.5
2,981,809 - -0.5
2,981,809 - -0.4
2,981,809 - -0.3
2,981,809 - -0.7

Or see this region's nucleotide sequence