Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2046

Experiment: L-Serine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2045c and Rv2046 are separated by 48 nucleotidesRv2046 and Rv2047c are separated by 36 nucleotides Rv2045c: Rv2045c - Carboxylesterase LipT, at 2,289,685 to 2,291,220 Rv2045c Rv2046: Rv2046 - Probable lipoprotein LppI, at 2,291,269 to 2,291,925 Rv2046 Rv2047c: Rv2047c - Conserved hypothetical protein, at 2,291,962 to 2,294,526 Rv2047c Position (kb) 2291 2292Strain fitness (log2 ratio) -4 -3 -2 -1 0 1at 2290.319 kb on + strand, within Rv2045cat 2290.556 kb on - strand, within Rv2045cat 2290.793 kb on + strand, within Rv2045cat 2290.793 kb on + strand, within Rv2045cat 2290.829 kb on + strand, within Rv2045cat 2290.830 kb on - strand, within Rv2045cat 2290.886 kb on - strand, within Rv2045cat 2291.100 kb on - strandat 2291.190 kb on + strandat 2291.191 kb on - strandat 2291.340 kb on - strand, within Rv2046at 2291.557 kb on - strand, within Rv2046at 2291.726 kb on - strand, within Rv2046at 2291.818 kb on + strand, within Rv2046at 2291.957 kb on + strandat 2291.957 kb on + strandat 2291.957 kb on + strandat 2291.958 kb on - strandat 2292.082 kb on - strandat 2292.082 kb on - strandat 2292.183 kb on - strandat 2292.319 kb on + strand, within Rv2047cat 2292.743 kb on + strand, within Rv2047cat 2292.841 kb on + strand, within Rv2047cat 2292.842 kb on - strand, within Rv2047c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Serine 10 mM (N)
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2,290,319 + Rv2045c 0.41 +0.1
2,290,556 - Rv2045c 0.57 +0.3
2,290,793 + Rv2045c 0.72 -0.7
2,290,793 + Rv2045c 0.72 +0.7
2,290,829 + Rv2045c 0.74 -0.2
2,290,830 - Rv2045c 0.75 +0.8
2,290,886 - Rv2045c 0.78 +0.7
2,291,100 - +1.7
2,291,190 + -0.3
2,291,191 - +0.0
2,291,340 - Rv2046 0.11 +1.0
2,291,557 - Rv2046 0.44 -3.1
2,291,726 - Rv2046 0.70 -0.2
2,291,818 + Rv2046 0.84 -0.1
2,291,957 + -0.1
2,291,957 + -0.1
2,291,957 + +0.2
2,291,958 - -0.2
2,292,082 - -1.9
2,292,082 - -3.3
2,292,183 - -3.9
2,292,319 + Rv2047c 0.14 -1.6
2,292,743 + Rv2047c 0.30 -3.9
2,292,841 + Rv2047c 0.34 -2.9
2,292,842 - Rv2047c 0.34 -2.2

Or see this region's nucleotide sequence