Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0260c

Experiment: L-Serine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0258c and Rv0259c are separated by 24 nucleotidesRv0259c and Rv0260c overlap by 4 nucleotidesRv0260c and Rv0261c are separated by 99 nucleotides Rv0258c: Rv0258c - Conserved hypothetical protein, at 310,294 to 310,749 Rv0258c Rv0259c: Rv0259c - Conserved hypothetical protein, at 310,774 to 311,517 Rv0259c Rv0260c: Rv0260c - Possible transcriptional regulatory protein, at 311,514 to 312,659 Rv0260c Rv0261c: Rv0261c - Probable integral membrane nitrite extrusion protein NarK3 (nitrite facilitator), at 312,759 to 314,168 Rv0261c Position (kb) 311 312 313Strain fitness (log2 ratio) -1 0 1at 311.517 kb on + strandat 311.704 kb on - strand, within Rv0260cat 312.009 kb on + strand, within Rv0260cat 312.103 kb on - strand, within Rv0260cat 312.227 kb on + strand, within Rv0260cat 312.227 kb on + strand, within Rv0260cat 312.659 kb on + strandat 312.660 kb on - strandat 312.835 kb on + strandat 312.868 kb on + strandat 312.869 kb on - strandat 313.245 kb on + strand, within Rv0261cat 313.291 kb on + strand, within Rv0261cat 313.291 kb on + strand, within Rv0261cat 313.451 kb on - strand, within Rv0261cat 313.541 kb on - strand, within Rv0261cat 313.582 kb on + strand, within Rv0261cat 313.583 kb on - strand, within Rv0261cat 313.585 kb on - strand, within Rv0261cat 313.585 kb on - strand, within Rv0261c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Serine 10 mM (N)
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311,517 + -0.2
311,704 - Rv0260c 0.17 -0.1
312,009 + Rv0260c 0.43 -0.3
312,103 - Rv0260c 0.51 -0.9
312,227 + Rv0260c 0.62 +0.8
312,227 + Rv0260c 0.62 +0.1
312,659 + +0.4
312,660 - +0.2
312,835 + -0.5
312,868 + +0.0
312,869 - -0.3
313,245 + Rv0261c 0.34 -0.7
313,291 + Rv0261c 0.38 -1.0
313,291 + Rv0261c 0.38 +0.1
313,451 - Rv0261c 0.49 +0.1
313,541 - Rv0261c 0.55 -0.0
313,582 + Rv0261c 0.58 -0.2
313,583 - Rv0261c 0.58 -0.2
313,585 - Rv0261c 0.59 +0.6
313,585 - Rv0261c 0.59 +0.0

Or see this region's nucleotide sequence