Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3494c

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3492c and Rv3493c overlap by 1 nucleotidesRv3493c and Rv3494c overlap by 1 nucleotidesRv3494c and Rv3495c are separated by 10 nucleotides Rv3492c: Rv3492c - Conserved hypothetical Mce associated protein, at 3,910,465 to 3,910,947 Rv3492c Rv3493c: Rv3493c - Conserved hypothetical Mce associated alanine and valine rich protein, at 3,910,947 to 3,911,675 Rv3493c Rv3494c: Rv3494c - Mce-family protein Mce4F, at 3,911,675 to 3,913,369 Rv3494c Rv3495c: Rv3495c - Possible Mce-family lipoprotein LprN (Mce-family lipoprotein Mce4E), at 3,913,380 to 3,914,534 Rv3495c Position (kb) 3911 3912 3913 3914Strain fitness (log2 ratio) -2 -1 0 1 2at 3910.819 kb on + strand, within Rv3492cat 3911.060 kb on + strand, within Rv3493cat 3911.179 kb on - strand, within Rv3493cat 3911.179 kb on - strand, within Rv3493cat 3911.287 kb on + strand, within Rv3493cat 3911.375 kb on + strand, within Rv3493cat 3911.615 kb on + strandat 3911.616 kb on - strandat 3911.616 kb on - strandat 3911.616 kb on - strandat 3911.664 kb on - strandat 3911.677 kb on - strandat 3911.753 kb on - strandat 3911.799 kb on + strandat 3911.799 kb on + strandat 3911.799 kb on + strandat 3911.800 kb on - strandat 3911.800 kb on - strandat 3911.808 kb on + strandat 3911.808 kb on + strandat 3912.100 kb on - strand, within Rv3494cat 3912.199 kb on - strand, within Rv3494cat 3912.218 kb on + strand, within Rv3494cat 3912.218 kb on + strand, within Rv3494cat 3912.264 kb on + strand, within Rv3494cat 3912.316 kb on - strand, within Rv3494cat 3912.316 kb on - strand, within Rv3494cat 3912.316 kb on - strand, within Rv3494cat 3912.316 kb on - strand, within Rv3494cat 3912.316 kb on - strand, within Rv3494cat 3912.452 kb on + strand, within Rv3494cat 3912.528 kb on + strand, within Rv3494cat 3912.789 kb on + strand, within Rv3494cat 3912.790 kb on - strand, within Rv3494cat 3913.037 kb on + strand, within Rv3494cat 3913.038 kb on - strand, within Rv3494cat 3913.038 kb on - strand, within Rv3494cat 3913.047 kb on + strand, within Rv3494cat 3913.048 kb on - strand, within Rv3494cat 3913.076 kb on + strand, within Rv3494cat 3913.212 kb on + strandat 3913.213 kb on - strandat 3913.251 kb on + strandat 3913.288 kb on - strandat 3913.413 kb on - strandat 3913.513 kb on + strand, within Rv3495cat 3913.514 kb on - strand, within Rv3495cat 3913.577 kb on + strand, within Rv3495cat 3913.577 kb on + strand, within Rv3495cat 3913.578 kb on - strand, within Rv3495cat 3913.578 kb on - strand, within Rv3495cat 3913.578 kb on - strand, within Rv3495cat 3913.583 kb on - strand, within Rv3495cat 3913.583 kb on - strand, within Rv3495cat 3913.696 kb on + strand, within Rv3495cat 3914.051 kb on + strand, within Rv3495cat 3914.188 kb on - strand, within Rv3495cat 3914.193 kb on + strand, within Rv3495cat 3914.193 kb on + strand, within Rv3495cat 3914.193 kb on + strand, within Rv3495cat 3914.194 kb on - strand, within Rv3495cat 3914.194 kb on - strand, within Rv3495c

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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3,910,819 + Rv3492c 0.73 -1.3
3,911,060 + Rv3493c 0.16 -1.0
3,911,179 - Rv3493c 0.32 +0.5
3,911,179 - Rv3493c 0.32 -0.8
3,911,287 + Rv3493c 0.47 -0.9
3,911,375 + Rv3493c 0.59 -1.0
3,911,615 + +0.0
3,911,616 - -0.6
3,911,616 - -0.5
3,911,616 - +1.9
3,911,664 - -0.6
3,911,677 - +0.3
3,911,753 - -1.7
3,911,799 + -1.6
3,911,799 + -1.1
3,911,799 + -0.8
3,911,800 - +1.9
3,911,800 - +0.3
3,911,808 + -0.1
3,911,808 + -1.4
3,912,100 - Rv3494c 0.25 -0.7
3,912,199 - Rv3494c 0.31 -1.2
3,912,218 + Rv3494c 0.32 -1.0
3,912,218 + Rv3494c 0.32 -1.1
3,912,264 + Rv3494c 0.35 -1.4
3,912,316 - Rv3494c 0.38 -1.1
3,912,316 - Rv3494c 0.38 -1.2
3,912,316 - Rv3494c 0.38 +0.2
3,912,316 - Rv3494c 0.38 +0.3
3,912,316 - Rv3494c 0.38 -0.9
3,912,452 + Rv3494c 0.46 -0.8
3,912,528 + Rv3494c 0.50 +1.5
3,912,789 + Rv3494c 0.66 -1.2
3,912,790 - Rv3494c 0.66 -0.5
3,913,037 + Rv3494c 0.80 -2.7
3,913,038 - Rv3494c 0.80 -0.3
3,913,038 - Rv3494c 0.80 -0.5
3,913,047 + Rv3494c 0.81 -1.1
3,913,048 - Rv3494c 0.81 -1.7
3,913,076 + Rv3494c 0.83 -0.3
3,913,212 + -1.3
3,913,213 - -0.7
3,913,251 + -0.5
3,913,288 - -1.1
3,913,413 - -0.1
3,913,513 + Rv3495c 0.12 -1.6
3,913,514 - Rv3495c 0.12 -1.0
3,913,577 + Rv3495c 0.17 -0.4
3,913,577 + Rv3495c 0.17 -1.3
3,913,578 - Rv3495c 0.17 -1.0
3,913,578 - Rv3495c 0.17 -1.1
3,913,578 - Rv3495c 0.17 -0.7
3,913,583 - Rv3495c 0.18 +1.0
3,913,583 - Rv3495c 0.18 -1.4
3,913,696 + Rv3495c 0.27 -1.6
3,914,051 + Rv3495c 0.58 -0.6
3,914,188 - Rv3495c 0.70 -0.8
3,914,193 + Rv3495c 0.70 -0.6
3,914,193 + Rv3495c 0.70 -0.9
3,914,193 + Rv3495c 0.70 +1.9
3,914,194 - Rv3495c 0.70 -0.5
3,914,194 - Rv3495c 0.70 -1.2

Or see this region's nucleotide sequence