Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2997

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2996c and Rv2997 are separated by 29 nucleotidesRv2997 and Rv2998 are separated by 273 nucleotidesRv2998 and Rv2998A overlap by 52 nucleotides Rv2996c: Rv2996c - Probable D-3-phosphoglycerate dehydrogenase SerA1 (PGDH), at 3,353,483 to 3,355,069 Rv2996c Rv2997: Rv2997 - Possible alanine rich dehydrogenase, at 3,355,099 to 3,356,541 Rv2997 Rv2998: Rv2998 - Hypothetical protein, at 3,356,815 to 3,357,276 Rv2998 Rv2998A: Rv2998A - Conserved hypothetical protein, at 3,357,225 to 3,357,428 Rv2998A Position (kb) 3355 3356 3357Strain fitness (log2 ratio) -1 0 1at 3355.081 kb on - strandat 3355.251 kb on - strand, within Rv2997at 3355.316 kb on + strand, within Rv2997at 3356.162 kb on - strand, within Rv2997at 3356.306 kb on - strand, within Rv2997at 3356.407 kb on + strandat 3356.937 kb on + strand, within Rv2998at 3356.938 kb on - strand, within Rv2998at 3356.938 kb on - strand, within Rv2998at 3356.938 kb on - strand, within Rv2998at 3357.234 kb on + strandat 3357.458 kb on - strandat 3357.458 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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3,355,081 - -0.0
3,355,251 - Rv2997 0.11 -0.5
3,355,316 + Rv2997 0.15 -0.6
3,356,162 - Rv2997 0.74 -1.0
3,356,306 - Rv2997 0.84 -0.7
3,356,407 + +0.4
3,356,937 + Rv2998 0.26 -0.3
3,356,938 - Rv2998 0.27 +0.2
3,356,938 - Rv2998 0.27 -0.2
3,356,938 - Rv2998 0.27 -0.4
3,357,234 + +0.1
3,357,458 - +0.3
3,357,458 - -0.3

Or see this region's nucleotide sequence