Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2614A

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2614c and Rv2614A are separated by 108 nucleotidesRv2614A and Rv2615c overlap by 4 nucleotides Rv2614c: Rv2614c - Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase), at 2,941,189 to 2,943,267 Rv2614c Rv2614A: Rv2614A - Conserved hypothetical protein, at 2,943,376 to 2,943,603 Rv2614A Rv2615c: Rv2615c - PE-PGRS family protein PE_PGRS45, at 2,943,600 to 2,944,985 Rv2615c Position (kb) 2943 2944Strain fitness (log2 ratio) -1 0 1at 2943.340 kb on + strandat 2943.341 kb on - strandat 2943.923 kb on + strand, within Rv2615cat 2943.979 kb on + strand, within Rv2615cat 2943.980 kb on - strand, within Rv2615cat 2943.980 kb on - strand, within Rv2615cat 2943.980 kb on - strand, within Rv2615c

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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2,943,340 + -0.2
2,943,341 - -0.4
2,943,923 + Rv2615c 0.23 +0.2
2,943,979 + Rv2615c 0.27 -0.3
2,943,980 - Rv2615c 0.27 +0.1
2,943,980 - Rv2615c 0.27 +0.7
2,943,980 - Rv2615c 0.27 -0.4

Or see this region's nucleotide sequence