Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2606c

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2604c and Rv2605c are separated by 7 nucleotidesRv2605c and Rv2606c are separated by 28 nucleotidesRv2606c and Rv2607 are separated by 127 nucleotidesRv2607 and Rv2608 are separated by 173 nucleotides Rv2604c: Rv2604c - Probable glutamine amidotransferase SnoP, at 2,931,693 to 2,932,289 Rv2604c Rv2605c: Rv2605c - Probable acyl-CoA thioesterase II TesB2 (TEII), at 2,932,297 to 2,933,142 Rv2605c Rv2606c: Rv2606c - Possible pyridoxine biosynthesis protein SnzP, at 2,933,171 to 2,934,070 Rv2606c Rv2607: Rv2607 - Probable pyridoxamine 5'-phosphate oxidase PdxH (PNP/PMP oxidase) (pyridoxinephosphate oxidase) (PNPOX) (pyridoxine 5'-phosphate oxidase), at 2,934,198 to 2,934,872 Rv2607 Rv2608: Rv2608 - PPE family protein PPE42, at 2,935,046 to 2,936,788 Rv2608 Position (kb) 2933 2934 2935Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2932.440 kb on - strand, within Rv2605cat 2932.440 kb on - strand, within Rv2605cat 2932.789 kb on - strand, within Rv2605cat 2932.846 kb on + strand, within Rv2605cat 2932.985 kb on + strand, within Rv2605cat 2932.985 kb on + strand, within Rv2605cat 2933.032 kb on + strand, within Rv2605cat 2933.033 kb on - strand, within Rv2605cat 2933.460 kb on - strand, within Rv2606cat 2933.757 kb on + strand, within Rv2606cat 2933.758 kb on - strand, within Rv2606cat 2933.758 kb on - strand, within Rv2606cat 2933.758 kb on - strand, within Rv2606cat 2933.815 kb on + strand, within Rv2606cat 2933.816 kb on - strand, within Rv2606cat 2934.055 kb on + strandat 2934.092 kb on + strandat 2934.093 kb on - strandat 2934.093 kb on - strandat 2934.097 kb on + strandat 2934.097 kb on + strandat 2934.163 kb on - strandat 2934.163 kb on - strandat 2934.478 kb on - strand, within Rv2607at 2934.478 kb on - strand, within Rv2607at 2934.478 kb on - strand, within Rv2607at 2934.516 kb on + strand, within Rv2607at 2934.517 kb on - strand, within Rv2607at 2934.517 kb on - strand, within Rv2607at 2934.540 kb on + strand, within Rv2607at 2934.547 kb on + strand, within Rv2607at 2934.547 kb on + strand, within Rv2607at 2934.565 kb on + strand, within Rv2607at 2934.565 kb on + strand, within Rv2607at 2934.565 kb on + strand, within Rv2607at 2934.565 kb on + strand, within Rv2607at 2934.565 kb on + strand, within Rv2607at 2934.566 kb on - strand, within Rv2607at 2934.566 kb on - strand, within Rv2607at 2934.601 kb on + strand, within Rv2607at 2934.601 kb on + strand, within Rv2607at 2934.602 kb on - strand, within Rv2607at 2934.602 kb on - strand, within Rv2607at 2934.609 kb on + strand, within Rv2607at 2934.609 kb on + strand, within Rv2607at 2934.610 kb on - strand, within Rv2607at 2934.939 kb on + strandat 2934.939 kb on + strandat 2934.992 kb on + strandat 2935.037 kb on + strandat 2935.037 kb on + strandat 2935.037 kb on + strandat 2935.038 kb on - strandat 2935.038 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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2,932,440 - Rv2605c 0.17 +0.1
2,932,440 - Rv2605c 0.17 +0.1
2,932,789 - Rv2605c 0.58 -0.6
2,932,846 + Rv2605c 0.65 -0.9
2,932,985 + Rv2605c 0.81 +0.5
2,932,985 + Rv2605c 0.81 -0.1
2,933,032 + Rv2605c 0.87 -0.5
2,933,033 - Rv2605c 0.87 +0.1
2,933,460 - Rv2606c 0.32 +1.8
2,933,757 + Rv2606c 0.65 -1.5
2,933,758 - Rv2606c 0.65 -1.1
2,933,758 - Rv2606c 0.65 -2.9
2,933,758 - Rv2606c 0.65 -0.5
2,933,815 + Rv2606c 0.72 -2.1
2,933,816 - Rv2606c 0.72 -1.5
2,934,055 + -2.0
2,934,092 + +0.8
2,934,093 - +0.1
2,934,093 - -0.2
2,934,097 + -0.1
2,934,097 + -0.2
2,934,163 - -1.2
2,934,163 - -0.6
2,934,478 - Rv2607 0.41 -0.6
2,934,478 - Rv2607 0.41 +0.4
2,934,478 - Rv2607 0.41 -0.5
2,934,516 + Rv2607 0.47 -0.0
2,934,517 - Rv2607 0.47 +1.8
2,934,517 - Rv2607 0.47 +0.6
2,934,540 + Rv2607 0.51 -0.2
2,934,547 + Rv2607 0.52 -0.3
2,934,547 + Rv2607 0.52 -1.4
2,934,565 + Rv2607 0.54 -0.4
2,934,565 + Rv2607 0.54 +1.3
2,934,565 + Rv2607 0.54 -0.0
2,934,565 + Rv2607 0.54 +0.2
2,934,565 + Rv2607 0.54 +0.2
2,934,566 - Rv2607 0.55 +0.3
2,934,566 - Rv2607 0.55 +1.1
2,934,601 + Rv2607 0.60 -0.4
2,934,601 + Rv2607 0.60 +1.2
2,934,602 - Rv2607 0.60 -0.5
2,934,602 - Rv2607 0.60 -0.5
2,934,609 + Rv2607 0.61 +0.1
2,934,609 + Rv2607 0.61 +0.2
2,934,610 - Rv2607 0.61 +1.2
2,934,939 + -0.2
2,934,939 + -0.5
2,934,992 + +0.4
2,935,037 + +1.8
2,935,037 + -0.1
2,935,037 + -0.3
2,935,038 - -0.6
2,935,038 - -0.2

Or see this region's nucleotide sequence