Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3204

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3203 and Rv3204 are separated by 2 nucleotidesRv3204 and Rv3205c are separated by 6 nucleotidesRv3205c and Rv3206c are separated by 26 nucleotides Rv3203: Rv3203 - Possible lipase LipV, at 3,580,638 to 3,581,312 Rv3203 Rv3204: Rv3204 - Possible DNA-methyltransferase (modification methylase), at 3,581,315 to 3,581,620 Rv3204 Rv3205c: Rv3205c - Conserved protein, at 3,581,627 to 3,582,505 Rv3205c Rv3206c: Rv3206c - Probable molybdenum cofactor biosynthesis protein MoeB1 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase), at 3,582,532 to 3,583,710 Rv3206c Position (kb) 3581 3582Strain fitness (log2 ratio) -1 0 1 2at 3580.324 kb on - strandat 3580.394 kb on + strandat 3580.493 kb on + strandat 3580.494 kb on - strandat 3580.545 kb on + strandat 3580.545 kb on + strandat 3580.683 kb on - strandat 3580.683 kb on - strandat 3580.805 kb on + strand, within Rv3203at 3580.806 kb on - strand, within Rv3203at 3581.166 kb on + strand, within Rv3203at 3581.166 kb on + strand, within Rv3203at 3581.206 kb on + strand, within Rv3203at 3581.225 kb on - strand, within Rv3203at 3581.227 kb on + strand, within Rv3203at 3581.227 kb on + strand, within Rv3203at 3581.394 kb on - strand, within Rv3204at 3581.623 kb on - strandat 3582.494 kb on - strandat 3582.494 kb on - strandat 3582.513 kb on + strandat 3582.513 kb on + strandat 3582.525 kb on - strandat 3582.533 kb on + strandat 3582.534 kb on - strandat 3582.536 kb on + strandat 3582.536 kb on + strandat 3582.537 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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3,580,324 - +0.2
3,580,394 + +1.1
3,580,493 + +0.2
3,580,494 - -0.5
3,580,545 + -0.2
3,580,545 + -0.5
3,580,683 - -0.3
3,580,683 - +0.1
3,580,805 + Rv3203 0.25 -0.0
3,580,806 - Rv3203 0.25 +0.0
3,581,166 + Rv3203 0.78 -0.4
3,581,166 + Rv3203 0.78 +0.9
3,581,206 + Rv3203 0.84 -0.6
3,581,225 - Rv3203 0.87 -0.5
3,581,227 + Rv3203 0.87 +0.0
3,581,227 + Rv3203 0.87 -0.1
3,581,394 - Rv3204 0.26 -0.6
3,581,623 - -0.3
3,582,494 - -0.2
3,582,494 - +0.2
3,582,513 + +0.3
3,582,513 + -0.0
3,582,525 - -0.3
3,582,533 + +0.2
3,582,534 - +1.1
3,582,536 + +0.8
3,582,536 + +1.8
3,582,537 - -0.2

Or see this region's nucleotide sequence