Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3081

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3080c and Rv3081 are separated by 51 nucleotidesRv3081 and Rv3082c are separated by 125 nucleotides Rv3080c: Rv3080c - Serine/threonine-protein kinase transcriptional regulatory protein PknK (protein kinase K) (STPK K), at 3,442,656 to 3,445,988 Rv3080c Rv3081: Rv3081 - Conserved hypothetical protein, at 3,446,040 to 3,447,278 Rv3081 Rv3082c: Rv3082c - Virulence-regulating transcriptional regulator VirS (AraC/XylS family), at 3,447,404 to 3,448,426 Rv3082c Position (kb) 3446 3447 3448Strain fitness (log2 ratio) -1 0 1 2 3at 3445.526 kb on + strand, within Rv3080cat 3445.527 kb on - strand, within Rv3080cat 3445.675 kb on + strandat 3445.676 kb on - strandat 3446.000 kb on - strandat 3446.053 kb on - strandat 3446.249 kb on + strand, within Rv3081at 3447.076 kb on + strand, within Rv3081at 3447.193 kb on + strandat 3447.277 kb on - strandat 3447.287 kb on + strandat 3447.426 kb on + strandat 3447.426 kb on + strandat 3447.529 kb on - strand, within Rv3082cat 3447.549 kb on + strand, within Rv3082cat 3447.549 kb on + strand, within Rv3082cat 3447.550 kb on - strand, within Rv3082cat 3447.551 kb on - strand, within Rv3082cat 3447.747 kb on + strand, within Rv3082cat 3447.869 kb on - strand, within Rv3082cat 3448.111 kb on - strand, within Rv3082c

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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3,445,526 + Rv3080c 0.86 +0.8
3,445,527 - Rv3080c 0.86 +0.2
3,445,675 + -0.2
3,445,676 - +0.2
3,446,000 - -0.6
3,446,053 - -0.9
3,446,249 + Rv3081 0.17 -1.5
3,447,076 + Rv3081 0.84 -0.4
3,447,193 + +2.8
3,447,277 - -1.0
3,447,287 + -0.5
3,447,426 + +0.0
3,447,426 + -0.0
3,447,529 - Rv3082c 0.12 -1.6
3,447,549 + Rv3082c 0.14 -1.1
3,447,549 + Rv3082c 0.14 -0.5
3,447,550 - Rv3082c 0.14 +0.4
3,447,551 - Rv3082c 0.14 +0.3
3,447,747 + Rv3082c 0.34 -0.1
3,447,869 - Rv3082c 0.45 -0.3
3,448,111 - Rv3082c 0.69 +0.0

Or see this region's nucleotide sequence