Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2190c

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2188c and Rv2189c are separated by 96 nucleotidesRv2189c and Rv2190c are separated by 94 nucleotidesRv2190c and Rv2191 are separated by 546 nucleotides Rv2188c: Rv2188c - Mannosyltransferase PimB, at 2,449,993 to 2,451,150 Rv2188c Rv2189c: Rv2189c - Conserved hypothetical protein, at 2,451,247 to 2,452,020 Rv2189c Rv2190c: Rv2190c - Conserved hypothetical protein, at 2,452,115 to 2,453,272 Rv2190c Rv2191: Rv2191 - Conserved hypothetical protein, at 2,453,819 to 2,455,756 Rv2191 Position (kb) 2452 2453 2454Strain fitness (log2 ratio) -1 0 1 2at 2451.249 kb on - strandat 2451.256 kb on + strandat 2451.257 kb on - strandat 2451.381 kb on + strand, within Rv2189cat 2451.386 kb on + strand, within Rv2189cat 2451.387 kb on - strand, within Rv2189cat 2451.428 kb on + strand, within Rv2189cat 2452.026 kb on + strandat 2452.027 kb on - strandat 2452.183 kb on - strandat 2452.183 kb on - strandat 2452.183 kb on - strandat 2452.219 kb on - strandat 2452.659 kb on + strand, within Rv2190cat 2452.849 kb on + strand, within Rv2190cat 2452.928 kb on - strand, within Rv2190cat 2452.941 kb on + strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2453.286 kb on - strandat 2453.384 kb on + strandat 2453.416 kb on - strandat 2453.416 kb on - strandat 2453.424 kb on + strandat 2453.426 kb on + strandat 2453.427 kb on - strandat 2453.647 kb on + strandat 2453.647 kb on + strandat 2453.648 kb on - strandat 2453.686 kb on - strandat 2453.831 kb on - strandat 2454.039 kb on + strand, within Rv2191at 2454.040 kb on - strand, within Rv2191at 2454.079 kb on - strand, within Rv2191at 2454.146 kb on - strand, within Rv2191at 2454.268 kb on + strand, within Rv2191

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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2,451,249 - -0.9
2,451,256 + -1.4
2,451,257 - -0.8
2,451,381 + Rv2189c 0.17 -0.7
2,451,386 + Rv2189c 0.18 -0.3
2,451,387 - Rv2189c 0.18 -0.5
2,451,428 + Rv2189c 0.23 +0.1
2,452,026 + -0.4
2,452,027 - -0.9
2,452,183 - -1.2
2,452,183 - -1.2
2,452,183 - -0.6
2,452,219 - +0.1
2,452,659 + Rv2190c 0.47 -1.3
2,452,849 + Rv2190c 0.63 +0.2
2,452,928 - Rv2190c 0.70 -1.2
2,452,941 + Rv2190c 0.71 +1.3
2,452,942 - Rv2190c 0.71 -1.0
2,452,942 - Rv2190c 0.71 -1.1
2,452,942 - Rv2190c 0.71 -0.5
2,452,942 - Rv2190c 0.71 -1.0
2,453,286 - -0.4
2,453,384 + -0.8
2,453,416 - -0.0
2,453,416 - +0.1
2,453,424 + -0.7
2,453,426 + -0.7
2,453,427 - -0.2
2,453,647 + +0.7
2,453,647 + +1.7
2,453,648 - -0.4
2,453,686 - -1.3
2,453,831 - +1.0
2,454,039 + Rv2191 0.11 +2.1
2,454,040 - Rv2191 0.11 -0.0
2,454,079 - Rv2191 0.13 -0.7
2,454,146 - Rv2191 0.17 +0.5
2,454,268 + Rv2191 0.23 -1.1

Or see this region's nucleotide sequence