Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2148c

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2146c and Rv2147c are separated by 161 nucleotidesRv2147c and Rv2148c overlap by 4 nucleotidesRv2148c and Rv2149c are separated by 5 nucleotidesRv2149c and Rv2150c are separated by 10 nucleotides Rv2146c: Rv2146c - Possible conserved transmembrane protein, at 2,405,666 to 2,405,956 Rv2146c Rv2147c: Rv2147c - Conserved hypothetical protein, at 2,406,118 to 2,406,843 Rv2147c Rv2148c: Rv2148c - Conserved protein, at 2,406,840 to 2,407,616 Rv2148c Rv2149c: Rv2149c - Conserved protein YfiH, at 2,407,622 to 2,408,374 Rv2149c Rv2150c: Rv2150c - Cell division protein FtsZ, at 2,408,385 to 2,409,524 Rv2150c Position (kb) 2406 2407 2408Strain fitness (log2 ratio) -2 -1 0 1at 2406.101 kb on - strandat 2406.119 kb on + strandat 2406.120 kb on - strandat 2406.120 kb on - strandat 2406.126 kb on - strandat 2406.131 kb on + strandat 2406.131 kb on + strandat 2406.132 kb on - strandat 2406.132 kb on - strandat 2407.169 kb on - strand, within Rv2148cat 2407.169 kb on - strand, within Rv2148cat 2407.377 kb on - strand, within Rv2148cat 2407.488 kb on + strand, within Rv2148cat 2407.860 kb on + strand, within Rv2149cat 2407.861 kb on - strand, within Rv2149cat 2407.861 kb on - strand, within Rv2149cat 2408.072 kb on - strand, within Rv2149cat 2408.072 kb on - strand, within Rv2149cat 2408.107 kb on + strand, within Rv2149cat 2408.108 kb on - strand, within Rv2149cat 2408.338 kb on + strandat 2408.362 kb on + strandat 2408.362 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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2,406,101 - -0.2
2,406,119 + +0.4
2,406,120 - +0.0
2,406,120 - +0.1
2,406,126 - +0.5
2,406,131 + -0.6
2,406,131 + -0.1
2,406,132 - -0.3
2,406,132 - +1.3
2,407,169 - Rv2148c 0.42 -0.7
2,407,169 - Rv2148c 0.42 -0.8
2,407,377 - Rv2148c 0.69 +1.7
2,407,488 + Rv2148c 0.83 +0.7
2,407,860 + Rv2149c 0.32 -1.5
2,407,861 - Rv2149c 0.32 +1.1
2,407,861 - Rv2149c 0.32 +1.7
2,408,072 - Rv2149c 0.60 -0.6
2,408,072 - Rv2149c 0.60 -0.2
2,408,107 + Rv2149c 0.64 -2.1
2,408,108 - Rv2149c 0.65 -1.1
2,408,338 + +0.4
2,408,362 + -0.4
2,408,362 + -0.6

Or see this region's nucleotide sequence