Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1247c

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1245c and Rv1246c are separated by 56 nucleotidesRv1246c and Rv1247c overlap by 4 nucleotidesRv1247c and Rv1248c are separated by 112 nucleotides Rv1245c: Rv1245c - Probable short-chain type dehydrogenase/reductase, at 1,387,798 to 1,388,628 Rv1245c Rv1246c: Rv1246c - Toxin RelE, at 1,388,685 to 1,388,978 Rv1246c Rv1247c: Rv1247c - Antitoxin RelB, at 1,388,975 to 1,389,244 Rv1247c Rv1248c: Rv1248c - Multifunctional alpha-ketoglutarate metabolic enzyme, at 1,389,357 to 1,393,052 Rv1248c Position (kb) 1388 1389 1390Strain fitness (log2 ratio) -2 -1 0 1 2at 1387.987 kb on - strand, within Rv1245cat 1388.367 kb on - strand, within Rv1245cat 1388.367 kb on - strand, within Rv1245cat 1388.417 kb on - strand, within Rv1245cat 1388.438 kb on - strand, within Rv1245cat 1388.438 kb on - strand, within Rv1245cat 1388.633 kb on + strandat 1388.633 kb on + strandat 1388.633 kb on + strandat 1388.633 kb on + strandat 1388.634 kb on - strandat 1388.686 kb on + strandat 1388.776 kb on + strand, within Rv1246cat 1388.776 kb on + strand, within Rv1246cat 1388.789 kb on - strand, within Rv1246cat 1388.849 kb on + strand, within Rv1246cat 1388.850 kb on - strand, within Rv1246cat 1388.850 kb on - strand, within Rv1246cat 1388.861 kb on + strand, within Rv1246cat 1388.862 kb on - strand, within Rv1246cat 1388.862 kb on - strand, within Rv1246cat 1388.988 kb on + strandat 1389.131 kb on + strand, within Rv1247cat 1389.131 kb on + strand, within Rv1247cat 1389.261 kb on - strandat 1389.281 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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1,387,987 - Rv1245c 0.23 -0.3
1,388,367 - Rv1245c 0.68 +0.3
1,388,367 - Rv1245c 0.68 -1.2
1,388,417 - Rv1245c 0.74 +1.8
1,388,438 - Rv1245c 0.77 +0.3
1,388,438 - Rv1245c 0.77 -0.9
1,388,633 + -0.2
1,388,633 + -0.3
1,388,633 + -0.6
1,388,633 + +0.1
1,388,634 - -1.7
1,388,686 + +1.8
1,388,776 + Rv1246c 0.31 -0.4
1,388,776 + Rv1246c 0.31 +0.0
1,388,789 - Rv1246c 0.35 +0.1
1,388,849 + Rv1246c 0.56 -0.7
1,388,850 - Rv1246c 0.56 -0.2
1,388,850 - Rv1246c 0.56 -0.2
1,388,861 + Rv1246c 0.60 -0.5
1,388,862 - Rv1246c 0.60 -0.7
1,388,862 - Rv1246c 0.60 -0.2
1,388,988 + +0.8
1,389,131 + Rv1247c 0.58 -0.7
1,389,131 + Rv1247c 0.58 -1.0
1,389,261 - -1.8
1,389,281 + -0.3

Or see this region's nucleotide sequence