Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0520

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0519c and Rv0520 are separated by 180 nucleotidesRv0520 and Rv0521 overlap by 8 nucleotidesRv0521 and Rv0522 are separated by 134 nucleotides Rv0519c: Rv0519c - Possible conserved membrane protein, at 611,172 to 612,074 Rv0519c Rv0520: Rv0520 - Possible methyltransferase/methylase (fragment), at 612,255 to 612,605 Rv0520 Rv0521: Rv0521 - Possible methyltransferase/methylase (fragment), at 612,598 to 612,903 Rv0521 Rv0522: Rv0522 - Probable GABA permease GabP (4-amino butyrate transport carrier) (GAMA-aminobutyrate permease), at 613,038 to 614,342 Rv0522 Position (kb) 612 613Strain fitness (log2 ratio) -2 -1 0 1 2at 611.300 kb on - strand, within Rv0519cat 611.380 kb on + strand, within Rv0519cat 611.381 kb on - strand, within Rv0519cat 611.507 kb on - strand, within Rv0519cat 611.553 kb on - strand, within Rv0519cat 611.632 kb on + strand, within Rv0519cat 611.632 kb on + strand, within Rv0519cat 611.633 kb on - strand, within Rv0519cat 612.193 kb on - strandat 612.254 kb on + strandat 612.255 kb on - strandat 612.314 kb on + strand, within Rv0520at 612.314 kb on + strand, within Rv0520at 612.315 kb on - strand, within Rv0520at 612.400 kb on - strand, within Rv0520at 612.555 kb on + strand, within Rv0520at 612.597 kb on + strandat 612.598 kb on - strandat 612.598 kb on - strandat 612.674 kb on - strand, within Rv0521at 612.674 kb on - strand, within Rv0521at 612.759 kb on - strand, within Rv0521at 612.846 kb on - strand, within Rv0521at 612.956 kb on - strandat 612.988 kb on + strandat 612.988 kb on + strandat 612.989 kb on - strandat 612.993 kb on - strandat 613.047 kb on - strandat 613.128 kb on + strandat 613.219 kb on - strand, within Rv0522at 613.269 kb on + strand, within Rv0522at 613.328 kb on - strand, within Rv0522

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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611,300 - Rv0519c 0.14 -0.8
611,380 + Rv0519c 0.23 +0.8
611,381 - Rv0519c 0.23 -0.2
611,507 - Rv0519c 0.37 -0.1
611,553 - Rv0519c 0.42 -0.1
611,632 + Rv0519c 0.51 -0.2
611,632 + Rv0519c 0.51 +0.6
611,633 - Rv0519c 0.51 -1.2
612,193 - +0.4
612,254 + -0.2
612,255 - -0.8
612,314 + Rv0520 0.17 -1.9
612,314 + Rv0520 0.17 -0.8
612,315 - Rv0520 0.17 -0.8
612,400 - Rv0520 0.41 -0.9
612,555 + Rv0520 0.85 +2.4
612,597 + +1.8
612,598 - +0.6
612,598 - -0.2
612,674 - Rv0521 0.25 -0.6
612,674 - Rv0521 0.25 -0.9
612,759 - Rv0521 0.53 -0.2
612,846 - Rv0521 0.81 -0.3
612,956 - +0.1
612,988 + -0.0
612,988 + -0.5
612,989 - -0.6
612,993 - +0.5
613,047 - -0.4
613,128 + -0.0
613,219 - Rv0522 0.14 +0.1
613,269 + Rv0522 0.18 -0.1
613,328 - Rv0522 0.22 +0.8

Or see this region's nucleotide sequence