Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0202c

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0200 and Rv0201c overlap by 4 nucleotidesRv0201c and Rv0202c overlap by 4 nucleotidesRv0202c and Rv0203 are separated by 221 nucleotidesRv0203 and Rv0204c are separated by 51 nucleotides Rv0200: Rv0200 - Possible conserved transmembrane protein, at 237,206 to 237,895 Rv0200 Rv0201c: Rv0201c - Conserved protein, at 237,892 to 238,395 Rv0201c Rv0202c: Rv0202c - Probable conserved transmembrane transport protein MmpL11, at 238,392 to 241,292 Rv0202c Rv0203: Rv0203 - Possible exported protein, at 241,514 to 241,924 Rv0203 Rv0204c: Rv0204c - Probable conserved transmembrane protein, at 241,976 to 243,214 Rv0204c Position (kb) 238 239 240 241 242Strain fitness (log2 ratio) -4 -3 -2 -1 0 1at 237.659 kb on + strand, within Rv0200at 237.659 kb on + strand, within Rv0200at 237.659 kb on + strand, within Rv0200at 238.123 kb on - strand, within Rv0201cat 238.243 kb on + strand, within Rv0201cat 238.300 kb on - strand, within Rv0201cat 238.573 kb on + strandat 238.623 kb on - strandat 238.961 kb on + strand, within Rv0202cat 238.961 kb on + strand, within Rv0202cat 239.302 kb on - strand, within Rv0202cat 239.392 kb on + strand, within Rv0202cat 239.465 kb on - strand, within Rv0202cat 239.465 kb on - strand, within Rv0202cat 239.465 kb on - strand, within Rv0202cat 239.591 kb on - strand, within Rv0202cat 239.856 kb on + strand, within Rv0202cat 239.970 kb on - strand, within Rv0202cat 240.303 kb on + strand, within Rv0202cat 240.303 kb on + strand, within Rv0202cat 240.304 kb on - strand, within Rv0202cat 240.403 kb on + strand, within Rv0202cat 240.404 kb on - strand, within Rv0202cat 240.404 kb on - strand, within Rv0202cat 240.547 kb on + strand, within Rv0202cat 240.547 kb on + strand, within Rv0202cat 240.731 kb on + strand, within Rv0202cat 240.817 kb on + strand, within Rv0202cat 240.817 kb on + strand, within Rv0202cat 240.818 kb on - strand, within Rv0202cat 240.818 kb on - strand, within Rv0202cat 240.870 kb on + strand, within Rv0202cat 240.943 kb on + strand, within Rv0202cat 241.014 kb on + strandat 241.015 kb on - strandat 241.055 kb on - strandat 241.058 kb on + strandat 241.059 kb on - strandat 241.059 kb on - strandat 241.183 kb on - strandat 241.210 kb on + strandat 241.210 kb on + strandat 241.348 kb on - strandat 241.558 kb on - strand, within Rv0203at 241.691 kb on + strand, within Rv0203at 241.692 kb on - strand, within Rv0203at 241.799 kb on - strand, within Rv0203at 241.923 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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237,659 + Rv0200 0.66 -1.2
237,659 + Rv0200 0.66 -0.7
237,659 + Rv0200 0.66 -0.5
238,123 - Rv0201c 0.46 -0.6
238,243 + Rv0201c 0.70 -0.1
238,300 - Rv0201c 0.81 -1.4
238,573 + -0.7
238,623 - -1.4
238,961 + Rv0202c 0.20 -2.0
238,961 + Rv0202c 0.20 -1.0
239,302 - Rv0202c 0.31 -1.1
239,392 + Rv0202c 0.34 -2.8
239,465 - Rv0202c 0.37 -1.7
239,465 - Rv0202c 0.37 -2.0
239,465 - Rv0202c 0.37 -2.0
239,591 - Rv0202c 0.41 -0.4
239,856 + Rv0202c 0.50 +0.3
239,970 - Rv0202c 0.54 -1.5
240,303 + Rv0202c 0.66 -4.1
240,303 + Rv0202c 0.66 -3.1
240,304 - Rv0202c 0.66 -0.4
240,403 + Rv0202c 0.69 -2.1
240,404 - Rv0202c 0.69 -1.8
240,404 - Rv0202c 0.69 -2.6
240,547 + Rv0202c 0.74 -1.4
240,547 + Rv0202c 0.74 -0.8
240,731 + Rv0202c 0.81 -2.1
240,817 + Rv0202c 0.84 -2.5
240,817 + Rv0202c 0.84 -3.6
240,818 - Rv0202c 0.84 -1.3
240,818 - Rv0202c 0.84 +0.2
240,870 + Rv0202c 0.85 -1.8
240,943 + Rv0202c 0.88 +0.6
241,014 + -2.5
241,015 - -1.4
241,055 - -1.2
241,058 + -3.2
241,059 - -1.2
241,059 - -0.6
241,183 - -2.7
241,210 + +0.3
241,210 + -0.1
241,348 - -0.2
241,558 - Rv0203 0.11 -1.3
241,691 + Rv0203 0.43 -0.4
241,692 - Rv0203 0.43 +0.2
241,799 - Rv0203 0.69 +0.7
241,923 - +0.1

Or see this region's nucleotide sequence