Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0141c

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0139 and Rv0140 are separated by 60 nucleotidesRv0140 and Rv0141c overlap by 20 nucleotidesRv0141c and Rv0142 are separated by 29 nucleotides Rv0139: Rv0139 - Possible oxidoreductase, at 165,827 to 166,849 Rv0139 Rv0140: Rv0140 - Conserved protein, at 166,910 to 167,290 Rv0140 Rv0141c: Rv0141c - Unknown protein, at 167,271 to 167,681 Rv0141c Rv0142: Rv0142 - Conserved hypothetical protein, at 167,711 to 168,637 Rv0142 Position (kb) 167 168Strain fitness (log2 ratio) -1 0 1 2at 166.301 kb on + strand, within Rv0139at 166.302 kb on - strand, within Rv0139at 166.352 kb on + strand, within Rv0139at 166.353 kb on - strand, within Rv0139at 166.520 kb on + strand, within Rv0139at 166.520 kb on + strand, within Rv0139at 166.521 kb on - strand, within Rv0139at 166.521 kb on - strand, within Rv0139at 166.521 kb on - strand, within Rv0139at 166.676 kb on - strand, within Rv0139at 166.863 kb on - strandat 166.986 kb on + strand, within Rv0140at 167.065 kb on + strand, within Rv0140at 167.085 kb on + strand, within Rv0140at 167.120 kb on + strand, within Rv0140at 167.121 kb on - strand, within Rv0140at 167.148 kb on - strand, within Rv0140at 167.148 kb on - strand, within Rv0140at 167.150 kb on + strand, within Rv0140at 167.201 kb on + strand, within Rv0140at 167.202 kb on - strand, within Rv0140at 167.308 kb on - strandat 167.308 kb on - strandat 167.335 kb on + strand, within Rv0141cat 167.398 kb on + strand, within Rv0141cat 167.570 kb on - strand, within Rv0141cat 167.839 kb on + strand, within Rv0142at 167.839 kb on + strand, within Rv0142at 167.840 kb on - strand, within Rv0142at 167.840 kb on - strand, within Rv0142at 167.840 kb on - strand, within Rv0142at 168.158 kb on + strand, within Rv0142at 168.158 kb on + strand, within Rv0142at 168.158 kb on + strand, within Rv0142at 168.384 kb on + strand, within Rv0142at 168.384 kb on + strand, within Rv0142at 168.449 kb on + strand, within Rv0142at 168.635 kb on + strandat 168.636 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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166,301 + Rv0139 0.46 +0.0
166,302 - Rv0139 0.46 -0.3
166,352 + Rv0139 0.51 -0.0
166,353 - Rv0139 0.51 -0.2
166,520 + Rv0139 0.68 -0.8
166,520 + Rv0139 0.68 +0.6
166,521 - Rv0139 0.68 -0.8
166,521 - Rv0139 0.68 -0.4
166,521 - Rv0139 0.68 -0.2
166,676 - Rv0139 0.83 +0.0
166,863 - +0.6
166,986 + Rv0140 0.20 +1.6
167,065 + Rv0140 0.41 +1.1
167,085 + Rv0140 0.46 -0.0
167,120 + Rv0140 0.55 +0.1
167,121 - Rv0140 0.55 +0.2
167,148 - Rv0140 0.62 +0.0
167,148 - Rv0140 0.62 -0.2
167,150 + Rv0140 0.63 -0.2
167,201 + Rv0140 0.76 +0.8
167,202 - Rv0140 0.77 -0.1
167,308 - -0.6
167,308 - -0.4
167,335 + Rv0141c 0.16 -0.5
167,398 + Rv0141c 0.31 -0.1
167,570 - Rv0141c 0.73 -0.4
167,839 + Rv0142 0.14 -0.4
167,839 + Rv0142 0.14 +0.4
167,840 - Rv0142 0.14 -0.1
167,840 - Rv0142 0.14 +1.8
167,840 - Rv0142 0.14 +0.0
168,158 + Rv0142 0.48 -0.1
168,158 + Rv0142 0.48 -0.6
168,158 + Rv0142 0.48 +0.3
168,384 + Rv0142 0.73 -0.4
168,384 + Rv0142 0.73 -0.4
168,449 + Rv0142 0.80 -0.5
168,635 + +0.0
168,636 - -0.6

Or see this region's nucleotide sequence