Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0040c

Experiment: Glycine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0038 and Rv0039c are separated by 91 nucleotidesRv0039c and Rv0040c are separated by 81 nucleotidesRv0040c and Rv0041 are separated by 196 nucleotides Rv0038: Rv0038 - Conserved protein, at 41,304 to 41,912 Rv0038 Rv0039c: Rv0039c - Possible conserved transmembrane protein, at 42,004 to 42,351 Rv0039c Rv0040c: Rv0040c - Secreted proline rich protein Mtc28 (proline rich 28 kDa antigen), at 42,433 to 43,365 Rv0040c Rv0041: Rv0041 - Probable leucyl-tRNA synthetase LeuS (leucine--tRNA ligase) (LEURS), at 43,562 to 46,471 Rv0041 Position (kb) 42 43 44Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 41.496 kb on + strand, within Rv0038at 41.497 kb on - strand, within Rv0038at 41.497 kb on - strand, within Rv0038at 41.633 kb on - strand, within Rv0038at 41.911 kb on - strandat 41.916 kb on - strandat 42.208 kb on + strand, within Rv0039cat 42.209 kb on - strand, within Rv0039cat 42.276 kb on + strand, within Rv0039cat 42.362 kb on + strandat 42.363 kb on - strandat 42.363 kb on - strandat 42.493 kb on + strandat 42.644 kb on + strand, within Rv0040cat 42.644 kb on + strand, within Rv0040cat 42.807 kb on - strand, within Rv0040cat 42.807 kb on - strand, within Rv0040cat 42.852 kb on + strand, within Rv0040cat 42.852 kb on + strand, within Rv0040cat 42.853 kb on - strand, within Rv0040cat 42.854 kb on + strand, within Rv0040cat 42.854 kb on + strand, within Rv0040cat 42.855 kb on - strand, within Rv0040cat 42.855 kb on - strand, within Rv0040cat 42.881 kb on + strand, within Rv0040cat 43.421 kb on + strandat 43.422 kb on - strandat 43.547 kb on + strandat 43.548 kb on - strandat 43.550 kb on - strandat 43.550 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Glycine 10 mM (N)
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41,496 + Rv0038 0.32 -0.0
41,497 - Rv0038 0.32 -0.8
41,497 - Rv0038 0.32 +0.2
41,633 - Rv0038 0.54 +1.1
41,911 - +1.8
41,916 - +0.5
42,208 + Rv0039c 0.59 +0.9
42,209 - Rv0039c 0.59 -0.2
42,276 + Rv0039c 0.78 -0.1
42,362 + +0.0
42,363 - +0.9
42,363 - +0.2
42,493 + -0.7
42,644 + Rv0040c 0.23 -1.3
42,644 + Rv0040c 0.23 -0.9
42,807 - Rv0040c 0.40 -1.0
42,807 - Rv0040c 0.40 -1.0
42,852 + Rv0040c 0.45 -1.1
42,852 + Rv0040c 0.45 -0.2
42,853 - Rv0040c 0.45 -0.6
42,854 + Rv0040c 0.45 -1.3
42,854 + Rv0040c 0.45 -1.7
42,855 - Rv0040c 0.45 -1.3
42,855 - Rv0040c 0.45 -2.8
42,881 + Rv0040c 0.48 -0.7
43,421 + -0.6
43,422 - -0.6
43,547 + +1.1
43,548 - -1.2
43,550 - +1.1
43,550 - -0.8

Or see this region's nucleotide sequence