Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3199c

Experiment: L-Glutamic 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3198c and Rv3198A are separated by 123 nucleotidesRv3198A and Rv3199c are separated by 12 nucleotidesRv3199c and Rv3200c are separated by 58 nucleotides Rv3198c: Rv3198c - Probable ATP-dependent DNA helicase II UvrD2, at 3,569,109 to 3,571,211 Rv3198c Rv3198A: Rv3198A - Possible glutaredoxin protein, at 3,571,335 to 3,571,589 Rv3198A Rv3199c: Rv3199c - Probable NADH pyrophosphatase NudC (NAD+ diphosphatase) (NAD+ pyrophosphatase) (NADP pyrophosphatase), at 3,571,602 to 3,572,543 Rv3199c Rv3200c: Rv3200c - Possible transmembrane cation transporter, at 3,572,602 to 3,573,669 Rv3200c Position (kb) 3571 3572 3573Strain fitness (log2 ratio) -1 0 1 2at 3571.233 kb on - strandat 3571.322 kb on - strandat 3571.359 kb on + strandat 3571.359 kb on + strandat 3571.359 kb on + strandat 3571.360 kb on - strandat 3571.360 kb on - strandat 3571.360 kb on - strandat 3571.360 kb on - strandat 3571.360 kb on - strandat 3571.360 kb on - strandat 3571.360 kb on - strandat 3571.360 kb on - strandat 3571.361 kb on + strand, within Rv3198Aat 3571.362 kb on - strand, within Rv3198Aat 3571.380 kb on + strand, within Rv3198Aat 3571.381 kb on - strand, within Rv3198Aat 3571.426 kb on - strand, within Rv3198Aat 3571.588 kb on - strandat 3571.850 kb on - strand, within Rv3199cat 3572.115 kb on + strand, within Rv3199cat 3572.235 kb on + strand, within Rv3199cat 3572.235 kb on + strand, within Rv3199cat 3572.236 kb on - strand, within Rv3199cat 3572.236 kb on - strand, within Rv3199cat 3572.236 kb on - strand, within Rv3199cat 3572.313 kb on + strand, within Rv3199cat 3572.313 kb on + strand, within Rv3199cat 3572.533 kb on - strandat 3572.533 kb on - strandat 3572.533 kb on - strandat 3572.603 kb on + strandat 3572.624 kb on + strandat 3572.625 kb on - strandat 3572.625 kb on - strandat 3572.625 kb on - strandat 3572.696 kb on - strandat 3572.696 kb on - strandat 3573.160 kb on + strand, within Rv3200cat 3573.226 kb on - strand, within Rv3200cat 3573.226 kb on - strand, within Rv3200cat 3573.428 kb on + strand, within Rv3200cat 3573.429 kb on - strand, within Rv3200cat 3573.429 kb on - strand, within Rv3200cat 3573.495 kb on - strand, within Rv3200c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Glutamic 10 mM (N)
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3,571,233 - -0.4
3,571,322 - +1.2
3,571,359 + -1.6
3,571,359 + +2.2
3,571,359 + -0.1
3,571,360 - -0.3
3,571,360 - -0.3
3,571,360 - -0.6
3,571,360 - -0.3
3,571,360 - -0.1
3,571,360 - +0.6
3,571,360 - -0.4
3,571,360 - -0.3
3,571,361 + Rv3198A 0.10 -0.5
3,571,362 - Rv3198A 0.11 +0.5
3,571,380 + Rv3198A 0.18 +1.9
3,571,381 - Rv3198A 0.18 -0.2
3,571,426 - Rv3198A 0.36 +0.4
3,571,588 - -0.4
3,571,850 - Rv3199c 0.26 +0.1
3,572,115 + Rv3199c 0.54 -0.1
3,572,235 + Rv3199c 0.67 +0.3
3,572,235 + Rv3199c 0.67 -0.5
3,572,236 - Rv3199c 0.67 +0.3
3,572,236 - Rv3199c 0.67 +1.1
3,572,236 - Rv3199c 0.67 +0.8
3,572,313 + Rv3199c 0.75 +0.1
3,572,313 + Rv3199c 0.75 -0.4
3,572,533 - +0.6
3,572,533 - -0.8
3,572,533 - -0.8
3,572,603 + +0.1
3,572,624 + -0.3
3,572,625 - -0.1
3,572,625 - +0.6
3,572,625 - -0.2
3,572,696 - -0.1
3,572,696 - +1.2
3,573,160 + Rv3200c 0.52 -0.3
3,573,226 - Rv3200c 0.58 -0.7
3,573,226 - Rv3200c 0.58 +0.3
3,573,428 + Rv3200c 0.77 +0.3
3,573,429 - Rv3200c 0.77 -0.3
3,573,429 - Rv3200c 0.77 -0.2
3,573,495 - Rv3200c 0.84 -0.4

Or see this region's nucleotide sequence