Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2992c

Experiment: L-Glutamic 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2991 and GFF3112 are separated by 73 nucleotidesGFF3112 and GFF3113 are separated by 39 nucleotidesGFF3113 and Rv2992c are separated by 74 nucleotidesRv2992c and Rv2993c overlap by 4 nucleotidesRv2993c and Rv2994 are separated by 275 nucleotides Rv2991: Rv2991 - Conserved protein, at 3,347,982 to 3,348,473 Rv2991 GFF3112 - tRNA-Glu, at 3,348,547 to 3,348,619 GFF3112 GFF3113 - tRNA-Gln, at 3,348,659 to 3,348,730 GFF3113 Rv2992c: Rv2992c - Glutamyl-tRNA synthetase GltS (glutamate--tRNA ligase) (glutamyl-tRNA synthase) (GLURS), at 3,348,805 to 3,350,277 Rv2992c Rv2993c: Rv2993c - Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase), at 3,350,274 to 3,350,993 Rv2993c Rv2994: Rv2994 - Probable conserved integral membrane protein, at 3,351,269 to 3,352,606 Rv2994 Position (kb) 3348 3349 3350 3351Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3347.818 kb on - strandat 3347.886 kb on - strandat 3347.898 kb on - strandat 3347.913 kb on - strandat 3348.111 kb on + strand, within Rv2991at 3348.222 kb on + strand, within Rv2991at 3348.222 kb on + strand, within Rv2991at 3348.222 kb on + strand, within Rv2991at 3348.223 kb on - strand, within Rv2991at 3348.223 kb on - strand, within Rv2991at 3348.331 kb on - strand, within Rv2991at 3348.471 kb on + strandat 3348.471 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.643 kb on + strandat 3348.644 kb on - strandat 3348.741 kb on - strandat 3350.416 kb on - strand, within Rv2993cat 3350.664 kb on - strand, within Rv2993cat 3350.664 kb on - strand, within Rv2993c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Glutamic 10 mM (N)
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3,347,818 - -0.7
3,347,886 - -0.6
3,347,898 - -0.7
3,347,913 - +2.3
3,348,111 + Rv2991 0.26 -3.1
3,348,222 + Rv2991 0.49 -0.6
3,348,222 + Rv2991 0.49 -1.1
3,348,222 + Rv2991 0.49 +0.5
3,348,223 - Rv2991 0.49 -1.5
3,348,223 - Rv2991 0.49 -0.7
3,348,331 - Rv2991 0.71 +1.2
3,348,471 + -0.5
3,348,471 + -0.1
3,348,643 + +0.0
3,348,643 + -0.4
3,348,643 + +1.6
3,348,643 + +0.2
3,348,643 + +0.3
3,348,643 + -0.8
3,348,644 - -1.9
3,348,741 - -0.9
3,350,416 - Rv2993c 0.20 -0.7
3,350,664 - Rv2993c 0.54 +0.4
3,350,664 - Rv2993c 0.54 +1.6

Or see this region's nucleotide sequence