Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1132

Experiment: L-Glutamic 10 mM (N)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1131 and Rv1132 are separated by 11 nucleotidesRv1132 and Rv1133c are separated by 11 nucleotides Rv1131: Rv1131 - Probable methylcitrate synthase PrpC, at 1,256,132 to 1,257,313 Rv1131 Rv1132: Rv1132 - Conserved membrane protein, at 1,257,325 to 1,259,055 Rv1132 Rv1133c: Rv1133c - Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE (methionine synthase, vitamin-B12 independent isozyme), at 1,259,067 to 1,261,346 Rv1133c Position (kb) 1257 1258 1259 1260Strain fitness (log2 ratio) -3 -2 -1 0 1at 1256.810 kb on + strand, within Rv1131at 1256.811 kb on - strand, within Rv1131at 1257.072 kb on - strand, within Rv1131at 1257.199 kb on + strandat 1257.273 kb on - strandat 1257.312 kb on - strandat 1257.317 kb on + strandat 1257.615 kb on - strand, within Rv1132at 1258.001 kb on + strand, within Rv1132at 1258.002 kb on - strand, within Rv1132at 1258.002 kb on - strand, within Rv1132at 1258.639 kb on + strand, within Rv1132at 1258.719 kb on + strand, within Rv1132at 1258.762 kb on + strand, within Rv1132at 1258.762 kb on + strand, within Rv1132at 1258.950 kb on - strandat 1258.950 kb on - strandat 1258.950 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction L-Glutamic 10 mM (N)
remove
1,256,810 + Rv1131 0.57 -3.1
1,256,811 - Rv1131 0.57 -0.2
1,257,072 - Rv1131 0.80 -0.4
1,257,199 + -0.1
1,257,273 - +0.8
1,257,312 - -0.0
1,257,317 + +0.0
1,257,615 - Rv1132 0.17 -0.5
1,258,001 + Rv1132 0.39 -0.6
1,258,002 - Rv1132 0.39 -0.3
1,258,002 - Rv1132 0.39 -0.2
1,258,639 + Rv1132 0.76 -1.2
1,258,719 + Rv1132 0.81 -1.2
1,258,762 + Rv1132 0.83 +1.4
1,258,762 + Rv1132 0.83 -1.2
1,258,950 - +0.2
1,258,950 - -0.2
1,258,950 - +0.0

Or see this region's nucleotide sequence