Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2486

Experiment: L-Glutamine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2485c and GFF2588 are separated by 187 nucleotidesGFF2588 and Rv2486 are separated by 100 nucleotidesRv2486 and Rv2487c are separated by 180 nucleotides Rv2485c: Rv2485c - Probable carboxylesterase LipQ, at 2,792,723 to 2,793,988 Rv2485c GFF2588 - tRNA-Arg, at 2,794,176 to 2,794,249 GFF2588 Rv2486: Rv2486 - Probable enoyl-CoA hydratase EchA14 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 2,794,350 to 2,795,120 Rv2486 Rv2487c: Rv2487c - PE-PGRS family protein PE_PGRS42, at 2,795,301 to 2,797,385 Rv2487c Position (kb) 2794 2795 2796Strain fitness (log2 ratio) -2 -1 0 1at 2793.369 kb on + strand, within Rv2485cat 2793.369 kb on + strand, within Rv2485cat 2793.369 kb on + strand, within Rv2485cat 2793.370 kb on - strand, within Rv2485cat 2793.611 kb on + strand, within Rv2485cat 2793.671 kb on + strand, within Rv2485cat 2793.671 kb on + strand, within Rv2485cat 2793.672 kb on - strand, within Rv2485cat 2793.672 kb on - strand, within Rv2485cat 2793.672 kb on - strand, within Rv2485cat 2793.780 kb on - strand, within Rv2485cat 2793.988 kb on + strandat 2793.988 kb on + strandat 2793.989 kb on - strandat 2793.989 kb on - strandat 2793.989 kb on - strandat 2793.989 kb on - strandat 2794.089 kb on + strandat 2794.090 kb on - strandat 2794.104 kb on + strandat 2794.154 kb on + strandat 2794.158 kb on + strandat 2794.159 kb on - strandat 2794.159 kb on - strandat 2794.359 kb on + strandat 2794.498 kb on + strand, within Rv2486at 2794.499 kb on - strand, within Rv2486at 2794.507 kb on + strand, within Rv2486at 2794.600 kb on + strand, within Rv2486at 2794.631 kb on + strand, within Rv2486at 2794.631 kb on + strand, within Rv2486at 2794.631 kb on + strand, within Rv2486at 2794.632 kb on - strand, within Rv2486at 2794.637 kb on + strand, within Rv2486at 2794.638 kb on - strand, within Rv2486at 2794.638 kb on - strand, within Rv2486at 2794.835 kb on - strand, within Rv2486at 2795.044 kb on + strandat 2795.118 kb on + strandat 2795.118 kb on + strandat 2795.126 kb on - strandat 2795.212 kb on + strandat 2795.212 kb on + strandat 2795.213 kb on - strandat 2795.236 kb on + strandat 2795.803 kb on - strand, within Rv2487c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Glutamine 10 mM (N)
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2,793,369 + Rv2485c 0.51 -0.2
2,793,369 + Rv2485c 0.51 -1.3
2,793,369 + Rv2485c 0.51 +0.0
2,793,370 - Rv2485c 0.51 -0.2
2,793,611 + Rv2485c 0.70 +0.3
2,793,671 + Rv2485c 0.75 -0.5
2,793,671 + Rv2485c 0.75 -1.1
2,793,672 - Rv2485c 0.75 -0.5
2,793,672 - Rv2485c 0.75 -0.3
2,793,672 - Rv2485c 0.75 +0.2
2,793,780 - Rv2485c 0.83 -0.7
2,793,988 + -0.2
2,793,988 + -1.2
2,793,989 - -0.3
2,793,989 - +0.8
2,793,989 - -0.1
2,793,989 - +0.7
2,794,089 + -0.5
2,794,090 - +0.2
2,794,104 + -0.1
2,794,154 + -1.0
2,794,158 + -0.4
2,794,159 - -0.1
2,794,159 - +0.8
2,794,359 + -0.7
2,794,498 + Rv2486 0.19 -0.1
2,794,499 - Rv2486 0.19 +0.2
2,794,507 + Rv2486 0.20 -0.1
2,794,600 + Rv2486 0.32 -2.0
2,794,631 + Rv2486 0.36 -1.5
2,794,631 + Rv2486 0.36 -0.3
2,794,631 + Rv2486 0.36 +0.0
2,794,632 - Rv2486 0.37 -0.2
2,794,637 + Rv2486 0.37 -0.6
2,794,638 - Rv2486 0.37 -2.4
2,794,638 - Rv2486 0.37 +0.2
2,794,835 - Rv2486 0.63 -0.5
2,795,044 + -0.4
2,795,118 + +0.3
2,795,118 + -0.9
2,795,126 - -0.6
2,795,212 + +0.3
2,795,212 + -0.3
2,795,213 - -0.9
2,795,236 + -0.4
2,795,803 - Rv2487c 0.24 -0.3

Or see this region's nucleotide sequence