Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0540

Experiment: L-Glutamine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0538 and Rv0539 are separated by 56 nucleotidesRv0539 and Rv0540 overlap by 4 nucleotidesRv0540 and Rv0541c are separated by 20 nucleotides Rv0538: Rv0538 - Possible conserved membrane protein, at 630,040 to 631,686 Rv0538 Rv0539: Rv0539 - Probable dolichyl-phosphate sugar synthase (dolichol-phosphate sugar synthetase) (dolichol-phosphate sugar transferase) (sugar phosphoryldolichol synthase), at 631,743 to 632,375 Rv0539 Rv0540: Rv0540 - Conserved hypothetical protein, at 632,372 to 633,034 Rv0540 Rv0541c: Rv0541c - Probable conserved integral membrane protein, at 633,055 to 634,404 Rv0541c Position (kb) 632 633 634Strain fitness (log2 ratio) -1 0 1 2 3at 631.670 kb on + strandat 631.670 kb on + strandat 631.670 kb on + strandat 631.670 kb on + strandat 631.670 kb on + strandat 632.283 kb on + strand, within Rv0539at 632.284 kb on - strand, within Rv0539at 632.552 kb on - strand, within Rv0540at 632.602 kb on + strand, within Rv0540at 632.603 kb on - strand, within Rv0540at 632.827 kb on + strand, within Rv0540at 632.827 kb on + strand, within Rv0540at 633.057 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Glutamine 10 mM (N)
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631,670 + +0.3
631,670 + -0.5
631,670 + -1.6
631,670 + -0.6
631,670 + +0.3
632,283 + Rv0539 0.85 -1.0
632,284 - Rv0539 0.85 +0.1
632,552 - Rv0540 0.27 +0.6
632,602 + Rv0540 0.35 +3.7
632,603 - Rv0540 0.35 -0.3
632,827 + Rv0540 0.69 +0.3
632,827 + Rv0540 0.69 +0.1
633,057 - +2.1

Or see this region's nucleotide sequence