Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3409c

Experiment: L-Aspartic Acid 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3406 and Rv3407 are separated by 34 nucleotidesRv3407 and Rv3408 overlap by 4 nucleotidesRv3408 and Rv3409c are separated by 32 nucleotidesRv3409c and Rv3410c are separated by 55 nucleotides Rv3406: Rv3406 - Probable dioxygenase, at 3,825,330 to 3,826,217 Rv3406 Rv3407: Rv3407 - Possible antitoxin VapB47, at 3,826,252 to 3,826,551 Rv3407 Rv3408: Rv3408 - Possible toxin VapC47. Contains PIN domain., at 3,826,548 to 3,826,958 Rv3408 Rv3409c: Rv3409c - Cholesterol oxidase ChoD (cholesterol-O2 oxidoreductase), at 3,826,991 to 3,828,727 Rv3409c Rv3410c: Rv3410c - Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (imp oxidoreductase) (inosine-5'-monophosphate oxidoreductase) (IMPDH) (IMPD), at 3,828,783 to 3,829,910 Rv3410c Position (kb) 3826 3827 3828 3829Strain fitness (log2 ratio) -2 -1 0 1 2at 3826.054 kb on + strand, within Rv3406at 3826.054 kb on + strand, within Rv3406at 3826.102 kb on - strand, within Rv3406at 3826.175 kb on + strandat 3826.242 kb on - strandat 3826.298 kb on + strand, within Rv3407at 3826.298 kb on + strand, within Rv3407at 3826.298 kb on + strand, within Rv3407at 3826.298 kb on + strand, within Rv3407at 3826.299 kb on - strand, within Rv3407at 3826.554 kb on + strandat 3826.554 kb on + strandat 3826.555 kb on - strandat 3826.555 kb on - strandat 3826.555 kb on - strandat 3826.555 kb on - strandat 3826.555 kb on - strandat 3826.557 kb on - strandat 3826.738 kb on - strand, within Rv3408at 3826.742 kb on - strand, within Rv3408at 3826.742 kb on - strand, within Rv3408at 3826.817 kb on - strand, within Rv3408at 3826.817 kb on - strand, within Rv3408at 3826.817 kb on - strand, within Rv3408at 3826.817 kb on - strand, within Rv3408at 3826.962 kb on + strandat 3827.232 kb on + strand, within Rv3409cat 3827.250 kb on + strand, within Rv3409cat 3827.250 kb on + strand, within Rv3409cat 3827.250 kb on + strand, within Rv3409cat 3827.250 kb on + strand, within Rv3409cat 3827.251 kb on - strand, within Rv3409cat 3827.251 kb on - strand, within Rv3409cat 3827.262 kb on + strand, within Rv3409cat 3827.426 kb on - strand, within Rv3409cat 3827.426 kb on - strand, within Rv3409cat 3827.426 kb on - strand, within Rv3409cat 3827.882 kb on - strand, within Rv3409cat 3828.369 kb on + strand, within Rv3409cat 3828.370 kb on - strand, within Rv3409cat 3828.447 kb on + strand, within Rv3409cat 3828.448 kb on - strand, within Rv3409cat 3828.448 kb on - strand, within Rv3409cat 3828.526 kb on + strand, within Rv3409cat 3828.526 kb on + strand, within Rv3409cat 3828.527 kb on - strand, within Rv3409cat 3828.714 kb on + strandat 3828.736 kb on + strandat 3828.736 kb on + strandat 3828.737 kb on - strandat 3828.737 kb on - strandat 3828.748 kb on + strandat 3828.749 kb on - strandat 3828.749 kb on - strandat 3828.749 kb on - strandat 3828.749 kb on - strandat 3828.763 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid 10 mM (N)
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3,826,054 + Rv3406 0.82 -1.0
3,826,054 + Rv3406 0.82 +0.1
3,826,102 - Rv3406 0.87 -0.1
3,826,175 + -0.5
3,826,242 - +0.1
3,826,298 + Rv3407 0.15 -0.1
3,826,298 + Rv3407 0.15 -0.0
3,826,298 + Rv3407 0.15 -0.1
3,826,298 + Rv3407 0.15 -0.0
3,826,299 - Rv3407 0.16 +0.1
3,826,554 + -0.7
3,826,554 + -0.4
3,826,555 - +0.0
3,826,555 - +0.1
3,826,555 - -0.2
3,826,555 - +0.3
3,826,555 - +0.5
3,826,557 - +0.0
3,826,738 - Rv3408 0.46 +0.3
3,826,742 - Rv3408 0.47 +0.4
3,826,742 - Rv3408 0.47 -0.7
3,826,817 - Rv3408 0.65 -0.6
3,826,817 - Rv3408 0.65 -0.3
3,826,817 - Rv3408 0.65 +0.2
3,826,817 - Rv3408 0.65 +0.1
3,826,962 + -0.3
3,827,232 + Rv3409c 0.14 -2.7
3,827,250 + Rv3409c 0.15 +0.6
3,827,250 + Rv3409c 0.15 +0.3
3,827,250 + Rv3409c 0.15 +0.0
3,827,250 + Rv3409c 0.15 -2.3
3,827,251 - Rv3409c 0.15 -0.2
3,827,251 - Rv3409c 0.15 +0.3
3,827,262 + Rv3409c 0.16 +0.2
3,827,426 - Rv3409c 0.25 +0.0
3,827,426 - Rv3409c 0.25 -0.9
3,827,426 - Rv3409c 0.25 -0.0
3,827,882 - Rv3409c 0.51 +0.6
3,828,369 + Rv3409c 0.79 -0.1
3,828,370 - Rv3409c 0.79 +0.2
3,828,447 + Rv3409c 0.84 -0.0
3,828,448 - Rv3409c 0.84 +0.5
3,828,448 - Rv3409c 0.84 -0.2
3,828,526 + Rv3409c 0.88 -0.1
3,828,526 + Rv3409c 0.88 -0.1
3,828,527 - Rv3409c 0.88 +1.9
3,828,714 + -0.7
3,828,736 + -0.0
3,828,736 + -0.3
3,828,737 - +0.4
3,828,737 - +0.3
3,828,748 + +1.7
3,828,749 - +0.1
3,828,749 - +0.3
3,828,749 - -0.7
3,828,749 - -0.1
3,828,763 - -0.6

Or see this region's nucleotide sequence