Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2845c

Experiment: L-Aspartic Acid 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2843 and Rv2844 overlap by 4 nucleotidesRv2844 and Rv2845c are separated by 0 nucleotidesRv2845c and Rv2846c are separated by 88 nucleotides Rv2843: Rv2843 - Probable conserved transmembrane alanine rich protein, at 3,150,171 to 3,150,716 Rv2843 Rv2844: Rv2844 - Conserved alanine rich protein, at 3,150,713 to 3,151,201 Rv2844 Rv2845c: Rv2845c - Probable prolyl-tRNA synthetase ProS (proline--tRNA ligase) (PRORS) (global RNA synthesis factor) (proline translase), at 3,151,202 to 3,152,950 Rv2845c Rv2846c: Rv2846c - Possible integral membrane efflux protein EfpA, at 3,153,039 to 3,154,631 Rv2846c Position (kb) 3151 3152 3153Strain fitness (log2 ratio) -1 0 1at 3151.199 kb on + strandat 3151.199 kb on + strandat 3151.200 kb on - strandat 3151.200 kb on - strandat 3152.963 kb on + strandat 3152.963 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid 10 mM (N)
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3,151,199 + -0.7
3,151,199 + +0.8
3,151,200 - -0.2
3,151,200 - -0.1
3,152,963 + +0.3
3,152,963 + -0.3

Or see this region's nucleotide sequence