Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0250c

Experiment: L-Aspartic Acid 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0248c and Rv0249c are separated by 30 nucleotidesRv0249c and Rv0250c are separated by 79 nucleotidesRv0250c and Rv0251c are separated by 144 nucleotidesRv0251c and Rv0252 are separated by 213 nucleotides Rv0248c: Rv0248c - Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase), at 298,863 to 300,803 Rv0248c Rv0249c: Rv0249c - Probable succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase), at 300,834 to 301,655 Rv0249c Rv0250c: Rv0250c - Conserved protein, at 301,735 to 302,028 Rv0250c Rv0251c: Rv0251c - Heat shock protein Hsp (heat-stress-induced ribosome-binding protein A), at 302,173 to 302,652 Rv0251c Rv0252: Rv0252 - Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB, at 302,866 to 305,427 Rv0252 Position (kb) 301 302 303Strain fitness (log2 ratio) -2 -1 0 1 2 3at 300.804 kb on - strandat 300.886 kb on + strandat 301.052 kb on - strand, within Rv0249cat 301.186 kb on + strand, within Rv0249cat 301.234 kb on + strand, within Rv0249cat 301.291 kb on + strand, within Rv0249cat 301.347 kb on + strand, within Rv0249cat 301.444 kb on + strand, within Rv0249cat 301.460 kb on - strand, within Rv0249cat 301.513 kb on + strand, within Rv0249cat 301.513 kb on + strand, within Rv0249cat 301.658 kb on - strandat 301.679 kb on + strandat 301.680 kb on - strandat 301.694 kb on + strandat 301.694 kb on + strandat 301.794 kb on - strand, within Rv0250cat 301.855 kb on + strand, within Rv0250cat 301.856 kb on - strand, within Rv0250cat 301.859 kb on + strand, within Rv0250cat 302.054 kb on + strandat 302.066 kb on + strandat 302.080 kb on + strandat 302.080 kb on + strandat 302.080 kb on + strandat 302.080 kb on + strandat 302.081 kb on - strandat 302.081 kb on - strandat 302.081 kb on - strandat 302.081 kb on - strandat 302.085 kb on - strandat 302.085 kb on - strandat 302.085 kb on - strandat 302.174 kb on + strandat 302.174 kb on + strandat 302.175 kb on - strandat 302.223 kb on - strand, within Rv0251cat 302.261 kb on + strand, within Rv0251cat 302.261 kb on + strand, within Rv0251cat 302.261 kb on + strand, within Rv0251cat 302.710 kb on + strandat 302.710 kb on + strandat 302.710 kb on + strandat 302.712 kb on + strandat 302.713 kb on - strandat 302.811 kb on + strandat 302.812 kb on - strandat 302.812 kb on - strandat 302.812 kb on - strandat 302.812 kb on - strandat 302.854 kb on + strandat 302.855 kb on - strandat 302.871 kb on + strandat 302.872 kb on - strandat 302.872 kb on - strandat 303.025 kb on + strandat 303.025 kb on + strandat 303.026 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid 10 mM (N)
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300,804 - -0.7
300,886 + +0.5
301,052 - Rv0249c 0.27 -1.4
301,186 + Rv0249c 0.43 -0.7
301,234 + Rv0249c 0.49 +2.8
301,291 + Rv0249c 0.56 -1.0
301,347 + Rv0249c 0.62 -1.1
301,444 + Rv0249c 0.74 -1.0
301,460 - Rv0249c 0.76 -1.4
301,513 + Rv0249c 0.83 -1.5
301,513 + Rv0249c 0.83 -2.1
301,658 - -1.5
301,679 + -1.1
301,680 - -0.2
301,694 + -0.9
301,694 + +1.8
301,794 - Rv0250c 0.20 -0.2
301,855 + Rv0250c 0.41 -0.6
301,856 - Rv0250c 0.41 -0.0
301,859 + Rv0250c 0.42 +0.0
302,054 + -0.1
302,066 + -0.1
302,080 + +0.8
302,080 + +0.3
302,080 + -1.1
302,080 + -0.4
302,081 - -1.4
302,081 - +1.2
302,081 - +1.8
302,081 - +0.3
302,085 - +0.3
302,085 - +0.1
302,085 - -0.3
302,174 + -0.6
302,174 + -0.2
302,175 - +1.0
302,223 - Rv0251c 0.10 -0.2
302,261 + Rv0251c 0.18 +0.7
302,261 + Rv0251c 0.18 +0.0
302,261 + Rv0251c 0.18 -0.2
302,710 + -0.6
302,710 + -0.1
302,710 + -0.9
302,712 + +0.6
302,713 - -0.1
302,811 + +0.6
302,812 - -0.0
302,812 - +0.2
302,812 - -0.4
302,812 - -0.1
302,854 + -0.0
302,855 - -0.1
302,871 + -1.6
302,872 - -0.4
302,872 - -0.5
303,025 + +0.5
303,025 + -0.6
303,026 - +0.4

Or see this region's nucleotide sequence