Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2475c

Experiment: L-Aspartic Acid 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2473 and Rv2474c are separated by 31 nucleotidesRv2474c and Rv2475c are separated by 5 nucleotidesRv2475c and Rv2476c overlap by 4 nucleotides Rv2473: Rv2473 - Possible alanine and proline rich membrane protein, at 2,775,568 to 2,776,284 Rv2473 Rv2474c: Rv2474c - Conserved hypothetical protein, at 2,776,316 to 2,776,969 Rv2474c Rv2475c: Rv2475c - Conserved protein, at 2,776,975 to 2,777,391 Rv2475c Rv2476c: Rv2476c - Probable NAD-dependent glutamate dehydrogenase Gdh (NAD-Gdh) (NAD-dependent glutamic dehydrogenase), at 2,777,388 to 2,782,262 Rv2476c Position (kb) 2776 2777 2778Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2776.176 kb on - strand, within Rv2473at 2776.195 kb on + strand, within Rv2473at 2776.196 kb on - strand, within Rv2473at 2776.196 kb on - strand, within Rv2473at 2776.223 kb on + strandat 2776.224 kb on - strandat 2776.641 kb on + strand, within Rv2474cat 2776.977 kb on - strandat 2777.000 kb on + strandat 2777.001 kb on - strandat 2777.211 kb on - strand, within Rv2475cat 2777.274 kb on + strand, within Rv2475cat 2777.336 kb on + strand, within Rv2475cat 2777.336 kb on + strand, within Rv2475cat 2777.336 kb on + strand, within Rv2475cat 2777.336 kb on + strand, within Rv2475cat 2777.611 kb on - strandat 2777.735 kb on - strandat 2777.830 kb on + strandat 2777.996 kb on - strand, within Rv2476cat 2778.137 kb on - strand, within Rv2476cat 2778.193 kb on + strand, within Rv2476c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid 10 mM (N)
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2,776,176 - Rv2473 0.85 -0.1
2,776,195 + Rv2473 0.87 -0.2
2,776,196 - Rv2473 0.88 -0.5
2,776,196 - Rv2473 0.88 -0.6
2,776,223 + -0.9
2,776,224 - -0.8
2,776,641 + Rv2474c 0.50 -0.3
2,776,977 - -0.0
2,777,000 + +2.1
2,777,001 - +0.2
2,777,211 - Rv2475c 0.57 -1.1
2,777,274 + Rv2475c 0.72 -1.8
2,777,336 + Rv2475c 0.87 -0.1
2,777,336 + Rv2475c 0.87 -1.5
2,777,336 + Rv2475c 0.87 +0.6
2,777,336 + Rv2475c 0.87 +0.9
2,777,611 - +0.9
2,777,735 - -3.3
2,777,830 + +1.1
2,777,996 - Rv2476c 0.12 -0.7
2,778,137 - Rv2476c 0.15 -1.2
2,778,193 + Rv2476c 0.17 -1.2

Or see this region's nucleotide sequence