Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1982c

Experiment: L-Aspartic Acid 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1981c and Rv1982c are separated by 224 nucleotidesRv1982c and Rv1982A are separated by 8 nucleotidesRv1982A and Rv1983 are separated by 142 nucleotides Rv1981c: Rv1981c - Ribonucleoside-diphosphate reductase (beta chain) NrdF1 (ribonucleotide reductase small subunit) (R2F protein), at 2,224,220 to 2,225,188 Rv1981c Rv1982c: Rv1982c - Possible toxin VapC36. Contains PIN domain., at 2,225,413 to 2,225,832 Rv1982c Rv1982A: Rv1982A - Possible antitoxin VapB36, at 2,225,841 to 2,226,101 Rv1982A Rv1983: Rv1983 - PE-PGRS family protein PE_PGRS35, at 2,226,244 to 2,227,920 Rv1983 Position (kb) 2225 2226Strain fitness (log2 ratio) -1 0 1 2at 2224.413 kb on + strand, within Rv1981cat 2224.413 kb on + strand, within Rv1981cat 2224.413 kb on + strand, within Rv1981cat 2224.413 kb on + strand, within Rv1981cat 2224.414 kb on - strand, within Rv1981cat 2224.422 kb on + strand, within Rv1981cat 2224.422 kb on + strand, within Rv1981cat 2224.422 kb on + strand, within Rv1981cat 2224.423 kb on - strand, within Rv1981cat 2224.458 kb on + strand, within Rv1981cat 2224.518 kb on + strand, within Rv1981cat 2224.518 kb on + strand, within Rv1981cat 2224.519 kb on - strand, within Rv1981cat 2224.578 kb on + strand, within Rv1981cat 2224.587 kb on + strand, within Rv1981cat 2224.587 kb on + strand, within Rv1981cat 2224.587 kb on + strand, within Rv1981cat 2224.588 kb on - strand, within Rv1981cat 2224.588 kb on - strand, within Rv1981cat 2224.590 kb on + strand, within Rv1981cat 2224.591 kb on - strand, within Rv1981cat 2224.591 kb on - strand, within Rv1981cat 2224.651 kb on + strand, within Rv1981cat 2224.652 kb on - strand, within Rv1981cat 2224.668 kb on + strand, within Rv1981cat 2224.668 kb on + strand, within Rv1981cat 2224.668 kb on + strand, within Rv1981cat 2224.669 kb on - strand, within Rv1981cat 2224.680 kb on + strand, within Rv1981cat 2224.681 kb on - strand, within Rv1981cat 2224.756 kb on - strand, within Rv1981cat 2224.758 kb on + strand, within Rv1981cat 2224.759 kb on - strand, within Rv1981cat 2224.792 kb on - strand, within Rv1981cat 2224.792 kb on - strand, within Rv1981cat 2224.792 kb on - strand, within Rv1981cat 2224.867 kb on - strand, within Rv1981cat 2224.867 kb on - strand, within Rv1981cat 2224.867 kb on - strand, within Rv1981cat 2224.867 kb on - strand, within Rv1981cat 2225.238 kb on - strandat 2225.238 kb on - strandat 2225.333 kb on + strandat 2225.333 kb on + strandat 2225.333 kb on + strandat 2225.334 kb on - strandat 2225.334 kb on - strandat 2225.334 kb on - strandat 2225.334 kb on - strandat 2225.334 kb on - strandat 2225.523 kb on - strand, within Rv1982cat 2225.529 kb on + strand, within Rv1982cat 2225.530 kb on - strand, within Rv1982cat 2225.530 kb on - strand, within Rv1982cat 2225.530 kb on - strand, within Rv1982cat 2225.864 kb on - strandat 2226.137 kb on + strandat 2226.160 kb on - strandat 2226.163 kb on + strandat 2226.163 kb on + strandat 2226.163 kb on + strandat 2226.164 kb on - strandat 2226.164 kb on - strandat 2226.206 kb on + strandat 2226.305 kb on + strandat 2226.305 kb on + strandat 2226.305 kb on + strandat 2226.305 kb on + strandat 2226.305 kb on + strandat 2226.305 kb on + strandat 2226.305 kb on + strandat 2226.305 kb on + strandat 2226.306 kb on - strandat 2226.306 kb on - strandat 2226.306 kb on - strandat 2226.306 kb on - strandat 2226.306 kb on - strandat 2226.427 kb on + strand, within Rv1983at 2226.428 kb on - strand, within Rv1983at 2226.502 kb on + strand, within Rv1983at 2226.503 kb on - strand, within Rv1983at 2226.503 kb on - strand, within Rv1983at 2226.667 kb on + strand, within Rv1983at 2226.689 kb on - strand, within Rv1983

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid 10 mM (N)
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2,224,413 + Rv1981c 0.20 -0.4
2,224,413 + Rv1981c 0.20 -0.1
2,224,413 + Rv1981c 0.20 -0.4
2,224,413 + Rv1981c 0.20 -0.3
2,224,414 - Rv1981c 0.20 -0.7
2,224,422 + Rv1981c 0.21 -0.5
2,224,422 + Rv1981c 0.21 +0.7
2,224,422 + Rv1981c 0.21 -0.3
2,224,423 - Rv1981c 0.21 -0.5
2,224,458 + Rv1981c 0.25 +0.0
2,224,518 + Rv1981c 0.31 +0.1
2,224,518 + Rv1981c 0.31 +0.3
2,224,519 - Rv1981c 0.31 -0.1
2,224,578 + Rv1981c 0.37 -1.5
2,224,587 + Rv1981c 0.38 +0.9
2,224,587 + Rv1981c 0.38 -0.0
2,224,587 + Rv1981c 0.38 -0.7
2,224,588 - Rv1981c 0.38 -0.5
2,224,588 - Rv1981c 0.38 +0.3
2,224,590 + Rv1981c 0.38 -0.0
2,224,591 - Rv1981c 0.38 -1.1
2,224,591 - Rv1981c 0.38 -0.4
2,224,651 + Rv1981c 0.44 -0.9
2,224,652 - Rv1981c 0.45 +1.6
2,224,668 + Rv1981c 0.46 -0.5
2,224,668 + Rv1981c 0.46 -0.2
2,224,668 + Rv1981c 0.46 +0.2
2,224,669 - Rv1981c 0.46 +0.9
2,224,680 + Rv1981c 0.47 -0.1
2,224,681 - Rv1981c 0.48 -0.1
2,224,756 - Rv1981c 0.55 +0.5
2,224,758 + Rv1981c 0.56 -0.3
2,224,759 - Rv1981c 0.56 -0.2
2,224,792 - Rv1981c 0.59 -0.3
2,224,792 - Rv1981c 0.59 -0.6
2,224,792 - Rv1981c 0.59 +0.1
2,224,867 - Rv1981c 0.67 -1.1
2,224,867 - Rv1981c 0.67 +2.0
2,224,867 - Rv1981c 0.67 -0.5
2,224,867 - Rv1981c 0.67 +0.5
2,225,238 - -0.2
2,225,238 - -0.9
2,225,333 + -0.2
2,225,333 + +0.0
2,225,333 + -0.0
2,225,334 - +0.1
2,225,334 - -1.0
2,225,334 - +0.7
2,225,334 - +1.6
2,225,334 - +0.5
2,225,523 - Rv1982c 0.26 -0.0
2,225,529 + Rv1982c 0.28 +1.9
2,225,530 - Rv1982c 0.28 +0.3
2,225,530 - Rv1982c 0.28 +0.4
2,225,530 - Rv1982c 0.28 -0.2
2,225,864 - -0.2
2,226,137 + -1.1
2,226,160 - -0.2
2,226,163 + -0.0
2,226,163 + -0.4
2,226,163 + -0.0
2,226,164 - -0.0
2,226,164 - +0.0
2,226,206 + -0.3
2,226,305 + -0.3
2,226,305 + -0.0
2,226,305 + -0.1
2,226,305 + -0.6
2,226,305 + -0.3
2,226,305 + -0.3
2,226,305 + +0.0
2,226,305 + +0.6
2,226,306 - +0.3
2,226,306 - -0.8
2,226,306 - +1.6
2,226,306 - -1.4
2,226,306 - -0.2
2,226,427 + Rv1983 0.11 -0.2
2,226,428 - Rv1983 0.11 +2.5
2,226,502 + Rv1983 0.15 -0.1
2,226,503 - Rv1983 0.15 -0.3
2,226,503 - Rv1983 0.15 +1.0
2,226,667 + Rv1983 0.25 -0.6
2,226,689 - Rv1983 0.27 -0.1

Or see this region's nucleotide sequence