Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2555c

Experiment: L-Asparagine 10 mM (N)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2553c and Rv2554c overlap by 8 nucleotidesRv2554c and Rv2555c are separated by 0 nucleotidesRv2555c and Rv2556c are separated by 90 nucleotidesRv2556c and Rv2557 are separated by 106 nucleotides Rv2553c: Rv2553c - Probable conserved membrane protein, at 2,872,012 to 2,873,265 Rv2553c Rv2554c: Rv2554c - Conserved protein, at 2,873,258 to 2,873,770 Rv2554c Rv2555c: Rv2555c - Probable alanyl-tRNA synthetase AlaS (alanine--tRNA ligase) (alanine translase) (ALARS), at 2,873,771 to 2,876,485 Rv2555c Rv2556c: Rv2556c - Conserved hypothetical protein, at 2,876,576 to 2,876,965 Rv2556c Rv2557: Rv2557 - Conserved protein, at 2,877,072 to 2,877,746 Rv2557 Position (kb) 2873 2874 2875 2876 2877Strain fitness (log2 ratio) -1 0 1 2 3 4at 2872.875 kb on - strand, within Rv2553cat 2876.512 kb on - strandat 2876.541 kb on - strandat 2876.541 kb on - strandat 2876.743 kb on - strand, within Rv2556cat 2876.837 kb on - strand, within Rv2556cat 2876.989 kb on + strandat 2876.990 kb on - strandat 2877.067 kb on - strandat 2877.147 kb on - strand, within Rv2557at 2877.147 kb on - strand, within Rv2557at 2877.204 kb on - strand, within Rv2557at 2877.242 kb on - strand, within Rv2557at 2877.332 kb on - strand, within Rv2557at 2877.478 kb on + strand, within Rv2557at 2877.478 kb on + strand, within Rv2557at 2877.479 kb on - strand, within Rv2557

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction L-Asparagine 10 mM (N)
remove
2,872,875 - Rv2553c 0.69 -1.4
2,876,512 - -1.4
2,876,541 - -0.1
2,876,541 - -0.4
2,876,743 - Rv2556c 0.43 -0.3
2,876,837 - Rv2556c 0.67 -0.2
2,876,989 + +0.8
2,876,990 - -1.0
2,877,067 - +4.2
2,877,147 - Rv2557 0.11 -0.3
2,877,147 - Rv2557 0.11 -0.3
2,877,204 - Rv2557 0.20 +0.0
2,877,242 - Rv2557 0.25 -0.8
2,877,332 - Rv2557 0.39 -0.9
2,877,478 + Rv2557 0.60 -0.1
2,877,478 + Rv2557 0.60 -0.2
2,877,479 - Rv2557 0.60 -0.3

Or see this region's nucleotide sequence