Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2048c

Experiment: L-Alanine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2047c and Rv2048c are separated by 4 nucleotidesRv2048c and Rv2049c are separated by 306 nucleotidesRv2049c and Rv2050 are separated by 303 nucleotides Rv2047c: Rv2047c - Conserved hypothetical protein, at 2,291,962 to 2,294,526 Rv2047c Rv2048c: Rv2048c - Polyketide synthase Pks12, at 2,294,531 to 2,306,986 Rv2048c Rv2049c: Rv2049c - Conserved hypothetical protein, at 2,307,293 to 2,307,517 Rv2049c Rv2050: Rv2050 - Conserved protein, at 2,307,821 to 2,308,156 Rv2050 Position (kb) 2294 2295 2296 2297 2298 2299 2300 2301 2302 2303 2304 2305 2306 2307Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2293.897 kb on + strand, within Rv2047cat 2293.914 kb on + strand, within Rv2047cat 2293.983 kb on + strand, within Rv2047cat 2294.078 kb on + strand, within Rv2047cat 2294.078 kb on + strand, within Rv2047cat 2294.724 kb on - strandat 2294.793 kb on + strandat 2298.252 kb on + strand, within Rv2048cat 2298.252 kb on + strand, within Rv2048cat 2300.355 kb on + strand, within Rv2048cat 2301.090 kb on - strand, within Rv2048cat 2302.542 kb on + strand, within Rv2048cat 2302.543 kb on - strand, within Rv2048cat 2302.981 kb on - strand, within Rv2048cat 2302.981 kb on - strand, within Rv2048cat 2303.004 kb on - strand, within Rv2048cat 2303.781 kb on + strand, within Rv2048cat 2303.782 kb on - strand, within Rv2048cat 2304.739 kb on - strand, within Rv2048cat 2304.739 kb on - strand, within Rv2048cat 2306.473 kb on - strandat 2306.709 kb on + strandat 2306.710 kb on - strandat 2306.716 kb on + strandat 2306.988 kb on - strandat 2306.990 kb on + strandat 2306.991 kb on - strandat 2306.991 kb on - strandat 2307.000 kb on + strandat 2307.001 kb on - strandat 2307.010 kb on + strandat 2307.014 kb on - strandat 2307.014 kb on - strandat 2307.117 kb on + strandat 2307.117 kb on + strandat 2307.118 kb on - strandat 2307.153 kb on - strandat 2307.254 kb on - strandat 2307.294 kb on + strandat 2307.429 kb on + strand, within Rv2049cat 2307.531 kb on + strandat 2307.561 kb on + strandat 2307.656 kb on + strandat 2307.656 kb on + strandat 2307.656 kb on + strandat 2307.657 kb on - strandat 2307.657 kb on - strandat 2307.723 kb on + strandat 2307.776 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Alanine 10 mM (N)
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2,293,897 + Rv2047c 0.75 -2.0
2,293,914 + Rv2047c 0.76 -2.7
2,293,983 + Rv2047c 0.79 -1.4
2,294,078 + Rv2047c 0.82 -2.3
2,294,078 + Rv2047c 0.82 -2.0
2,294,724 - -2.6
2,294,793 + -1.9
2,298,252 + Rv2048c 0.30 -0.4
2,298,252 + Rv2048c 0.30 -1.6
2,300,355 + Rv2048c 0.47 -1.1
2,301,090 - Rv2048c 0.53 -1.2
2,302,542 + Rv2048c 0.64 -2.1
2,302,543 - Rv2048c 0.64 -1.9
2,302,981 - Rv2048c 0.68 -1.3
2,302,981 - Rv2048c 0.68 -1.9
2,303,004 - Rv2048c 0.68 -1.1
2,303,781 + Rv2048c 0.74 -1.2
2,303,782 - Rv2048c 0.74 -1.6
2,304,739 - Rv2048c 0.82 -1.8
2,304,739 - Rv2048c 0.82 -3.0
2,306,473 - -1.2
2,306,709 + -0.6
2,306,710 - -2.5
2,306,716 + +0.1
2,306,988 - -0.1
2,306,990 + -2.0
2,306,991 - -0.1
2,306,991 - -1.8
2,307,000 + -1.3
2,307,001 - +1.7
2,307,010 + -0.3
2,307,014 - +1.1
2,307,014 - -0.0
2,307,117 + -0.8
2,307,117 + -0.3
2,307,118 - -0.1
2,307,153 - -0.1
2,307,254 - -0.5
2,307,294 + -0.4
2,307,429 + Rv2049c 0.60 -0.4
2,307,531 + -0.5
2,307,561 + -0.2
2,307,656 + +0.1
2,307,656 + -0.2
2,307,656 + +0.3
2,307,657 - +0.3
2,307,657 - +1.9
2,307,723 + -0.1
2,307,776 + -0.1

Or see this region's nucleotide sequence