Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3315c

Experiment: L-Alanine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3314c and Rv3315c overlap by 4 nucleotidesRv3315c and Rv3316 are separated by 236 nucleotidesRv3316 and Rv3317 overlap by 4 nucleotides Rv3314c: Rv3314c - Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase), at 3,702,184 to 3,703,467 Rv3314c Rv3315c: Rv3315c - Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase), at 3,703,464 to 3,703,865 Rv3315c Rv3316: Rv3316 - Probable succinate dehydrogenase (cytochrome B-556 subunit) SdhC (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase), at 3,704,102 to 3,704,440 Rv3316 Rv3317: Rv3317 - Probable succinate dehydrogenase (hydrophobic membrane anchor subunit) SdhD (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase), at 3,704,437 to 3,704,871 Rv3317 Position (kb) 3703 3704Strain fitness (log2 ratio) -1 0 1 2at 3702.903 kb on + strand, within Rv3314cat 3703.225 kb on + strand, within Rv3314cat 3703.368 kb on + strandat 3703.370 kb on + strandat 3703.370 kb on + strandat 3703.371 kb on - strandat 3703.371 kb on - strandat 3703.714 kb on + strand, within Rv3315cat 3703.714 kb on + strand, within Rv3315cat 3703.805 kb on - strand, within Rv3315cat 3703.805 kb on - strand, within Rv3315cat 3703.805 kb on - strand, within Rv3315cat 3703.844 kb on + strandat 3703.910 kb on + strandat 3704.013 kb on + strandat 3704.084 kb on + strandat 3704.101 kb on + strandat 3704.102 kb on - strandat 3704.116 kb on - strandat 3704.205 kb on - strand, within Rv3316at 3704.263 kb on - strand, within Rv3316at 3704.339 kb on + strand, within Rv3316at 3704.755 kb on + strand, within Rv3317at 3704.836 kb on + strandat 3704.836 kb on + strandat 3704.836 kb on + strandat 3704.844 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Alanine 10 mM (N)
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3,702,903 + Rv3314c 0.56 -0.5
3,703,225 + Rv3314c 0.81 +0.3
3,703,368 + -0.5
3,703,370 + -0.2
3,703,370 + -0.1
3,703,371 - +1.2
3,703,371 - -0.0
3,703,714 + Rv3315c 0.62 -1.1
3,703,714 + Rv3315c 0.62 -0.3
3,703,805 - Rv3315c 0.85 -0.7
3,703,805 - Rv3315c 0.85 -0.2
3,703,805 - Rv3315c 0.85 -0.4
3,703,844 + +0.8
3,703,910 + -0.3
3,704,013 + -0.6
3,704,084 + -1.6
3,704,101 + +0.3
3,704,102 - +0.3
3,704,116 - -0.8
3,704,205 - Rv3316 0.30 +0.1
3,704,263 - Rv3316 0.47 +0.5
3,704,339 + Rv3316 0.70 +0.2
3,704,755 + Rv3317 0.73 +1.8
3,704,836 + -0.6
3,704,836 + +0.2
3,704,836 + +0.2
3,704,844 - -0.0

Or see this region's nucleotide sequence