Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2530A

Experiment: L-Alanine 10 mM (N)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2529 and Rv2530c are separated by 0 nucleotidesRv2530c and Rv2530A overlap by 4 nucleotidesRv2530A and Rv2531c are separated by 30 nucleotides Rv2529: Rv2529 - Hypothetical protein, at 2,852,875 to 2,854,266 Rv2529 Rv2530c: Rv2530c - Possible toxin VapC39. Contains PIN domain., at 2,854,267 to 2,854,686 Rv2530c Rv2530A: Rv2530A - Possible antitoxin VapB39, at 2,854,683 to 2,854,907 Rv2530A Rv2531c: Rv2531c - Probable amino acid decarboxylase, at 2,854,938 to 2,857,781 Rv2531c Position (kb) 2854 2855Strain fitness (log2 ratio) -1 0 1 2 3at 2853.935 kb on - strand, within Rv2529at 2854.908 kb on - strandat 2855.040 kb on + strandat 2855.122 kb on + strandat 2855.122 kb on + strandat 2855.122 kb on + strandat 2855.122 kb on + strandat 2855.162 kb on - strandat 2855.162 kb on - strandat 2855.241 kb on + strand, within Rv2531cat 2855.314 kb on + strand, within Rv2531cat 2855.323 kb on + strand, within Rv2531cat 2855.400 kb on + strand, within Rv2531cat 2855.445 kb on + strand, within Rv2531cat 2855.524 kb on + strand, within Rv2531cat 2855.525 kb on - strand, within Rv2531cat 2855.580 kb on - strand, within Rv2531cat 2855.755 kb on + strand, within Rv2531cat 2855.756 kb on - strand, within Rv2531cat 2855.878 kb on + strand, within Rv2531cat 2855.878 kb on + strand, within Rv2531cat 2855.878 kb on + strand, within Rv2531cat 2855.879 kb on - strand, within Rv2531cat 2855.879 kb on - strand, within Rv2531c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Alanine 10 mM (N)
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2,853,935 - Rv2529 0.76 -0.1
2,854,908 - -0.1
2,855,040 + +0.4
2,855,122 + -0.4
2,855,122 + +0.1
2,855,122 + -0.2
2,855,122 + -0.5
2,855,162 - -0.3
2,855,162 - -0.2
2,855,241 + Rv2531c 0.11 -0.1
2,855,314 + Rv2531c 0.13 -0.7
2,855,323 + Rv2531c 0.14 +2.8
2,855,400 + Rv2531c 0.16 +0.3
2,855,445 + Rv2531c 0.18 +0.6
2,855,524 + Rv2531c 0.21 -0.7
2,855,525 - Rv2531c 0.21 +0.0
2,855,580 - Rv2531c 0.23 -0.4
2,855,755 + Rv2531c 0.29 +2.3
2,855,756 - Rv2531c 0.29 +0.0
2,855,878 + Rv2531c 0.33 +0.8
2,855,878 + Rv2531c 0.33 -0.1
2,855,878 + Rv2531c 0.33 +0.5
2,855,879 - Rv2531c 0.33 -0.3
2,855,879 - Rv2531c 0.33 -0.1

Or see this region's nucleotide sequence