Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0201c

Experiment: Palmitic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0199 and Rv0200 overlap by 4 nucleotidesRv0200 and Rv0201c overlap by 4 nucleotidesRv0201c and Rv0202c overlap by 4 nucleotides Rv0199: Rv0199 - Probable conserved membrane protein, at 236,550 to 237,209 Rv0199 Rv0200: Rv0200 - Possible conserved transmembrane protein, at 237,206 to 237,895 Rv0200 Rv0201c: Rv0201c - Conserved protein, at 237,892 to 238,395 Rv0201c Rv0202c: Rv0202c - Probable conserved transmembrane transport protein MmpL11, at 238,392 to 241,292 Rv0202c Position (kb) 237 238 239Strain fitness (log2 ratio) -1 0 1at 236.988 kb on - strand, within Rv0199at 237.659 kb on + strand, within Rv0200at 237.659 kb on + strand, within Rv0200at 237.659 kb on + strand, within Rv0200at 238.123 kb on - strand, within Rv0201cat 238.243 kb on + strand, within Rv0201cat 238.300 kb on - strand, within Rv0201cat 238.573 kb on + strandat 238.623 kb on - strandat 238.961 kb on + strand, within Rv0202cat 238.961 kb on + strand, within Rv0202cat 239.302 kb on - strand, within Rv0202cat 239.392 kb on + strand, within Rv0202c

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Per-strain Table

Position Strand Gene LocusTag Fraction Palmitic 100 uM (C)
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236,988 - Rv0199 0.66 +0.4
237,659 + Rv0200 0.66 -0.3
237,659 + Rv0200 0.66 +1.0
237,659 + Rv0200 0.66 -0.2
238,123 - Rv0201c 0.46 +0.7
238,243 + Rv0201c 0.70 +0.4
238,300 - Rv0201c 0.81 +0.5
238,573 + -0.7
238,623 - -0.6
238,961 + Rv0202c 0.20 -1.7
238,961 + Rv0202c 0.20 -1.6
239,302 - Rv0202c 0.31 -0.4
239,392 + Rv0202c 0.34 -0.6

Or see this region's nucleotide sequence